全文获取类型
收费全文 | 58916篇 |
免费 | 5501篇 |
国内免费 | 4404篇 |
专业分类
耳鼻咽喉 | 445篇 |
儿科学 | 738篇 |
妇产科学 | 616篇 |
基础医学 | 6559篇 |
口腔科学 | 1103篇 |
临床医学 | 7784篇 |
内科学 | 8614篇 |
皮肤病学 | 487篇 |
神经病学 | 2592篇 |
特种医学 | 1996篇 |
外国民族医学 | 32篇 |
外科学 | 6462篇 |
综合类 | 10323篇 |
现状与发展 | 10篇 |
一般理论 | 3篇 |
预防医学 | 4195篇 |
眼科学 | 1652篇 |
药学 | 6600篇 |
47篇 | |
中国医学 | 3456篇 |
肿瘤学 | 5107篇 |
出版年
2024年 | 266篇 |
2023年 | 1000篇 |
2022年 | 2513篇 |
2021年 | 3062篇 |
2020年 | 2388篇 |
2019年 | 1987篇 |
2018年 | 2078篇 |
2017年 | 1938篇 |
2016年 | 1859篇 |
2015年 | 2768篇 |
2014年 | 3446篇 |
2013年 | 3135篇 |
2012年 | 4395篇 |
2011年 | 4765篇 |
2010年 | 3197篇 |
2009年 | 2564篇 |
2008年 | 3224篇 |
2007年 | 3165篇 |
2006年 | 3009篇 |
2005年 | 2693篇 |
2004年 | 1908篇 |
2003年 | 1845篇 |
2002年 | 1496篇 |
2001年 | 1237篇 |
2000年 | 1279篇 |
1999年 | 1373篇 |
1998年 | 874篇 |
1997年 | 861篇 |
1996年 | 670篇 |
1995年 | 627篇 |
1994年 | 601篇 |
1993年 | 338篇 |
1992年 | 421篇 |
1991年 | 335篇 |
1990年 | 270篇 |
1989年 | 257篇 |
1988年 | 240篇 |
1987年 | 214篇 |
1986年 | 169篇 |
1985年 | 148篇 |
1984年 | 56篇 |
1983年 | 42篇 |
1982年 | 25篇 |
1981年 | 27篇 |
1980年 | 13篇 |
1979年 | 30篇 |
1978年 | 2篇 |
1962年 | 1篇 |
1961年 | 1篇 |
1929年 | 1篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
31.
采用 TAD 方案治疗急性非淋巴细胞性白血病(ANLL)12例,年龄17~47岁。总有效率为66.7%,完全缓解率(CR)为41.7%。5例获 CR 的时间是26~66天,平均53天,较国内其它方案为快。CR 时间为2~9月,平均6.2月,较其它方案又较短。TAD 方案对心脏的毒性作用轻微。TAD 方案对5例获 CR 者,于诱导治疗第一疗程后,除1例外,骨髓中白血病细胞百分比下降均不明显;但于第二疗程后,白血病细胞全部减少到骨髓有核细胞总数的20%/以下,这种现象似可作为本方案预后的观察指标。 相似文献
32.
33.
对1例巨大甲状腺肿瘤患者在体外膜肺氧合辅助下行肿瘤切除术,手术顺利,历时12.0h,切除肿瘤500g,住院23d患者康复出院。提出术前充分评估患者状况、做好心理护理和器械物品准备,术中熟悉体外膜肺氧合的操作方法、积极配合手术、密切观察病情等,是获得良好手术效果的重要环节。 相似文献
34.
目的探讨术中实时超声导航在脑动静脉畸形(AVM)外科治疗中的应用价值。方法26例脑AVM显微手术切除术中,使用Aloka SSD 4000型超声检查仪扫描,进行AVM定位、辨别供血动脉和引流静脉;确定血肿与AVM的关系以及血流动力学监测。病变切除后重复超声检查AVM残留与否,并与术后脑血管造影结果对比。结果26例畸形血管团均住实时超声下清晰显示并获得全切除。血肿区为高同声无血流信号;供血动脉与正常血管在血流动力学上有差别;术中超声影像所示的病变全切除为术后血管造影所证实。结论术中实时超声能够对脑AVM进行准确定位,指导皮质切口的设计,并可判定病灶是否全切除.对于术前的MRI、DSA检查起到很有价值的补充作用。 相似文献
35.
M A Ye?ilipek G Lüleci N Oygür S Berker O Yegin 《The Turkish journal of pediatrics》1992,34(4):251-254
Cytogenetic abnormalities are rarely found in patients with juvenile chronic myelogenous leukemia (JCML). In patients with chromosomal abnormalities, chromosomes 7 and 8 are usually involved. A case of JCML with 47 XXX and a 46 XX karyotype is described and the literature is reviewed. To our knowledge, this is the first case ever to have been reported. 相似文献
36.
叶玲娣 《中国心血管病研究杂志》2004,2(2):122-123
目的为了解旁道位置与室上性心动过速初次发作时年龄及性别的关系.方法对128例已进行过射频消融的患者进行了回顾性分析.结果男性左侧旁道发病时平均年龄大于右侧及中隔旁道平均为14岁和9岁;大于女性左侧旁道7岁,男性显性旁道发病时平均年龄小于隐匿性旁道7岁.而女性显性旁道与隐匿性旁道、左侧旁道与右侧旁道发病时平均年龄无显著性差异.结论旁道位置与室上速初次发作时年龄及性别有关. 相似文献
37.
38.
39.
The effect associated with the substitution of adenine (A) for guanidine (G) in the promoter region of the apolipoprotein AI gene (?75 bp) with plasma apo AI and high-density lipoprotein (HDL) levels was investigated in the European Atherosclerosis Research Study (EARS). This is a study of healthy offspring (cases) of fathers who had suffered premature myocardial infarction (MI) before age 55 years (n = 565) and age- and sex-matched controls (n = 1,078) from 12 European countries, divided into 5 regions based on geography and language. The frequency of the polymorphism was not significantly different among the regions and the relative frequency of the rare A allele was similar in cases and controls (0.159 vs. 0.142) combining data from all regions. Individuals with one or more A allele had significantly higher plasma apo AI levels (P < 0.05) than individuals homozygous for the G allele. This effect was consistent in all regions. The data were analyzed separately in males and females. In females, those with one or more A allele had significantly higher apo AI levels (P = 0.05) than individuals homozygous for the G allele, and this raising effect of the A allele was greater in cases than controls for both apo AI (5.23% vs. 1.56%) and HDL (4.48% vs. 1.89%). In males, the A allele was associated with higher levels of apo AI and HDL, but the effect was much smaller and the differences did not reach statistical significance. In the females, where the effect of the A allele was strongest, the effect on apo AI associated with genotype was evident in non-smokers, and individuals with one or two A alleles had 3.6% higher apo AI and 3.14% higher HDL levels than individuals homozygous for the G allele. However, in the female smokers the raising effect of the A allele was greatly reduced (0.56%). Thus genetic variation in the promoter region of the apo AI gene is associated with differences in apo AI and HDL levels in healthy individuals throughout Europe, but the effect is modulated by gender, environmental factors such as smoking, and a family history of MI. 相似文献
40.
Role of endothelin in the pathogenesis of hypertension in spontaneously hypertensive and 2 kidneys 1 clip rats. 总被引:1,自引:0,他引:1
The plasma endothelin (ET) level in spontaneously hypertensive rats (SHR) and 2K1C hypertension animal models and its vasoconstrictive effect on renal and tail arteries were studied. The results demonstrated that there was no difference in plasma ET level between the hypertensive groups SHR, 2K1C, normotensive control groups Wistar Kyot (WKY) and Sprague Dawley (SD), while the vasoconstrictive effect of ET in SHR was more dominant than in WKY. The EC50 of the renal and tail arteries in SHR (0.8912 +/- 0.1662 x 10(-8) M, 0.6103 +/- 0.0878 x 10(-8) M) was apparently lower than that in WKY (1.77 +/- 0.2991 x 10(-8) M, 1.2267 +/- 0.2502 x 10(-8) M, P less than 0.05), but no difference was found in 2K1C and SD rats. The four groups of animals exhibited no difference of such effects as response to norepine-phrine (NA). The findings suggested that the increased arteriole sensitivity to ET be an important factor in the pathogenesis of hypertension in SHR.
相似文献