全文获取类型
收费全文 | 383567篇 |
免费 | 21036篇 |
国内免费 | 13902篇 |
专业分类
耳鼻咽喉 | 2996篇 |
儿科学 | 8893篇 |
妇产科学 | 5730篇 |
基础医学 | 40950篇 |
口腔科学 | 5431篇 |
临床医学 | 40045篇 |
内科学 | 61136篇 |
皮肤病学 | 3135篇 |
神经病学 | 26657篇 |
特种医学 | 16239篇 |
外国民族医学 | 107篇 |
外科学 | 50040篇 |
综合类 | 37140篇 |
现状与发展 | 43篇 |
一般理论 | 24篇 |
预防医学 | 32236篇 |
眼科学 | 8332篇 |
药学 | 32257篇 |
213篇 | |
中国医学 | 13375篇 |
肿瘤学 | 33526篇 |
出版年
2024年 | 857篇 |
2023年 | 3478篇 |
2022年 | 9042篇 |
2021年 | 11374篇 |
2020年 | 8599篇 |
2019年 | 7306篇 |
2018年 | 28873篇 |
2017年 | 23972篇 |
2016年 | 25618篇 |
2015年 | 11004篇 |
2014年 | 13178篇 |
2013年 | 12221篇 |
2012年 | 23397篇 |
2011年 | 38433篇 |
2010年 | 29986篇 |
2009年 | 20260篇 |
2008年 | 30939篇 |
2007年 | 32488篇 |
2006年 | 11183篇 |
2005年 | 12235篇 |
2004年 | 9937篇 |
2003年 | 10231篇 |
2002年 | 7429篇 |
2001年 | 4477篇 |
2000年 | 4797篇 |
1999年 | 4585篇 |
1998年 | 2871篇 |
1997年 | 2901篇 |
1996年 | 2185篇 |
1995年 | 2138篇 |
1994年 | 1883篇 |
1993年 | 1124篇 |
1992年 | 1509篇 |
1991年 | 1346篇 |
1990年 | 1134篇 |
1989年 | 1012篇 |
1988年 | 923篇 |
1987年 | 763篇 |
1986年 | 564篇 |
1985年 | 488篇 |
1984年 | 235篇 |
1983年 | 207篇 |
1982年 | 129篇 |
1981年 | 139篇 |
1980年 | 125篇 |
1979年 | 121篇 |
1978年 | 62篇 |
1974年 | 63篇 |
1938年 | 60篇 |
1932年 | 57篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
Peter Angelos 《World journal of surgery》2009,33(4):609-611
72.
背景: 前期研究表明广西18~22岁少数民族学生体质量偏轻。
目的:拟进一步了解广西2645名少数民族学生体型及体质健康状况,寻找影响的关联因子。
设计、时间及地点:追踪调查,于2004-12/2007-12在广西民族大学完成。
对象:广西民族大学2003/2005三次体质健康测试的全体学生2 645人。男1 337人,女1308人,年龄为18~20岁,共15个民族。
方法:根据2003年教育部、体育总局《学生体质健康标准(试行方案)》和实施方法分为形态指标、技能指标和身体素质指标3大类。对2 645名少数民族身体机能与体质量指数变化的跟踪调查。
主要观察指标:身高、体质量、肺活量、立定跳远、坐位体前屈、体质量指数。
结果:①广西民族大学2003级学生大学3年期间男生身高、体质量增长率比全国同期多2.45%,身体形态发育正处于高峰期,女生成偏瘦型体型,身体形态发育情况总体欠佳。②男女学生在刚入校时肺活量机能较差,远远低于同期全国平均水平。3年后男生肺活量增长率为11.55%、女生肺活量增长率为27.72%,分别高于全国同期肺活量增长率。③坐位体前屈机能高于同期全国平均水平,男生呈逐年上升趋势,同期全国男性呈下降趋势;同期全国乡村女生均呈逐年上升趋势。④立定跳远机能提高较大,3年后增长率为18.15%,明显高于全国同期立定跳远增长率水平的2.61%。女生立定跳远机能总体不如全国同期水平。⑤体质量指数总体与同期全国乡村男女学生体质量指数比较稍低一些(P < 0.01)。
结论:2 645名少数民族学生发育正处于高峰期;肺活量机能不及全国同期平均水平。男女体质量指数分布有所不同,体质量偏轻者女生多于男生,表明学生营养状况总体欠佳。 相似文献
73.
Kentaroh Miyoshi Minoru Naito Tsuyoshi Ueno Shinji Hato Hideo Ino 《General thoracic and cardiovascular surgery》2009,57(11):629-632
A benign esophageal leiomyoma with abnormally increased fluorine-18-fluorodeoxyglucose uptake on positron emission tomography
(PET) was resected thoracoscopically. The tumor, of which the maximum standardized uptake value of the lesion was 4.7, was
well defined and 38 mm in diameter. Neither mitotic activity nor degeneration was found histologically; and immunoreactivity
for CD34, CD117, MIB-1, and glucose transporter-1 was negative immunohistochemically. A diagnosis of gastrointestinal stromal
tumor was ruled out by an oncogenic kinase gene mutation study. This case cautions against PET-dependent evaluation for malignant
potential of esophageal submucosal tumors. 相似文献
74.
75.
Statutory reimbursement agencies as well as private insurers throughout member states of the Organization for Economic Cooperation and Development (OECD) reimburse the cost of medicines on the basis of criteria that include robust clinical evidence, budget impact analysis, and incremental cost effectiveness. The Centers for Medicare and Medicaid Services (CMS) in the US are no exception to this rule and are, in principle, seeking to maximize benefit for their Medicare enrollees, whilst ensuring reasonable drug outlays for the small number of drugs that they reimburse. This paper provides a retrospective analysis of the way two functionally equivalent drugs are treated for reimbursement purposes by the CMS; the period under consideration was 2001–3. The two drugs, epoetin-α and darbepoetin-α, are used for the treatment of anemia in renal failure and in patients receiving chemotherapy. By reviewing the publicly available pharmacological and clinical data of epoetin-α and darbepoetin-α, the paper confirms the two drugs’ functional equivalence, despite their structural differences. The implications of dose conversion ratios and costs to Medicare are subsequently explored. It is argued that the issue of dose equivalence between epoetin-α and darbepoetin-α has significant implications for patients, practitioners, and payors. A payor’s perspective is adopted in this respect, whereby clinical evidence and pricing data are used simultaneously. Based on the clinical evidence, a dose conversion ratio for epoetin-α:darbepoetin-α is established, which achieves a comparable clinical effect for the two drugs and this is set to be <254IU:1μg. The incremental costs to Medicare are calculated subsequently. The Average Wholesale Price and the Outpatient Prospective Payment System rule that Medicare uses to reimburse providers are used and suggest that treatment of cancer patients with chemotherapy-related anemia with epoetin-α would save Medicare an estimated $US600 million each year. Patients would also benefit significantly in terms of lower co-payments for epoetin-α. The evidence is supportive of the decision made by the CMS to reimburse the two drugs at the rate reflecting the achievement of comparable clinical effects and therefore reducing the pass-through payments for darbepoetin-α to zero for the 2002–3 fiscal year. 相似文献
76.
本文对14例体外循环下心内直视手术病人采用放免法,于不同时段测定体外循环转流期间血浆的环核苷酸cAMP 和cGMP 变化。结果表明,在体外循环期间,cAMP和cGMP 浓度进行性上升,转流结束时达到最高峰,随着自身循环的恢复,cAMP 和cGNP浓度逐渐下降,术后次日恢复到术前水平;而cAMP/cGMP 比值在体外循环期间无明显变化。文中讨论了cAMP 和cGMP 变化的机制和临床意义。 相似文献
77.
Wan-Ling Ho Tien-Wu Yang Wei-Chu Chi Hong-Jen Chang Li-Min Huang Mei-Hwei Chang 《台湾医志》2005,104(6):398-401
BACKGROUND AND PURPOSE: This study investigated the characteristics of intussusception in Taiwanese children of different age groups, including the incidence, length of hospitalization and hospital costs. METHODS: Children with a diagnosis of intussusception who were hospitalized from 1999 through 2001 were identified from a nationwide health insurance claims database. The incidence of intussusception was calculated by age, gender, and season. Length of hospitalization and hospital costs were also analyzed. RESULTS: A total of 6988 cases of intussusception were identified in Taiwan from 1999 to 2001. Among them, 4859 cases occurred in children below 15 years of age. The average incidence among children below age 15 years was 34.5 per 100,000, with a peak incidence of 118.8 per 100,000 observed among children younger than 24 months old. The highest incidence of intussusception in Taiwanese children occurred between 12 and 24 months of age. According to the data for patients below 15 years of age hospitalized for intussusception in year 2000, males were more likely to be affected than females (61.3% vs 38.7%). Intussusception-related hospitalizations were rare in infants in the first few months of life, increased in those 6 to 12 months old, and peaked among children 1 to 3 years old. Among the 952 patients with intussusception admitted to hospitals in 2000, 297 (31.2%) received surgery, incurring higher median medical costs (New Taiwan Dollars [NT dollars] 42,265 or US dollars 1234) and longer median hospital stay (6.2 days) than the 655 patients who did not require surgery (NT dollars 6290 or US dollars 185 for hospitalization of 2.4 days). CONCLUSIONS: The study found that the incidence of intussusception peaked in the second year of life in Taiwanese children. There was also a male predominance and lack of seasonal variation in incidence. 相似文献
78.
Tumor metastasis to the pancreas is a rare but recognized cause of acute pancreatitis. Autopsy series have reported a 24-40% of pancreatic involvement in small cell lung cancer. However, only a very few cases of tumor-induced acute pancreatitis have been described. Budd-Chiari syndrome complicating lung cancer is a rarely reported condition. We report a 68-year-old woman with extensive small cell lung cancer with the unusual initial presentation of both acute pancreatitis and acute Budd-Chiari syndrome. This patient suffered from progressive epigastralgia for 3 weeks. Severe epigastralgia with radiation to back and progressive jaundice developed 2 days prior to admission. After admission, the liver enlarged rapidly and the ascites increased markedly. Chest roentgenogram showed a mass lesion over the left lower lung field. Poorly differentiated carcinoma cells were found in ascites and bone marrow. The patient died on the ninth day of hospitalization before chemotherapy was initiated. Prompt diagnosis of extensive-stage small cell lung cancer may allow early chemotherapy treatment which favorably influences recovery when the pancreatitis is mild. Although prolonged survival might have been expected had this patient recovered from pancreatitis and received chemotherapy, diagnosis was delayed due to difficulty in immunohistochemical diagnosis of the tumor and the unusual clinical presentation. The use of stains employing antibodies against neurofilament and neuron-specific enolase cell antigens is important for early diagnosis of poorly differentiated metastatic tumor cells. 相似文献
79.
BACKGROUND AND PURPOSE: This report describes the results of matched-unrelated-donor transplant for leukemia or myelodysplasia in the first 23 recipient children at a single medical center in Taiwan. METHODS: Between August 1994 and February 2003, 23 consecutive children with leukemia or myelodysplasia underwent matched-unrelated-donor bone marrow transplantation (BMT). The preparative regimen consisted of fractionated total body irradiation and cyclophosphamide in 6 patients; busulfan in combination with etoposide and cyclophosphamide in 4 patients who received cranial irradiation before transplantation; and busulfan and cyclophosphamide in 13 patients. RESULTS: Engraftment was achieved in 91.3% of cases. Acute graft-versus-host disease (GVHD) occurred in 18 of 21 patients who engrafted (85.7%). Event-free survival for all patients was 24.46 +/- 9.24%. The 12 children with standard-risk disease had better event-free survival than the 11 children with high-risk disease (46.88 +/- 15.03% vs 0%, p < or = 0.001). CONCLUSIONS: The major obstacles to successful matched-unrelated-donor BMT are acute GVHD, relapse and infection. Early transplantation and patient selection, prophylactic and therapeutic maneuvers for GVHD, as well as appropriate donor selection and virus prophylaxis may improve the results. 相似文献
80.