家兔急性缺氧后左心室舒张功能和心肌细胞内钙转运及能量代谢的研究

为探讨急性缺氧对家兔左心室舒张功能、心肌细胞内钙转运和能量代谢的影响。将２３只家兔分为对照组（６只）、吸入５％低氧混合气的缺氧１组（Ｈ１）（１２只）、吸入１０％低氧混合气的缺氧２组（Ｈ２）（５只），用心导管法测定左心室压力下降最大速率（ＬＶｄｐ／ｄｔｍａｘ）和压力下降时间常数（Ｔ值）；测定心肌肌浆网（ＳＲ）钙ＡＴＰ酶活性、心肌ＳＲ摄钙量、心肌组织ＡＴＰ和磷酸肌酸（ＣｒＰ）。结果，缺氧后ＬＶｄｐ／ｄｔｍａｘ下降，Ｔ值延长；缺氧组心肌ＳＲ钙ＡＴＰ酶活性及摄钙量下降；心肌线粒体钙含量升高；心肌组织ＡＴＰ和ＣｒＰ下降，心肌组织ＡＴＰ与线粒体钙含量呈负相关。提示，急性缺氧可引起左心室舒张功能障碍并影响心肌ＳＲ钙转运和心肌能量代谢。     

A morphological study of the human epipharyngeal mucosa

The epipharynx lies between the nasal cavity and oropharynx. The mucosa of the epithelium in the human epipharynx is composed of ciliated epithelium as part of the respiratory tract, squamous epithelium as representative of the digestive system and transitional epithelium. Previous studies by Ali have shown that transitional epithelium is present in a boundary line between the epipharynx and oropharynx, with numerous islets of the epithelium also located in the lateral and dorsal walls accompanied with a patchy distribution of the ciliated and squamous epithelium. Mechanical irritation caused by the anatomical properties of the epipharynx is thought to be responsible for the morphological findings present. We studied the distribution of the three different types of epithelia in the epipharynx in ten autopsy cases. Our data revealed that they showed mosaic or an “island-like” distribution on the epipharyngeal wall and their patterns of distribution were variable in each individual.     

双重法固定肩锁关节脱位

为介绍一种新方法修复肩锁关节脱位。肩锁关节脱位整复后采用双重法（交叉克氏针及8字钢丝）固定肩锁关节。结果：16例肩锁关节脱位后无一复发,关节功能无影响。结论：该法操作简单,固定牢靠,可早期行关节功能锻炼,可有效防止脱位复发。     

慢性化脓性中耳炎并发弥漫性浆液性迷路炎(附4例报告)

报告因骨疡型及胆脂瘤型中耳炎而行乳突根治术的１１１２例中并发弥漫性浆液性迷路炎４例，发生率为０．３６％，听力损失严重，经抗炎治疗，尽快施行乳突根治术，配合应用扩张血管，皮质激素，神经营养药物等治疗，获得良好效果，认为本病一经确诊后应尽快施行手术，这样不仅能解除骨疡型及胆脂瘤型中耳炎的危险性，而且还尽可能地挽救患耳的听力，尤其对两侧耳重度听力损失者意义更大。     

大鼠脑神经干细胞神经巢蛋白表达的流式细胞术检测

检测胎鼠及成年大鼠脑内神经干细胞特异性抗原神经巢蛋白的表达,判明啮齿类哺乳动物脑内神经干细胞存在的可能性及相应的部位。方法：显微手术下采取胎鼠及成年大鼠大脑与皮质下脑组织,间接荧光法标记ｎｅｓｔｉｎ,以流式细胞术检测。结果胎鼠脑内普遍存在ｎｅｓｔｉｎ阳性细胞,成年大鼠脑室旁组织中也存在ｎｅｓｔｉｎ阳性细胞。     

嗓音频谱分析中／a／,／i／音采样的比较

应用486微型计算机和北京邮电大学通用信号谱分析系统分别对30例青年女性喉病患者和36例健康对照组的/a/、/i/音嗓音信号进行频谱分析,比较其相对信噪比,结论是在频谱分析中用/a/音采样较/i/音更易检出病态嗓音.     

A longitudinal,functional study of peripheral nerve recovery in the mouse

Objectives: To verify the validity of the recently described sciatic functional index for mice to monitor neuronal functional recovery over time using a blinded, randomized, and controlled evaluation. Study Design: Surgery was performed on the left sciatic nerves of 62 C57/BL mice after randomly assigning them to one of four surgical groups: sham surgery, sciatic nerve crush, nerve transection without repair, and nerve transection followed by epineurial suture repair. Sciatic functional indices were measured before surgery and then after surgery at 10-day intervals for 90 days, using a previously described formula. Results: Sham surgery did not affect nerve function when compared with preoperative values (P > .24). Crush surgery produced a reversible nerve injury that fully recovered after 20 days. Nerve transection without repair resulted in complete functional disability without recovery of function during the 90-day follow-up interval. When transected nerves were repaired, complete functional disability was noted at day 10, with subsequent functional recovery to 26% of function at day 30. This level of recovery persisted until the 60th postoperative day when muscle contractures resulted in progressive worsening of the index. There were statistically significant differences between the sciatic functional indices of each of the groups (P < .05). Conclusions: The previously described sciatic functional index for mice is an accurate indicator of the level of sciatic neuronal function during recovery. This index represents a method of evaluating neuronal function that may provide a better reflection of the recovery parameters that are important in clinical situations. The sciatic functional index will allow for study of sciatic nerve functional recovery in genetically engineered transgenic mice.     

The effect of Rhodiola capsules on oxygen consumption of myocardium and coronary artery blood flow in dogs]

It has been proved that Rhodiola Capsules can obviously decrease the oxygen consumption of myocardium and oxygen consumption index in anesthetic dogs, decrease the coronary artery resistance, but have no marked effect on the coronary artery blood flow. The Capsules also have the function of decreasing blood presure and slowing heart rate.     

钢基Cu-5%Al激光熔覆层颗粒组织分布的定量分析

熔覆层中的颗粒相分布不仅影响材料性能，同时也是研究熔覆过程各种反应机制的主要依据。本文利用图像分析技术，定量分析了Ｑ２３５钢表面Ｃｕ５％Ａｌ激光熔覆层的富铁相颗粒分布情况。发现熔覆过程中在熔池中存在熔体对流环，熔池中的对流带动颗粒运动，是决定熔覆层颗粒分布的主要因素。     

养血清脑颗粒治疗老年期痴呆的临床疗效观察

目的：观察养血清脑颗粒对老年期痴呆的疗效。方法：治疗组老年期痴呆患者36例均应用养血清脑颗粒。详录治疗前后实验室检查数据。健康老年人34例为对照组，以其体检时所得相关指标与治疗组比较分析。结果：有效率85％，S-TC明显下降，P-SOD明显升高，P-LPO，Ht，Va降低、EET缩短。结论：养血清脑颗粒具有降脂、抗自由基损伤。改善异常血液流变，增加脑血流量等功用。对老年期痴呆防治有较好效果。