音乐疗法在肺癌术后患者化疗过程中的应用

目的探讨音乐疗法对肺癌术后化疗患者的效果。方法于2015年4月—2016年4月选择就诊于上海交通大学附属胸科医院的400例肺癌术后化疗患者,按病区分为观察组和对照组各200例,对照组予以常规护理,观察组给予化疗前晚、化疗当日、化疗当晚三个时段的音乐聆听,对比两组患者化疗后心理、恶心呕吐反应、活动度及血氧饱和度的情况。结果观察组患者焦虑自评量表(Self-Rating Anxiety Scale,SAS)得分、恶心呕吐分级、活动度KPS得分、血氧饱和度较对照组有不同程度的改善,差异有统计学意义(P0.05)。结论音乐疗法应用于肺癌术后化疗患者能指导其主动参与化疗疗程,进行住院与居家自我调适,有的放矢地降低焦虑情绪、维持生命体征、缓解胃肠不适反应,促进患者自身机体康复,更积极地接受后续治疗并重返社会。     

Utilization of phosphate rock as a sole source of phosphorus for uranium biomineralization mediated by Penicillium funiculosum

In this work, uranium(vi) biomineralization by soluble ortho-phosphate from decomposition of the phosphate rock powder, a cheap and readily available material, was studied in detail. Penicillium funiculosum was effective in solubilizing P from the phosphate rock powder, and the highest concentration of the dissolved phosphate reached 220 mg L⁻¹ (pH = 6). A yellow precipitate was immediately formed when solutions with different concentrations of uranium were treated with PO₄³⁻-containing fermentation broth, and the precipitate was identified as chernikovite by Fourier transform infrared spectroscopy, scanning electron microscope, and X-ray powder diffraction. Our study showed that the concentrations of uranium in solutions can be decreased to the level lower than maximum contaminant limit for water (50 μg L⁻¹) by the Environmental Protection Agency of China when Penicillium funiculosum was incubated for 22 days in the broth containing 5 g L⁻¹ phosphate rock powder.

In this work, uranium(vi) biomineralization by soluble ortho-phosphate from decomposition of the phosphate rock powder, a cheap and readily available material, was studied in detail.     

Structure detection of semiparametric structural equation models with Bayesian adaptive group lasso

Structural equation models (SEMs) are widely recognized as the most important statistical tool for assessing the interrelationships among latent variables. This study develops a Bayesian adaptive group least absolute shrinkage and selection operator procedure to perform simultaneous model selection and estimation for semiparametric SEMs, wherein the structural equation is formulated using the additive nonparametric functions of observed and latent variables. We propose the use of basis expansions to approximate the unknown functions. By introducing adaptive penalties to the groups of basis expansions, the nonlinear, linear, or non‐existent effects of observed and latent variables in the structural equation can be automatically detected. A simulation study demonstrates that the proposed method performs satisfactorily. This paper presents an application of revealing the observed and latent risk factors of diabetic kidney disease. Copyright © 2015 John Wiley & Sons, Ltd.     

PDCA护理管理模式在种植牙围手术期中的应用效果评价

目的 研究PDCA护理管理模式在种植牙围手术期中的临床护理效果。方法 2016年1月至2016年12月南京医科大学附属口腔医院共完成292例种植牙手术,其中2016年1月至6月围手术期实施的是常规护理,共112例,设为对照组;2016年7月至12月采用PDCA护理管理模式,共180例,设为为观察组,对两组患者术后1月的护理满意度调查表的结果进行比较。结果 实施PDCA护理管理模式后患者在护理态度、专业技能以及健康宣教等方面满意度明显提高,与对照组比较差异有统计学意义(P<0.05)。结论 PDCA护理管理模式能有效提高护理质量,降低护理差错,提高患者对护理工作的满意度。     

Retracted Article: Chrysin attenuates myocardial ischemia–reperfusion injury by inhibiting myocardial inflammation

The aim of this study was to investigate the effects of chrysin (CH) on myocardial ischemia–reperfusion injury. Cytokines were reduced by CH in coronary artery occlusion-induced rats and also in H9C2 cells. The ST segment was also restored by CH. Triphenyltetrazolium chloride (TTC) staining and pathological analysis showed that CH could alleviate myocardial injury. Results in H9C2 cells showed that CH improved heart injury in hypoxia/reoxygenation (H/R) of H9C2 cells. In addition, the expressions of the HMGB1-related inflammation pathway in rats and H9C2 cells were significantly decreased by CH. The present study shows the protective effects of CH on myocardial injury via inflammation.

The aim of this study was to investigate the effects of chrysin (CH) on myocardial ischemia–reperfusion injury.     

北京三家医院患儿家长抗生素知识的调查

目的：通过对患儿家长抗生素知识的调查,了解他们对抗生素知识的掌握情况。方法随机选取2011年8~10月在北京三家医院就诊的1500名患儿家长,进行有关抗生素知识的问卷调查,回收有效回卷1416份。结果被调查者中46.00%知道细菌感染时要用抗生素,34.20%认为病毒感染要用抗生素。儿童普通伤风感冒(鼻塞、流涕及打喷嚏)时,认为需要使用抗生素的人占16.83%,一般咽炎或扁桃体炎(非化脓性)时该比例为36.92%,气管炎时为51.13%,肺炎时为68.90%。男性家长与女性家长答题的正确率分别为41.27%、42.55%,两者相比无明显差异(Χ2=40.059,P=0.021)。三级医院与二级医院患儿家长的答题正确率分别为43.44%、40.52%。两者相比差异有显著性(Χ2=82.969,P<0.01)。结论目前抗生素仍存在一定程度滥用情况,患儿家长对于抗生素应用指征认知不足,需进一步加强对于患儿家长抗生素知识的教育工作。     

医药中抗坏血酸检测方法研究

抗坏血酸即维生素C,广泛存在于食品、人体体液、组织及药品中,它参与体内一系列物质的代谢过程及氧化还原反应。因此,建立快速、准确地检测抗坏血酸含量的方法是全世界研究者关注的课题。常用的检测方法有分光光度法、荧光法、化学发光法、高效液相色谱法、电化学法和滴定法等,现对近几年有关抗坏血酸检测方法的研究作一综述。