首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2852866篇
  免费   259847篇
  国内免费   15780篇
耳鼻咽喉   40042篇
儿科学   86016篇
妇产科学   71325篇
基础医学   464795篇
口腔科学   76180篇
临床医学   258405篇
内科学   496616篇
皮肤病学   83961篇
神经病学   249536篇
特种医学   111681篇
外国民族医学   108篇
外科学   460063篇
综合类   91132篇
现状与发展   92篇
一般理论   2050篇
预防医学   231294篇
眼科学   65819篇
药学   193361篇
  23篇
中国医学   9814篇
肿瘤学   136180篇
  2022年   23008篇
  2021年   55387篇
  2020年   37071篇
  2019年   58271篇
  2018年   72417篇
  2017年   55858篇
  2016年   61556篇
  2015年   76332篇
  2014年   112994篇
  2013年   177700篇
  2012年   75051篇
  2011年   71433篇
  2010年   115066篇
  2009年   122642篇
  2008年   59026篇
  2007年   58814篇
  2006年   71447篇
  2005年   65803篇
  2004年   67628篇
  2003年   58928篇
  2002年   48902篇
  2001年   80073篇
  2000年   71268篇
  1999年   76583篇
  1998年   64089篇
  1997年   62218篇
  1996年   58977篇
  1995年   54395篇
  1994年   48186篇
  1993年   45062篇
  1992年   49557篇
  1991年   46208篇
  1990年   42921篇
  1989年   43404篇
  1988年   40079篇
  1987年   38925篇
  1986年   36741篇
  1985年   37401篇
  1984年   37013篇
  1983年   34742篇
  1982年   37623篇
  1981年   35701篇
  1980年   33708篇
  1979年   28053篇
  1978年   27404篇
  1977年   26181篇
  1976年   23258篇
  1975年   21239篇
  1974年   20180篇
  1973年   19219篇
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
81.
Maternal and Child Health Journal - Early life exposures can have an impact on a child’s developmental trajectory and children born late preterm (34–36 weeks gestational age)...  相似文献   
82.
83.
84.
Troppmair  Teresa  Egger  J.  Krösbacher  A.  Zanvettor  A.  Schinnerl  A.  Neumayr  A.  Baubin  M. 《Der Anaesthesist》2022,71(4):272-280
Die Anaesthesiologie - Die Qualität eines Rettungssystems zeichnet sich auch durch den effizienten Einsatz seiner personellen und Fahrzeugressourcen aus. So können im berechtigten Fall...  相似文献   
85.
86.
Cutaneous leiomyomas are rare benign smooth‐muscle tumors. These lesions are distinguished based on their cell of origin and are subclassified as pilar leiomyoma, angioleiomyoma, and genital‐type leiomyoma. Nipple leiomyoma is the least common genital‐type leiomyoma, arising from the dartoic muscle cell of the nipple. Histologic examination of the lesion is necessary for definitive diagnosis, and these uncommon tumors can pose a diagnostic challenge. We describe herein a series of six nipple leiomyomas with a spectrum of histologic appearances.  相似文献   
87.
Introduction: The Hedgehog (HH) pathway constitutes a collection of signaling molecules which critically influence embryogenesis. In adults, however, the HH pathway remains integral to the proliferation, maintenance, and apoptosis of adult stem cells including hematopoietic stem cells.

Areas covered: We discuss the current understanding of the HH pathway as it relates to normal hematopoiesis, the pathology of acute myeloid leukemia (AML), the rationale for and data from combination therapies including HH pathway inhibitors, and ultimately the prospects that might offer promise in targeting this pathway in AML.

Expert opinion: Efforts to target the HH pathway have been focused on impeding this disposition and restoring chemosensitivity to conventional myeloid neoplasm therapies. The year 2018 saw the first approval of a HH pathway inhibitor (glasdegib) for AML, though for an older population and in combination with an uncommonly-used therapy. Several other clinical trials with agents targeting modulators of HH signaling in AML and MDS are underway. Further study and understanding of the interplay between the numerous aspects of HH signaling and how it relates to the augmented survival of AML will provide a more reliable substrate for therapeutic strategies in patients with this poor-risk disease.  相似文献   

88.
ABSTRACT

Objective: Dry eye is reported to be associated with several neurological diseases. The aim of this study is to evaluate the patients with hemiplegia after stroke for dry eye and compare their results with a control group.

Materials and methods: Forty-five patients with hemiplegia and 45 individuals as the control group were included in the study. Tear function tests (Schirmer and tear breakup time) and a dry eye questionnaire for dry eye symptoms (ocular surface disease index) were performed and the results of the two groups were compared.

Results: Schirmer test results were significantly lower in the post-stroke hemiplegia group compared to the control group (11.3 ± 8.2 mm and 20.6 ± 11.6 mm, respectively, p < .001). Tear breakup time results were significantly lower in the post-stroke hemiplegia group compared to the control group (7.9 ± 3.1 s and 12.1 ± 4.3 s, respectively, p < .001). Ocular surface disease index scores were not significantly different between hemiplegia and control groups (21.6 ± 20.0 and 19.8 ± 13.9, respectively, p = .635). Schirmer scores lower than 10 mm (60% and 30%, p < .001) and tear breakup time results lower than 10 s (65.6% and 28.9%, p < .001) were also higher in the hemiplegia group compared to control group.

Conclusion: We found lower Schirmer test and tear breakup time results and similar OSDI scores in hemiplegia patients compared to controls. Hemiplegia patients may have dry eye without typical symptoms. This should be taken into consideration in the follow-up and rehabilitation of post-stroke hemiplegia patients.  相似文献   
89.
Introduction: Percutaneous renal mass biopsy has evolved over the last decade with improvements on previous pitfalls including low tissue yield, high non-diagnostic rates, and complications. As understanding of tumor biology and natural history of renal cortical neoplasms has improved, percutaneous renal mass biopsy is poised to have an expanding role in an area characterized by individualized management and refined risk stratification.

Areas covered: This review summarizes the evolution of renal mass biopsy to its current state with respect to outcomes, indications, and clinical guidelines.

Expert opinion: With improved understanding of differential biological potential of renal cortical neoplasms combined with technical improvements in diagnostic yield and accuracy, utilization of renal mass biopsy is becoming an important adjunct to patient care in a broad range of clinical scenarios, including active surveillance, thermal ablation, and use of primary systemic therapy in localized and advanced settings.  相似文献   

90.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号