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51.

Background

The surgical approach in total hip arthroplasty (THA) is often based on surgeon preference and local traditions. The anterior muscle-sparing approach has recently gained popularity in Europe. We tested the hypothesis that patient satisfaction, pain, function, and health-related quality of life (HRQoL) after THA is not related to the surgical approach.

Patients

1,476 patients identified through the Norwegian Arthroplasty Register were sent questionnaires 1–3 years after undergoing THA in the period from January 2008 to June 2010. Patient-reported outcome measures (PROMs) included the hip disability osteoarthritis outcome score (HOOS), the Western Ontario and McMaster Universities osteoarthritis index (WOMAC), health-related quality of life (EQ-5D-3L), visual analog scales (VAS) addressing pain and satisfaction, and questions about complications. 1,273 patients completed the questionnaires and were included in the analysis.

Results

Adjusted HOOS scores for pain, other symptoms, activities of daily living (ADL), sport/recreation, and quality of life were significantly worse (p < 0.001 to p = 0.03) for the lateral approach than for the anterior approach and the posterolateral approach (mean differences: 3.2–5.0). These results were related to more patient-reported limping with the lateral approach than with the anterior and posterolateral approaches (25% vs. 12% and 13%, respectively; p < 0.001).

Interpretation

Patients operated with the lateral approach reported worse outcomes 1–3 years after THA surgery. Self-reported limping occurred twice as often in patients who underwent THA with a lateral approach than in those who underwent THA with an anterior or posterolateral approach. There were no significant differences in patient-reported outcomes after THA between those who underwent THA with a posterolateral approach and those who underwent THA with an anterior approach.The approach used for total hip arthroplasty (THA) is often based on the surgeon’s preference and local traditions. In 2011, 7,360 primary THAs were reported to the Norwegian Arthroplasty Register (NAR) (Norwegian Arthroplasty Register Annual Report 2012). A lateral approach was used in 53% of the operations, the posterolateral approach in 28%, and an anterior approach in 16%. Anterior muscle-sparing approaches have gained popularity because it has been argued that patients with such surgical approaches have less pain, shorter length of stay, and shorter rehabilitation time. These are short-term effects (Rodriguez et al. 2014), and the long-term effects are not well documented.The anterior approaches used in Norway are either a modified Smith-Petersen approach (Smith-Petersen 1949, Judet and Judet 1950) or an anterolateral Watson-Jones approach (Watson-Jones 1936). These may have a longer learning curve (Greidanus et al. 2013) and a higher incidence of early revision (Spaans et al. 2012, Lindgren et al. 2012). The lateral approach (Hardinge 1982) divides the anterior portion of gluteus medius and minimus. Muscular-tendon suture or osteosuture is used to reinsert the tendon into the trochanteric area. This approach has been blamed for increasing the risk of damage to the superior gluteal nerve and to the gluteus medius muscle (Jolles and Bogoch 2006, Arthursson et al. 2007, Khan and Knowles 2007).The posterolateral approach involves division of the piriformis, obturator internus, and gemelli tendons (Pellicci et al. 1998). This approach is considered to have less effect on gait since the abductor muscles are not dissected (Shaw 1991, Hedlundh et al. 1995), but it has been associated with an increased risk of dislocations, with risk of injury to the sciatic nerve. More recent studies have shown that use of larger femoral head sizes can markedly reduce the dislocation rate (Amlie et al. 2010, Bistolfi et al. 2011, Ho et al. 2012).We compared the different approaches with regard to patient satisfaction, pain, function, and HRQoL after primary THA.  相似文献   
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OBJECTIVE: Knowledge of the history of our surgical specialty may broaden our viewpoint for everyday practice. We illustrate the scientific progress made in medieval times relevant to the vascular system and blood circulation, progress made despite prevailing religious and philosophical dogma. METHODS: We located all articles concerning vascular knowledge and historical reviews in databases such as MEDLINE, EMBASE and the database of abstracts of reviews (DARE). We also explored the database of the register from the French National Library, the French Medical Inter-University (BIUM), the Italian National Library and the French and Italian Libraries in the Vatican. All data were collected and analysed in chronological order. RESULTS: Medieval vascular knowledge was inherited from Greek via Byzantine and Arabic writings, the first controversies against the recognized vascular schema emanating from an Arabian physician in the 13th century. Dissection was forbidden and clerical rules instilled a fear of blood. Major contributions to scientific progress in the vascular field in medieval times came from Ibn-al-Nafis and Harvey. CONCLUSION: Vascular specialists today may feel proud to recall that once religious dogma declined in early medieval times, vascular anatomic and physiological discoveries led the way to scientific progress.  相似文献   
54.
Bronchial responsiveness in a Norwegian community   总被引:11,自引:0,他引:11  
Bronchial responsiveness to methacholine was examined in a Norwegian general population sample (n = 490) 18 to 73 yr of age. Altogether, 20 and 6% of the sample had PC20 less than or equal to 32 mg/ml and PC20 less than or equal to 8 mg/ml, respectively. The relationship of bronchial responsiveness to the following potential predictors were examined: sex, age, smoking habits, airway caliber (FEV1), FEV1 percent predicted (%FEV1), urban-rural area of residence, occupational airborne exposure in present job, and total serum IgE. After adjusting for age and FEV1, the odds ratio for PC20 less than or equal to 32 mg/ml was higher for men than for women in smokers and in ex-smokers, but did not vary by sex in nonsmokers, the adjusted odds ratio for PC20 less than or equal to 32 mg/ml in male compared with female smokers being 8.4 (95% Cl: 2.5-37.4). Irrespective of smoking status the sex- and FEV1-adjusted odds ratio for PC20 less than or equal to 32 mg/ml fell with increasing age. For every 10-yr increase in age the adjusted odds ratio for PC20 less than or equal to 32 mg/ml methacholine in nonsmokers decreased by 2.0 (95% Cl: 1.3-3.3). Also FEV1 and %FEV1 were predictors of PC20 less than or equal to 32 mg/ml after adjusting for sex and age irrespective of smoking status. Bronchial responsiveness (PC20 less than or equal to 8 mg/ml) was more prevalent in rural than in urban areas, the adjusted odds ratio being 2.5 (95% Cl: 1.1-5.9) for bronchial responsiveness in rural compared with urban residents after adjusting for sex, age, smoking habits, and FEV1.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   
55.
The aim of this study was to establish the relationship between the occurrence of a surgical site infection (SSI) and the presence of a central venous catheter-related infection (CVCRI). The Department of Thoracic and Cardiovascular Surgery, University Hospital, Rouen, has carried out a prospective epidemiological survey of all nosocomial infections (pneumonia, SSI and CVCRI) since 1997. The study group included all consecutive patients who underwent cardiac surgery over a 10-year period from 1997 to 2007. A nested case–control study was conducted to identify the risk factors for SSI after CVCRI. Cases were patients with SSI after CVCRI and controls were randomized from patients who presented with CVCRI not followed by SSI. In total, 7557 patients were included and 133 SSIs (1.7%) were identified. The rate of superficial SSI was 0.7% [95% confidence interval (CI): 0.5–0.9] and of mediastinitis was 1.0% (95% CI: 0.8–1.2). Among the 133 cases of SSI, 12 (9.0%; 95% CI: 5.0–14.8) occurred after a CVCRI with identical micro-organisms. CVCRI [adjusted odds ratio (aOR): 5.2; 95% CI: 3.2–8.5], coronary artery bypass grafting (aOR: 2.9; 95% CI: 1.6–5.2), and obesity (aOR: 11.4; 95% CI: 1.0–130.1) were independent factors associated with SSI. The new finding of this study is that patients with CVCRI were 5.2 times more likely to develop SSI compared to patients without CVCRI.  相似文献   
56.
BACKGROUND: In our population-based study of pregnancy outcome in women with rheumatic disease we based our assessment on the Medical Birth Registry of Norway (MBRN). We evaluated the MBRN as a source of data for such epidemiologic research by assessing the validity of a diagnosis of rheumatic disease in the MBRN against a gold standard. The validity may also be interpreted as a quality indicator, reflecting an obstetrician's attention to rheumatic diseases in pregnancy. METHODS: Using the mother's national identification number the MBRN was linked with local hospital databases (gold standard), which contained data of mothers with rheumatic disease. The sensitivity of the MBRN was calculated as the proportion of all cases registered locally with a diagnosis of rheumatic disease notified to the MBRN. The correctness of type differentiation was calculated as the proportion of all cases notified to the MBRN that was correct with respect to the type of rheumatic disease. RESULTS: Among 169 mothers, 149 had a diagnosis in the MBRN, representing a sensitivity of 88.2%. Altogether, 97.3% of the diagnoses (145/149) were correct with respect to the type of rheumatic disease. CONCLUSION: Taken in to consideration the limitations of the study, namely the small numbers studied, we assume a rather high validity of rheumatic disease diagnoses in the MBRN, probably reflecting a high level of attention in the obstetric care for these patients.  相似文献   
57.
PURPOSE: Female athletes often demonstrate changes in cardiac dimensions that are less prominent than in male athletes, and results from longitudinal studies are conflicting. The atrioventricular plane displacement (AVPD) in the heart is used as an index of left ventricular systolic function with the assumption that it is a more sensitive method for measuring myocardial contractility compared with left ventricular ejection fraction. The aim of the present study was to determine the effect of a short period of endurance training on cardiac dimensions in sedentary female subjects and to measure the AVPD at rest and during submaximal workload. METHODS: Twelve sedentary female subjects (21.9 +/- 1.3 yr, 168.8 +/- 3.5 cm, 64.0 +/- 6.6 kg, and 42.6 +/- 2.9 mL x kg(-1) x min(-1) in maximal oxygen uptake) were examined with echocardiography before and after a period of interval training (varying from 2 to 5 min at 90-95% of maximal heart rate, 3 d x wk(-1), 8 wk). RESULTS: Maximal oxygen uptake increased by 18% to 50.4 +/- 3.1 mL x kg(-1) x min(-1) (P < 0.001). Left ventricular mass increased from 123.9 to 139.2 g (P = 0.007). There was a significant increase in posterior wall thickness but no change in cavity size. The AVPD did not change at rest but increased significantly from 15.6 to 17.6 mm (P < 0.001) during exercise at 85-90% of maximal heart rate. CONCLUSION: This study shows that a short period of aerobic endurance training induces changes in the female heart, both in cardiac dimensions at rest and in left ventricular systolic function at submaximal workload. AVPD during submaximal exercise discriminate well between the untrained and trained healthy heart.  相似文献   
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OBJECTIVE: To describe the clinical features and hospitalization rates of American Indian children with full or incomplete fetal alcohol syndrome (FAS). STUDY DESIGN: Two retrospective case-control studies were conducted of Northern Plains American Indian children with presumed FAS identified from 1981 to 1993 by using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM), code 760.71. Children who had full or incomplete FAS were compared with each other and with children who did not have FAS. RESULTS: Compared with the control children, the 43 children with FAS and the 35 children with incomplete FAS had more facial dysmorphology, growth deficiency, central nervous system dysfunction, and muscular problems and were hospitalized more frequently with otitis media, pneumonia, FAS, dehydration, and anemia. Case children were hospitalized more days than were control children. Case children were removed from their homes and placed in foster care more often than were control children. CONCLUSIONS: Children with full or incomplete FAS had many health, learning, and social needs. Health care providers and community programs should identify the needs of these children and offer optimal services to meet those needs.  相似文献   
60.
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