全文获取类型
收费全文 | 529489篇 |
免费 | 28231篇 |
国内免费 | 493篇 |
专业分类
耳鼻咽喉 | 6681篇 |
儿科学 | 16948篇 |
妇产科学 | 12537篇 |
基础医学 | 92613篇 |
口腔科学 | 12346篇 |
临床医学 | 48500篇 |
内科学 | 95447篇 |
皮肤病学 | 11868篇 |
神经病学 | 34014篇 |
特种医学 | 19756篇 |
外国民族医学 | 53篇 |
外科学 | 78069篇 |
综合类 | 7612篇 |
现状与发展 | 2篇 |
一般理论 | 107篇 |
预防医学 | 38535篇 |
眼科学 | 11940篇 |
药学 | 41408篇 |
1篇 | |
中国医学 | 1126篇 |
肿瘤学 | 28650篇 |
出版年
2021年 | 3892篇 |
2018年 | 5733篇 |
2017年 | 4131篇 |
2016年 | 4869篇 |
2015年 | 5362篇 |
2014年 | 7114篇 |
2013年 | 10499篇 |
2012年 | 15574篇 |
2011年 | 17391篇 |
2010年 | 9956篇 |
2009年 | 8823篇 |
2008年 | 15712篇 |
2007年 | 17443篇 |
2006年 | 16941篇 |
2005年 | 16259篇 |
2004年 | 15880篇 |
2003年 | 15261篇 |
2002年 | 14782篇 |
2001年 | 22428篇 |
2000年 | 22972篇 |
1999年 | 18919篇 |
1998年 | 5232篇 |
1997年 | 4364篇 |
1996年 | 4397篇 |
1995年 | 4124篇 |
1992年 | 14415篇 |
1991年 | 15819篇 |
1990年 | 15954篇 |
1989年 | 15629篇 |
1988年 | 14314篇 |
1987年 | 14203篇 |
1986年 | 13178篇 |
1985年 | 12690篇 |
1984年 | 9399篇 |
1983年 | 8001篇 |
1982年 | 4178篇 |
1979年 | 8940篇 |
1978年 | 6383篇 |
1977年 | 5151篇 |
1976年 | 5507篇 |
1975年 | 6614篇 |
1974年 | 7421篇 |
1973年 | 7161篇 |
1972年 | 6599篇 |
1971年 | 6310篇 |
1970年 | 5887篇 |
1969年 | 5467篇 |
1968年 | 5161篇 |
1967年 | 4621篇 |
1966年 | 3963篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
111.
112.
113.
K. Dahan V. Audard F. Roudot-Thoraval D. Desvaux M. Abtahi H. Mansour M. Kumal P. Lang P. Grimbert 《American journal of transplantation》2006,6(7):1725-1730
The clinical outcome and appropriate management for patients showing 'borderline changes' on allograft biopsy after renal transplantation is still controversial. In an attempt to identify predictive factors of clinical outcome of patients with such lesions, we reviewed the clinical course of 91 patients with borderline changes. Multivariate analysis revealed significant and independent effects of histological stage (i + t < or = or > 2) and time to borderline changes (< or = or > 3 months after transplant) on serum creatinine levels at 1 year from borderline changes episodes (respectively, p = 0.04 and p = 0.02) and only a significant effect of time to borderline changes on serum creatinine levels at 2 years (p = 0.005). Renal function at 1 year and 2 years as 5- and 8-year graft survival were not significantly different in the group of patients treated with antirejection therapy (T group, n = 49) compared with the untreated group (UT group, n = 42). This study strongly suggests that borderline changes with histological score (i + t) > 2 and late episodes of borderline changes should be considered to be of poor prognosis. 相似文献
114.
115.
In rare cases the usage of the internal thoracic vessels as recipient vessels in reconstructive surgery of the head and neck region with free tissue transfer is a challenging but valid alternative if local recipient vessels are unusable. 相似文献
116.
Parupudi V J Sriram Guduru V Rao Nageshwar D Reddy 《Indian journal of gastroenterology》2006,25(1):39-41
Endoscopic clips have been used mainly for control of gastrointestinal (GI) bleeding and occasionally for closure of GI perforations. However, closure of spontaneous esophageal perforation (Boerhaave's syndrome) by clipping has not been reported. We described successful non-surgical closure of spontaneous esophageal perforation by endoscopic clipping in a patient with bilateral pyopneumothorax and septicemia. 相似文献
117.
118.
I García-Rubio C Martínez-Cócera T Robledo Echarren S Vázquez Cortés 《Journal of investigational allergology & clinical immunology》2006,16(4):264-265
Eye drops contain several ophthalmic medications which can produce allergic reactions. We report the case of a patient with contact dermatitis from neomycin and a probable fixed exanthema after parenteral administration of tobramycin who tolerated topical tobramycin and other aminoglycosides. 相似文献
119.
José Luis R Martin Víctor Pérez Montse Sacristán Fernando Rodríguez-Artalejo Cristóbal Martínez Enric Alvarez 《European psychiatry》2006,21(1):11-20
OBJECTIVE: To assess antipsychotic medication in the treatment of schizophrenia, based on trial drop-out rates. METHOD: The studies included were randomised controlled trials that compared any of the four clinically best-established atypical antipsychotics (quetiapine, olanzapine, risperidone or clozapine) against either of two typical antipsychotics regarded as the gold standard (haloperidol or chlorpromazine). RESULTS: Meta-analysis indicated less risk of all-cause patient withdrawal from atypical medication trials where dosage was flexible, in both the short, relative risk (RR) 0.70 (95% CI 0.64-0.76), P<0.00001, and long term, RR 0.72 (0.65-0.80), P<0.00001. Similar results were observed for withdrawal due to adverse events, RR: 0.54 (0.41-0.72), P<0.0001. Nevertheless, the favourable effects of atypical medication disappeared in trials relying on fixed dosage. CONCLUSIONS: We detected a significant positive effect in terms of the outcome of treatment discontinuation for atypical versus typical medication, though only where the use of flexible rather than fixed doses (closer to an experimental control situation) was possible. 相似文献
120.
Detailed pathological changes of human lumbar facet joints L1–L5 in elderly individuals 总被引:4,自引:1,他引:3
Facet joints play an important role in intervertebral load transmission and are crucial for rotational kinematics. Clinically, the role of facet joints as a possible source of low back pain is seen as controversial and at present is not sufficiently investigated. In this study, human lumbar facet (zygapopyhysial) joints from donors with advanced age were analyzed macroscopically, for degenerative changes. The aim was to determine the extent and morphology of degenerative changes in these joints. Lumbar facet joints (L1–L5) of 32 donors were studied (mean age 80.1±11.2 years). Joint capsules were carefully removed and joint surfaces (5 zones) examined using magnifying glasses and probes. In the result, the majority of facet joints showed cartilage defects of varying extent. Defects were located mostly at the margins of the articular surface, the central zone being relatively well preserved. Defect localization was different between superior (most cartilage defects in superior zone) and inferior (most defects inferiorly) facets. Further, defects were more severe caudal (level of L5) and in older persons. Osteophytes were present in up to 30%, located mostly at the latero-dorsal enthesis of the joint capsule on the superior facet. In conclusion, most margins of the articular facets are subject to degenerative changes in the lumbar spine of elderly persons, the topographical pattern being different in superior and inferior facets. This observation can be explained by the segmental motion patterns during extension/flexion movements of the facets. Sometimes, due to the marginal extension, it is obvious that not all changes can be assessed by CT or MRI. 相似文献