全文获取类型
收费全文 | 651篇 |
免费 | 63篇 |
国内免费 | 66篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 56篇 |
妇产科学 | 10篇 |
基础医学 | 92篇 |
口腔科学 | 27篇 |
临床医学 | 112篇 |
内科学 | 130篇 |
皮肤病学 | 1篇 |
神经病学 | 63篇 |
特种医学 | 101篇 |
外科学 | 31篇 |
综合类 | 35篇 |
预防医学 | 28篇 |
眼科学 | 1篇 |
药学 | 68篇 |
中国医学 | 2篇 |
肿瘤学 | 20篇 |
出版年
2021年 | 8篇 |
2020年 | 6篇 |
2019年 | 8篇 |
2018年 | 7篇 |
2017年 | 8篇 |
2016年 | 8篇 |
2015年 | 14篇 |
2014年 | 7篇 |
2013年 | 15篇 |
2012年 | 15篇 |
2011年 | 28篇 |
2010年 | 10篇 |
2009年 | 21篇 |
2008年 | 17篇 |
2007年 | 55篇 |
2006年 | 29篇 |
2005年 | 15篇 |
2004年 | 17篇 |
2003年 | 15篇 |
2002年 | 25篇 |
2001年 | 23篇 |
2000年 | 18篇 |
1999年 | 14篇 |
1998年 | 29篇 |
1997年 | 28篇 |
1996年 | 27篇 |
1995年 | 21篇 |
1994年 | 21篇 |
1993年 | 11篇 |
1992年 | 13篇 |
1991年 | 8篇 |
1990年 | 20篇 |
1989年 | 18篇 |
1988年 | 21篇 |
1987年 | 17篇 |
1986年 | 18篇 |
1985年 | 20篇 |
1984年 | 12篇 |
1983年 | 11篇 |
1982年 | 12篇 |
1981年 | 13篇 |
1980年 | 11篇 |
1979年 | 13篇 |
1978年 | 14篇 |
1977年 | 5篇 |
1976年 | 8篇 |
1975年 | 14篇 |
1972年 | 2篇 |
1971年 | 3篇 |
1966年 | 2篇 |
排序方式: 共有780条查询结果,搜索用时 15 毫秒
11.
12.
Kernohan G Trainor B Mollan R Normand C 《The International journal of health planning and management》1991,6(3):229-233
Early treatment for congenital dislocation of the hip is usually simple and inexpensive. However, if the disease is not detected by 6 months of age, treatment is often complicated and expensive. We evaluated the potential cost-saving of screening, by examining the costs in 36 late cases born in 1980 and found an average cost of pounds 6,674 per case for treatment to this date. This amount could justifiably be spent on each case detected in an effective screening programme. 相似文献
13.
Frequency of the ATM IVS10-6T→G variant in Australian multiple-case breast cancer families 下载免费PDF全文
14.
Joe Iwanaga Vishram Singh Aiji Ohtsuka Youngil Hwang Hee‐Jin Kim Janusz Mory Kumar Satish Ravi Domenico Ribatti Paul A. Trainor Jos Ramn Saudo Nihal Apaydin Gülgün engül Kurt H. Albertine Jerzy A. Walocha Marios Loukas Fabrice Duparc Friedrich Paulsen Mariano Del Sol Philip Adds Ahmed Hegazy R. Shane Tubbs 《Clinical anatomy (New York, N.Y.)》2021,34(1):2-4
Research within the anatomical sciences often relies on human cadaveric tissues. Without the good will of these donors who allow us to use their bodies to push forward our anatomical knowledge, most human anatomical research would come to a standstill. However, many research papers omit an acknowledgement to the donor cadavers or, as no current standardized versions exist, use language that is extremely varied. To remedy this problem, 20 editors‐in‐chiefs from 17 anatomical journals joined together to put together official recommendations that can be used by authors when acknowledging the donor cadavers used in their studies. The goal of these recommendations is to standardize the writing approach by which donors are acknowledged in anatomical studies that use human cadaveric tissues. Such sections in anatomical papers will not only rightfully thank those who made the donation but might also encourage, motivate, and inspire future individuals to make such gifts for the betterment of the anatomical sciences and patient care. 相似文献
15.
The need for effective youth suicide prevention is uncontested, and is particularly urgent for Indigenous populations. The Indigenous youth suicide rates in some North American communities can be 18 times greater than for other young people. Despite the clear need, evidence in support of Indigenous youth suicide prevention strategies remain mixed. The most common approach to youth suicide prevention – gatekeeper training – may have limited effects in Indigenous communities. Based on recent work undertaken with Indigenous leaders in rural Alaska, we describe culturally grounded, practical alternatives that may be more effective for Indigenous communities. We highlight the ways in which research informed, grassroots interventions can address cultural, practical and systemic issues that are relevant when addressing risks for suicide on a community level. Built on a transactional-ecological framework that gives consideration to local contexts, culture-centric narratives and the multiple, interacting conditions of suicide, the innovative approach described here emphasizes community and cultural protective factors in Indigenous communities, and extends typical suicide prevention initiatives in ways that have important implications for other ethnically diverse communities. 相似文献
16.
Singh Ayesha Coulter Amanda R. Trainor Patrick J. Singam Narayana Sarma V. Aladili Bahjat N. Amraotkar Alok R. Owolabi Ugochukwu S. DeFilippis Andrew P. 《Journal of thrombosis and thrombolysis》2021,51(1):120-128
Journal of Thrombosis and Thrombolysis - Platelet activation and subsequent aggregation is a vital component of atherothrombosis resulting in acute myocardial infarction. Therefore, quantifying... 相似文献
17.
18.
19.
T.N. Hoa Tran Eamonn Trainor Toyoko Nakagomi Nigel A. Cunliffe Osamu Nakagomi 《Journal of clinical virology》2013,56(3):269-277
Noroviruses are a leading cause of epidemic and sporadic acute gastroenteritis worldwide. The development of sensitive molecular diagnostic techniques has revolutionized our understanding of norovirus epidemiology over the past two decades, but norovirus strain types associated with sporadic gastroenteritis remain poorly described. Therefore, we conducted a systematic review of studies performed after 2000 to clarify the genotypic distribution of noroviruses in children (≤18 years of age) with sporadic acute gastroenteritis. Genogroup GII norovirus was the most prevalent, accounting for 96% of all sporadic infections. GII.4 was the most prevalent genotype, accounting for 70% of the capsid genotypes and 60% of the polymerase genotypes, followed by the capsid genotype GII.3 (16%) and the polymerase genotype GII.b (14%). The most common ORF1/ORF2 inter-genotype recombinants were GII.b, GII.12, and GII.4 polymerase genotypes combined with the capsid genotype GII.3, accounting for 19% of all genotyped strains. The distribution of GII.4 variants over the last decade was dominated by successive circulation of GII.4/2002, GII.4/2004, GII.4/2006b, and GII.4/2008 with GII.4/2006b continuing to date. Genotypes GII.4 and GII.3 have predominated in children during the past decade; this is most notable in the global emergence of GII.4 variant noroviruses. As the burden of rotavirus disease decreases following the introduction of childhood immunization programs, the relative importance of norovirus in the etiology of acute childhood gastroenteritis will likely increase. In order for a successful norovirus vaccine to be developed, it should provide immunity against strains with capsid genotypes GII.4 and GII.3. 相似文献
20.
Association of GATA-1 and its cofactor Friend of GATA-1 (FOG-1) is essential for erythroid and megakaryocyte development. To assess functions of GATA-1-FOG-1 association during mouse development, we used the GATA-1 hematopoietic regulatory domain to generate transgenic mouse lines expressing a mutant GATA-1, which contains a substitution of glycine 205 for valine (V205G) that abrogates its association with FOG-1. We examined whether the transgenic expression of mutant GATA-1 rescues GATA-1 germ line mutants from embryonic lethality. In high-expressor lines we observed that the GATA-1(V205G) rescues GATA-1-deficient mice from embryonic lethality at the expected frequency, revealing that excess GATA-1(V205G) can eliminate the lethal anemia that is due to GATA-1 deficiency. In contrast, transgene expression comparable to the endogenous GATA-1 level resulted in much lower frequency of rescue, indicating that the GATA-1-FOG-1 association is critical for normal embryonic hematopoiesis. Rescued mice in these analyses exhibit thrombocytopenia and display dysregulated proliferation and impaired cytoplasmic maturation of megakaryocytes. Although anemia is not observed under steady-state conditions, stress erythropoiesis is attenuated in the rescued mice. Our findings reveal an indispensable role for the association of GATA-1 and FOG-1 during late-stage megakaryopoiesis and provide a unique model for X-linked thrombocytopenia with inherited GATA-1 mutation. 相似文献