全文获取类型
收费全文 | 1211218篇 |
免费 | 89054篇 |
国内免费 | 3913篇 |
专业分类
耳鼻咽喉 | 17034篇 |
儿科学 | 31301篇 |
妇产科学 | 32270篇 |
基础医学 | 171157篇 |
口腔科学 | 36505篇 |
临床医学 | 117511篇 |
内科学 | 236711篇 |
皮肤病学 | 25437篇 |
神经病学 | 92170篇 |
特种医学 | 45956篇 |
外国民族医学 | 160篇 |
外科学 | 192103篇 |
综合类 | 26452篇 |
现状与发展 | 2篇 |
一般理论 | 287篇 |
预防医学 | 76542篇 |
眼科学 | 28843篇 |
药学 | 94097篇 |
4篇 | |
中国医学 | 3939篇 |
肿瘤学 | 75704篇 |
出版年
2019年 | 8581篇 |
2018年 | 13653篇 |
2017年 | 11107篇 |
2016年 | 12003篇 |
2015年 | 13531篇 |
2014年 | 18050篇 |
2013年 | 25247篇 |
2012年 | 32560篇 |
2011年 | 33994篇 |
2010年 | 20841篇 |
2009年 | 20209篇 |
2008年 | 32477篇 |
2007年 | 34348篇 |
2006年 | 34723篇 |
2005年 | 32915篇 |
2004年 | 31612篇 |
2003年 | 30273篇 |
2002年 | 29509篇 |
2001年 | 72660篇 |
2000年 | 74306篇 |
1999年 | 61860篇 |
1998年 | 15046篇 |
1997年 | 13148篇 |
1996年 | 12796篇 |
1995年 | 11929篇 |
1994年 | 10815篇 |
1993年 | 9922篇 |
1992年 | 45656篇 |
1991年 | 43276篇 |
1990年 | 41584篇 |
1989年 | 40639篇 |
1988年 | 36848篇 |
1987年 | 35876篇 |
1986年 | 33401篇 |
1985年 | 31710篇 |
1984年 | 22398篇 |
1983年 | 18858篇 |
1982年 | 9770篇 |
1979年 | 19557篇 |
1978年 | 13034篇 |
1977年 | 11241篇 |
1976年 | 9608篇 |
1975年 | 10556篇 |
1974年 | 12742篇 |
1973年 | 11984篇 |
1972年 | 11486篇 |
1971年 | 10897篇 |
1970年 | 10258篇 |
1969年 | 9705篇 |
1968年 | 8853篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
992.
Individual crystallins, urea-soluble and urea-insoluble proteins were isolated from the nucleus and cortex of types I-IV cataractous lenses and normal lenses. The levels of protein sulphydryls (P-SH), disulphides (S-S), as well as surface (F-SH) and buried (S-SH) in these proteins were determined by reaction with 5, 5'-dithiotris- (2-nitrobenzoic acid) or performic acid oxidation followed by amino acid analysis. During nuclear colour development there is a progressive decrease in the sulphydryl content of the crystallins. In the nuclei of advanced cataractous lenses, the P-SH decreases to 10% of the levels found in the normal nucleus. Similar but smaller changes take place in the cortex. No specific changes were found between the crystallins, with the exception of beta S crystallin. The cysteine remains constant in all lens types suggesting no higher oxidation products are formed. There is a significant shift in the distribution of cysteine in the nucleus of type III and IV lenses. Urea-insoluble proteins are the predominant species, accounting for about 70% of the total cysteine pool. This is consistent with the accumulation of modified insoluble polypeptides during senile nuclear cataract formation. 相似文献
993.
T D Mastro 《Annals of internal medicine》1987,106(1):173-174
994.
995.
A 68-year-old man had subacute cerebellar degeneration and a non-Hodgkin's lymphoma. Using an immunoblotting method, we found serum antibodies to rat cerebral 250-kd and 110-kd and cerebellar 110-kd acidic cytoplasmic proteins. The antibodies did not react unless the antigens were prepared soon after death with protease inhibitors. Two hundred fifty-kd and 110-kd proteins are minor components of soluble cytoplasmic proteins of the brain. The molecular weights differed from other soluble brain-specific proteins already characterized. 相似文献
996.
997.
998.
Localized primary (AL) amyloid tumor of the breast. Cytologic, histologic, immunocytochemical and ultrastructural observations 总被引:2,自引:0,他引:2
J F Silverman D J Dabbs H T Norris W J Pories J Legier S Kay 《The American journal of surgical pathology》1986,10(8):539-545
Two examples of localized primary amyloid tumor of the breast are presented, including one patient with metachronous bilateral lesions. Our findings and review of the literature indicate that this rare lesion occurs predominantly in elderly females and can be mammographically and clinically confused with carcinoma. Fine-needle aspiration biopsy can be a useful procedure to make a preliminary diagnosis. Congo red staining with prior potassium permanganate incubation confirmed the AL type of amyloid in our two cases; this might be the predominant type in the localized form involving the breast. Immunofluorescence studies demonstrated IgA, with kappa and lambda light-chain deposition within the amyloid foci in one case, and intracytoplasmic IgG with both light chains within plasma cells and amyloid deposits of the second case. Ultrastructural examination of one of the cases showed characteristic findings of straight, nonbranching fibrils of 4-9 nm, diagnostic of amyloid. From our findings and a review of the literature, we conclude that amyloid tumors of the breast can occur in three separate settings: secondary amyloidosis, systemic or multiple myeloma associated amyloidosis, and as a localized primary type having a benign course. 相似文献
999.
1000.