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131.
S S Sahu S K Parida C Sadanandane K Gunasekaran P Jambulingam P K Das 《Indian journal of malariology》1990,27(4):209-216
Anopheline breeding habitats were studied in two different geoclimatic zones. The vectors A. fluviatilis, A annularis and A. culicifacies breed in all types of habitats. Streams were most productive for the main vector, A. fluviatilis and breeding was intense during winter and early summer. In the rainy season, breeding occurred in terraced paddy fields. A. culicifacies were produced in large numbers in rivers in summer and in paddy fields in rainy and cold seasons. Considering the vastness of these breeding habitats, vector control measures by larviciding or any other bioenvironmental means will not be a feasible alternative even though house spraying poses serious problems in this area due to several reasons. The use of personal protection methods is suggested. 相似文献
132.
Studies were undertaken to determine whether nitric oxide (NO) is involved in induction of the prolactin surge on proestrus and in that induced by ovarian steroids in ovariectomized (ovx) rats, by using inhibitors of NO synthase, the enzyme that generates NO. Two week-ovariectomized rats were treated either with estradiol benzoate (EB, 30 μg/rat, s.c.) alone, or with EB and 2 days later with progesterone (P, 2 mg/rat, s.c.) to evoke a prolactin surge in the afternoon. Injections of the NO synthase inhibitor
methyl ester (40 mg/kg, s.c.) at 10.00, 12.00, and 14.00 h completely suppressed the steroid-induced prolactin surge in the afternoon. Similarly, another NO synthase inhibitor,
(100 mg/kg, s.c.), injected at 1000, 1200, and 1400 h on proestures suppressed prolactin and luteinizing hormone (LH) surges, but failed to alter the daily increase of corticosterone. These studies confirm our earlier report and show that NO is involved in the complex processes that initiate the afternoon prolactin and LH surges of proestrus. 相似文献
133.
Using a PCR‐based method, we detected Wolbachia in the Asian rice gall midge. Furthermore, results showed that all females across all biotypes are infected with Wolbachia. However, all male flies are not infected and show different infection frequency in different biotypes. We have also identified three mitotypes, in the rice gall midge, based on DraI restriction pattern of a portion of the 12S rRNA gene that was PCR amplified using primers specific to this gene. All the females and infected male flies had type 1 mtDNA while uninfected males showed only type 2 or 3 mtDNA. Inheritance patterns of mtDNA revealed the existence of a correlation between mtDNA type and Wolbachia infection in the Asian rice gall midge. Evidence for paternal inheritance of mtDNA in Wolbachia‐free gall midge is also presented. 相似文献
134.
Prediabetes occurs due to two basic defects--insulin resistance and/or beta-cell failure. An observation suggested that insulin resistance may be associated with essential hypertension. There are some thoughts to favour the argument that insulin resistant Individuals are at a higher risk to develop hypertension as compared to insulin sensitive individuals. Some pathophysiological causes which have been commonly observed and hypothesised are narrated in this article. Management of hypertension in prediabetes should include antihypertensives and therapeutic lifestyle modification. To manage hypertension in prediabetes one should think for dietary modification, reduced salt intake, physical activity, smoking cessation, use of statins and antihypertensives. 相似文献
135.
Breast Cancer Research and Treatment - 相似文献
136.
Kankshi Sahu Anumegha Gupta Alka Sharma Meenakshi Tiwari Ashutosh N. Pandey Shilpa Prasad 《Growth factors (Chur, Switzerland)》2018,36(1-2):41-47
In mammals, preovulatory oocytes are encircled by several layers of granulosa cells (GCs) in follicular microenvironment. These follicular oocytes are arrested at diplotene arrest due to high level of cyclic nucleotides from encircling GCs. Pituitary gonadotropin acts at the level of encircling GCs and increases adenosine 3′,5′-cyclic monophosphate (cAMP) and guanosine 3′,5′-cyclic monophosphate (cGMP) and activates mitogen-activated protein kinase 3/1 (MAPK3/1) signaling pathway. The MAPK3/1 disrupts the gap junctions between encircling GCs and oocyte. The disruption of gap junctions interrupts the transfer of cyclic nucleotides to the oocyte that results a drop in intraoocyte cAMP level. A transient decrease in oocyte cAMP level triggers maturation promoting factor (MPF) destabilization. The destabilized MPF finally triggers meiotic resumption from diplotene arrest in follicular oocyte. Thus, MAPK3/1 from GCs origin plays important role in gonadotropin-mediated meiotic resumption from diplotene arrest in follicular oocyte of mammals. 相似文献
137.
D. H. Phalke S. R. Patil A. L. Pharande M. C. Manna Asha Sahu Shamandeep Kaur 《Proceedings of the National Academy of Sciences, India. Section B.》2016,86(2):299-307
An investigation was carried out by conducting a field experiment at the farm of the Mahatma Phule Krishi Vidyapeeth (MPKV), Rahuri. The significant grain yield of soybean (37.5 q ha?1) and maize (49 q ha?1) were observed in the treatment receiving 100 % recommended doses of Nitrogen, Phosphorus and Potassium (NPK) + in situ compost of crop residues, pressmud compost (T6). After harvest of maize dehydrogenase activity, acid phosphatase, β-glucosidase and urease were significantly improved in T7 treatment as compared to other treatments. However, fluorescein diacetate activity and alkaline phosphatase were significantly greater in T6 treatment in post-harvest soil samples of maize. In the post-harvest soil of maize the bacterial and actinomycetes population were greater in the treatment receiving in situ decomposition of sugarcane crop residues + 100 % recommended dose of NPK (T3). The fungal population after harvest of maize was found maximum in treatment T7. The total organic carbon was significantly correlated with dehydrogenase (r = 0.65, P < 0.01), fluorescein diacetate (r = 0.71, P < 0.01), acid phosphatase (r = 0.66, P < 0.01), β-glucosidase (r = 0.65, P < 0.01), and urease (r = 0.57, P < 0.01). There was a significant correlation (r = 0.77, P < 0.01) between TOC and soybean yield, and between total organic carbon and maize yield (r = 0.98, P < 0.01). The result suggest that in situ recycling of sugarcane crop residues and the industrial wastes with suitable interventions like use of bioinoculum, phosphatic fertilizer and urea may help for improving better crop productivity and soil biological activities. 相似文献
138.
Hope Caughron Dennis Kim Norihiko Kamioka Stamatios Lerakis Altayyeb Yousef Aneesha Maini Shawn Reginauld Anurag Sahu Subhadra Shashidharan Maan Jokhadar Fred H. Rodriguez Wendy M. Book Michael McConnell Peter C. Block Vasilis Babaliaros 《JACC: Cardiovascular Interventions》2018,11(24):2495-2503
Objectives
This study compares 30-day, 1-year, and 3-year echocardiographic findings and clinical outcomes of transcatheter pulmonary valve-in-valve replacement (TPVR) and repeat surgical pulmonary valve replacement (SPVR).Background
In patients with adult congenital heart disease and previous pulmonary valve replacement (PVR) who require redo PVR, it is unclear whether TPVR or repeat SPVR is the preferred strategy.Methods
We retrospectively identified 66 patients (TPVR, n = 36; SPVR, n = 30) with bioprosthetic pulmonary valves (PVs) who underwent either TPVR or repeat SPVR at Emory Healthcare from January 2007 to August 2017.Results
The TPVR cohort had fewer men and more patients with baseline New York Heart Association (NYHA) functional class III or IV. There was no difference in mortality, cardiovascular readmission, or post-procedural PV reintervention at 30 days, 1 year, or 3 years. Post-procedural echocardiographic findings showed no difference in mean PV gradients between the TPVR and SPVR groups at 30 days, 1 year, or 3 years. In the TPVR cohort, there was less right ventricular dysfunction at 30 days (2.9% vs. 46.7%; p < 0.01), despite higher baseline NYHA functional class in the SPVR cohort.Conclusions
In patients with bioprosthetic PV dysfunction who underwent either TPVR or SPVR, there was no difference in mortality, cardiovascular readmission, or repeat PV intervention at 30 days, 1 year, or 3 years. Additionally, TPVR and SPVR had similar intermediate-term PV longevity, with no difference in PV gradients or PVR. The TPVR cohort also had less right ventricular dysfunction at 30 days despite a higher baseline NYHA functional classification. These intermediate-term results suggest that TPVR may be an attractive alternative to SPVR in patients with previous bioprosthetic surgical PVs. 相似文献139.
Kamal Kant Sahu Pankaj Malhotra Alka Khadwal Manupdesh Singh Sachdeva Prashant Sharma Neelam Varma Subhash Chander Varma 《Indian journal of hematology & blood transfusion》2015,31(4):460-465
Eosinophilia is rare in acute leukemia at presentation. Discrete reports and case studies in recent years have created significant interest in the field of “Acute leukemia with eosinophilia”. We herein present two cases of eosinophilia in association with acute lymphoblastic leukemia with brief review of literature in this field. First case is about 21-year-old female who presented with mediastinal mass along with leukocytosis and hypereosinophilia. On evaluation, she was found to have T cell acute lymphoblastic leukemia. After ruling out benign causes of eosinophilia, she was treated with modified BFM-90 protocol. Her eosinophilia resolved after 4 weeks of induction therapy. Second case is about 32-year-old male who was diagnosed as a case of mixed phenotype leukemia (B cell/myeloid type) along with severe eosinophilia. His hypereosinophilia finally resolved by week 16 of modified BFM-90 protocol. Diagnosing ALL is challenging when eosinophilia is the initial presentation. These two cases emphasize on the importance of considering ALL amongst one of the etiological causes of eosinophilia as delay in diagnosis endangers patient’s life at risk. Also eosinophilia per se is an independent poor risk factor, hence prompt diagnosis and early treatment is the key in all such cases. 相似文献
140.
Kamal Kant Sahu Ruchita Tyagi Arjun Datt Law Alka Khadwal Gaurav Prakash Arvind Rajwanshi Subhash Chander Varma Pankaj Malhotra 《Indian journal of hematology & blood transfusion》2015,31(4):466-471
Myeloid sarcoma is an extramedullary tumor seen most commonly in patients with acute myeloid leukemia and less frequently in chronic myeloid leukemia, myelodysplastic syndrome and rarely, in an isolated form without any other underlying malignancy. Malignant pleural effusion in hematological malignancies is rare when compared with solid tumors. We present an unusual case of myeloid sarcoma in which a mediastinal mass with pleural effusion was the initial presentation. A 27 year old gentleman presented with complaints of fever, chest pain and swelling in the anterior chest wall for 6 months. Examination revealed a lump measuring 5 × 5 cm on the left side of the chest wall. Hematological evaluation showed hemoglobin-14.2 g/dL, platelet count-233 × 109/L, TLC-117 × 106/L with normal differential counts. Contrast enhanced computerised tomography (CECT) confirmed the presence of a soft tissue mass in the superior mediastinum abutting against the chest wall. Core biopsy was suggestive of myeloid sarcoma and immunohistochemistry was positive for myeloperoxidase and negative for CD3, CD 20 and CD 23. Pleural fluid analysis showed the presence of malignant cells. Bone marrow examination did not show an excess of blasts. A final diagnosis of extramedullary myeloid sarcoma with malignant pleural effusion was made. The patient was given induction chemotherapy (3 + 7 regimen) with daunorubicin and cytosine arabinoside. Repeat CECT done on day 28 showed complete resolution of pleural effusion and significant reduction in the size of mediastinal mass. The patient has successfully completed three cycles of consolidation therapy following which there has been complete resolution of the mass. He remains asymptomatic on close follow up. 相似文献