全文获取类型
收费全文 | 860篇 |
免费 | 54篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 29篇 |
儿科学 | 46篇 |
妇产科学 | 21篇 |
基础医学 | 104篇 |
口腔科学 | 15篇 |
临床医学 | 98篇 |
内科学 | 176篇 |
皮肤病学 | 6篇 |
神经病学 | 29篇 |
特种医学 | 73篇 |
外国民族医学 | 1篇 |
外科学 | 113篇 |
综合类 | 36篇 |
预防医学 | 47篇 |
药学 | 61篇 |
中国医学 | 3篇 |
肿瘤学 | 71篇 |
出版年
2023年 | 3篇 |
2022年 | 13篇 |
2021年 | 15篇 |
2020年 | 14篇 |
2019年 | 26篇 |
2018年 | 20篇 |
2017年 | 21篇 |
2016年 | 18篇 |
2015年 | 8篇 |
2014年 | 29篇 |
2013年 | 33篇 |
2012年 | 39篇 |
2011年 | 32篇 |
2010年 | 40篇 |
2009年 | 28篇 |
2008年 | 21篇 |
2007年 | 34篇 |
2006年 | 29篇 |
2005年 | 31篇 |
2004年 | 28篇 |
2003年 | 36篇 |
2002年 | 17篇 |
2001年 | 23篇 |
2000年 | 22篇 |
1999年 | 28篇 |
1998年 | 37篇 |
1997年 | 28篇 |
1996年 | 30篇 |
1995年 | 26篇 |
1994年 | 22篇 |
1993年 | 15篇 |
1992年 | 23篇 |
1991年 | 14篇 |
1990年 | 15篇 |
1989年 | 11篇 |
1988年 | 17篇 |
1987年 | 12篇 |
1986年 | 14篇 |
1985年 | 10篇 |
1984年 | 7篇 |
1983年 | 7篇 |
1982年 | 4篇 |
1981年 | 5篇 |
1980年 | 3篇 |
1979年 | 6篇 |
1977年 | 4篇 |
1976年 | 3篇 |
1975年 | 2篇 |
1974年 | 2篇 |
1950年 | 1篇 |
排序方式: 共有929条查询结果,搜索用时 15 毫秒
61.
Shu-Tse Lai Chih-Hsing Hung Yi-Ming Hua Shih-Hsien Hsu Yuh-Jyh Jong Jau-Ling Suen 《Pediatrics international》2008,50(1):99-102
BACKGROUND: T-helper (Th) 2 cytokines are thought to mediate most of the allergic inflammatory responses associated with atopic asthma. But the Th1-related chemokine, interferon-inducible protein 10 (IP-10)/CXCL10, was the predominant chemokine measured during human allergic pulmonary late-phase reaction. The aim of the present study was to evaluate the role of Th1- and Th2- related chemokines in the pathogenesis of asthma exacerbation. METHODS: Plasma levels of the Th2-related C-C chemokine I-309 (CCL1), the Th1-related CXC chemokines IP-10, and the monokine induced by interferon-gamma (Mig)/CXCL9 were measured in patients with stable asthma. RESULTS: These results were compared to the results measured prior to, and after corticosteroid treatment, in patients who experienced asthma exacerbations. A significant increase in the plasma levels of IP-10 and Mig, but not I-309, were found in patients with an acute exacerbation in contrast to patients with stable asthma. Plasma levels of IP-10 and Mig were significantly higher in patients during an acute asthma exacerbation than during a subsequent convalescent period. CONCLUSIONS: The Th1-related CXC chemokines IP-10 and Mig may be useful inflammatory markers of asthma exacerbation in children. 相似文献
62.
63.
H Kaube YE Knight RJ Storer KL Hoskin A May PJ Goadsby 《Cephalalgia : an international journal of headache》1999,19(6):592-597
It remains an open question as to whether cortical spreading depression (CSD) is the pathophysiological correlate of the neurological symptoms in migraine with aura. In the experimental animal, CSD is an electrophysiological phenomenon mainly mediated via NMDA receptors. However, according to case reports in humans, visual aura in migraine can be alleviated by vasodilator substances, such as amyl nitrite and isoprenaline. There is also circumstantial evidence that brainstem nuclei (dorsal raphe nucleus and locus coeruleus) may play a pivotal role in the initiation of aura. In this study, CSD was elicited in alpha-chloralose anesthetized cats by cortical needle stab injury and monitored by means of laser Doppler flowmetry. Topical application of isoprenaline (0.1-1%) and amyl nitrite (0.05%) onto the exposed cortex had no effect on the elicitation or propagation of CSD. Also, after supracollicular transection, subsequent CSDs showed no differences in the speed of propagation and associated flow changes. We conclude from these data that--given CSD probably exists in humans during migraine--spreading neurological deficits during migraine aura are independent of brainstem influence and have a primarily neuronal rather than vascular mechanism of generation. 相似文献
64.
65.
66.
67.
Aileen W. K. Chan Albert Lee Lorna K. P. Suen Wilson W. S. Tam 《Quality of life research》2010,19(5):653-664
Purpose
This paper evaluates the effectiveness of a 3-month Tai chi Qigong (TCQ) program in promoting the psychosocial functional health of clients with chronic obstructive pulmonary disease (COPD) in Hong Kong. 相似文献68.
High-field surface coil magnetic resonance (MR) images were obtained of 12 ankles: two from healthy volunteers, seven from patients, and three from fresh cadavers. The cadaver ankles were sectioned in the coronal, sagittal, and axial planes for direct comparison with the MR images. Plain film confirmation of pathologic conditions was obtained in all patients, and five underwent arthroscopy or surgery, or both. MR imaging provided excellent delineation of ligaments and cartilaginous structures in all cases. 相似文献
69.
70.
Increments in platelet counts following the transfusion of platelets mismatched for crossreactive antigens were evaluated in 67 patients with broad alloimmunization to HLA antigens. The corrected increments following 100 HLA, A-matched and B1U- or B2U-matched transfusions were compared with the increments following 307 B1X- or B2X-matched transfusions. HLA-A3 platelets were tolerated poorly by A1 and A11 recipients, as were A1 and A11 by A3 recipients, B17 and BW21 by recipients in the B7 crossreactive group, B5 by B15 and B17 recipients, and B27 by recipients in the B5 crossreactive group. B12 and BW21, and B8 and B14 platelets were not tolerated bidirectionally. Antigens associated with good increments included A28 in A2 recipients, B18 and BW16 (C match) in recipients in the B5 crossreactive group, B5 in B18 recipients, BW22 and B7 in recipients in the B7 crossreactive group. A1 and A11 were transfused successfully bidirectionally. These observations suggest that some private antigens within crossreactive groups are more immunogenic than others and support the observation of others than B17 and BW21 are not in the B5 crossreactive group. 相似文献