全文获取类型
收费全文 | 5676篇 |
免费 | 387篇 |
国内免费 | 29篇 |
专业分类
耳鼻咽喉 | 64篇 |
儿科学 | 312篇 |
妇产科学 | 99篇 |
基础医学 | 722篇 |
口腔科学 | 182篇 |
临床医学 | 611篇 |
内科学 | 1261篇 |
皮肤病学 | 80篇 |
神经病学 | 475篇 |
特种医学 | 548篇 |
外科学 | 559篇 |
综合类 | 90篇 |
一般理论 | 10篇 |
预防医学 | 385篇 |
眼科学 | 95篇 |
药学 | 279篇 |
中国医学 | 1篇 |
肿瘤学 | 319篇 |
出版年
2021年 | 40篇 |
2018年 | 60篇 |
2017年 | 49篇 |
2016年 | 67篇 |
2015年 | 56篇 |
2014年 | 116篇 |
2013年 | 171篇 |
2012年 | 198篇 |
2011年 | 227篇 |
2010年 | 128篇 |
2009年 | 105篇 |
2008年 | 174篇 |
2007年 | 236篇 |
2006年 | 240篇 |
2005年 | 206篇 |
2004年 | 220篇 |
2003年 | 209篇 |
2002年 | 187篇 |
2001年 | 170篇 |
2000年 | 203篇 |
1999年 | 148篇 |
1998年 | 85篇 |
1997年 | 70篇 |
1996年 | 91篇 |
1995年 | 95篇 |
1994年 | 65篇 |
1993年 | 75篇 |
1992年 | 171篇 |
1991年 | 156篇 |
1990年 | 176篇 |
1989年 | 175篇 |
1988年 | 157篇 |
1987年 | 146篇 |
1986年 | 139篇 |
1985年 | 140篇 |
1984年 | 103篇 |
1983年 | 95篇 |
1982年 | 67篇 |
1981年 | 50篇 |
1980年 | 47篇 |
1979年 | 82篇 |
1978年 | 56篇 |
1977年 | 40篇 |
1976年 | 64篇 |
1975年 | 46篇 |
1974年 | 44篇 |
1973年 | 56篇 |
1972年 | 51篇 |
1971年 | 41篇 |
1970年 | 40篇 |
排序方式: 共有6092条查询结果,搜索用时 15 毫秒
101.
Establishing a Fracture Liaison Service (FLS) to identify and treat patients with a recent fragility fracture has been shown to be effective, save money, useful to document high quality of care, and makes good clinical sense. A FLS starts with an osteoporosis champion and encompasses identification of patients with a recent fracture, diagnostic workup, treatment, and follow-up. A FLS is most effective when it is able to function in multiple settings: the hospital, emergency department, and outpatient clinic. Implementation may be somewhat easier in a closed healthcare system but can be feasible even in an open system. There are many barriers to implementation which can be addressed. The future of FLS care lies in a collaborative systems-based approach with appropriate stakeholder engagement, leading to seamless integration of osteoporosis care. 相似文献
102.
Georg Hahn Sharon M. Lutz Julian Hecker Dmitry Prokopenko Michael H. Cho Edwin K. Silverman Scott T. Weiss Christoph Lange 《Genetic epidemiology》2021,45(1):82-98
locStra is an ‐package for the analysis of regional and global population stratification in whole‐genome sequencing (WGS) studies, where regional stratification refers to the substructure defined by the loci in a particular region on the genome. Population substructure can be assessed based on the genetic covariance matrix, the genomic relationship matrix, and the unweighted/weighted genetic Jaccard similarity matrix. Using a sliding window approach, the regional similarity matrices are compared with the global ones, based on user‐defined window sizes and metrics, for example, the correlation between regional and global eigenvectors. An algorithm for the specification of the window size is provided. As the implementation fully exploits sparse matrix algebra and is written in C++, the analysis is highly efficient. Even on single cores, for realistic study sizes (several thousand subjects, several million rare variants per subject), the runtime for the genome‐wide computation of all regional similarity matrices does typically not exceed one hour, enabling an unprecedented investigation of regional stratification across the entire genome. The package is applied to three WGS studies, illustrating the varying patterns of regional substructure across the genome and its beneficial effects on association testing. 相似文献
103.
Yufei Dai Dianzhi Ren Bryan A. Bassig Roel Vermeulen Wei Hu Yong Niu Huawei Duan Meng Ye Tao Meng Jun Xu Ping Bin Meili Shen Jufang Yang Wei Fu Kees Meliefste Debra Silverman Nathaniel Rothman Qing Lan Yuxin Zheng 《Environmental and molecular mutagenesis》2018,59(2):144-150
The International Agency for Research on Cancer has classified diesel engine exhaust (DEE) as a human lung carcinogen. Given that inflammation is suspected to be an important underlying mechanism of lung carcinogenesis, we evaluated the relationship between DEE exposure and the inflammatory response using data from a cross‐sectional molecular epidemiology study of 41 diesel engine testing workers and 46 unexposed controls. Repeated personal exposure measurements of PM2.5 and other DEE constituents were taken for the diesel engine testing workers before blood collection. Serum levels of six inflammatory biomarkers including interleukin (IL)‐1, IL‐6, IL‐8, tumor necrosis factor (TNF)‐α, macrophage inflammatory protein (MIP)‐1β, and monocyte chemotactic protein (MCP)‐1 were analyzed in all subjects. Compared to unexposed controls, concentrations of MIP‐1β were significantly reduced by ~37% in DEE exposed workers (P < 0.001) and showed a strong decreasing trend with increasing PM2.5 concentrations in all subjects (Ptrend < 0.001) as well as in exposed subjects only (Ptrend = 0.001). Levels of IL‐8 and MIP‐1β were significantly lower in workers in the highest exposure tertile of PM2.5 (>397 µg/m3) compared to unexposed controls. Further, significant inverse exposure‐response relationships for IL‐8 and MCP‐1 were also found in relation to increasing PM2.5 levels among the DEE exposed workers. Given that IL‐8, MIP‐1β, and MCP‐1 are chemokines that play important roles in recruitment of immunocompetent cells for immune defense and tumor cell clearance, the observed lower levels of these markers with increasing PM2.5 exposure may provide insight into the mechanism by which DEE promotes lung cancer. Environ. Mol. Mutagen. 59:144–150, 2018. © 2017 Wiley Periodicals, Inc. 相似文献
104.
105.
106.
107.
Kristoffer S. Berlin PhD W. Hobart Davies Alan H. Silverman Douglas W. Woods Elizabeth A. Fischer Colin D. Rudolph 《Children's Health Care》2013,42(2):142-156
A caregiver questionnaire that assesses mealtime problems in children aged 2 to 6 years old was developed. Community caregivers (n = 712) completed the Mealtime Behavior Questionnaire (MBQ) and measures of child behavior and family mealtime behaviors and environment. Exploratory and confirmatory factor analyses revealed and validated the MBQ's 4 subscales (food refusal/avoidance; food manipulation; mealtime aggression/distress; and choking/, gagging/vomiting). Mealtime problems occurred from “sometimes” to “always” for 1% to 61% of the sample. The MBQ demonstrated excellent to fair internal consistencies, and preliminary evidence for validity was found. 相似文献
108.
109.
Stuart Silverman 《Current osteoporosis reports》2013,11(4):354-356
Recognizing the significant impact of osteoporosis, The Joint Commission has worked since 2005 to develop performance measures in osteoporosis across the care continuum. This work has led to the development of 3 measures, which may be used at any time to meet hospital quality improvement goals. Plans are in place to submit to the National Quality Forum for endorsement as national consensus standards. The measures were developed under the guidance of a 12 member Technical Advisory Panel. 相似文献
110.