Prediction of depression with the apperceptive personality test

This study examined the relationship between depression and the Apperceptive Personality Test (APT), a picture-story assessment device with an objective scoring system. Subjects were 206 undergraduate volunteer females who completed the APT and the Beck Depression Inventory (BDI). Multiple regression analysis showed significant APT predictors for the BDI. Results are discussed and directions for future research are proposed.     

Success rates in minimal stimulation cycle IVF with clomiphene citrate only

Journal of Assisted Reproduction and Genetics - To determine age-adjusted overall success rates for patients undergoing clomiphene citrate only minimal stimulation cycle (mini) in vitro...     

Autonomic dysfunction and phenoconversion in idiopathic REM sleep behavior disorder

Clinical Autonomic Research - REM sleep behavior disorder (RBD) is a common finding among patients with synucleinopathies. We aimed to determine the degree of autonomic dysfunction in patients...     

Factor structure of the Apperceptive Personality Test (APT).

This study examined the factor structure of the Apperceptive Personality Test (APT), a recently developed picture-story technique with both projective and objective features. University undergraduates (513 males, 664 females) were administered the APT in individual group sessions. A principal components analysis (Varimax rotation) was performed with 18 of the standard APT variables and resulted in three similar factors for both male and female samples. The first and largest factor was a positive evaluation factor, the second a negative evaluation factor, and the third an "intensity" factor. The usefulness and meaning of the factor analysis are discussed briefly.     

基于薄板样条和形状内容的医学图像非刚性配准方法研究

目的 针对医学图像非刚性点配准的现状,给出一种基于点特征的非刚性配准方法.方法 利用一种新的相似度测量方法--形状内容来解决两幅图像中点的对应关系,并利用点对应关系来估计非刚性映射函数.结果 利用薄板样条实现了医学图像的快速准确非刚性配准.结论 实验结果表明,上述方法获得了很好的配准效果.     

Integration of Merged Delayed‐Enhanced Magnetic Resonance Imaging and Multidetector Computed Tomography for the Guidance of Ventricular Tachycardia Ablation: A Pilot Study

MDCT/MRI Fusion for the Guidance of VT Ablation . Background: Delayed enhancement (DE) MRI can assess the fibrotic substrate of scar‐related VT. MDCT has the advantage of inframillimetric spatial resolution and better 3D reconstructions. We sought to evaluate the feasibility and usefulness of integrating merged MDCT/MRI data in 3D‐mapping systems for structure–function assessment and multimodal guidance of VT mapping and ablation. Methods: Nine patients, including 3 ischemic cardiomyopathy (ICM), 3 nonischemic cardiomyopathy (NICM), 2 myocarditis, and 1 redo procedure for idiopathic VT, underwent MRI and MDCT before VT ablation. Merged MRI/MDCT data were integrated in 3D‐mapping systems and registered to high‐density endocardial and epicardial maps. Low‐voltage areas (<1.5 mV) and local abnormal ventricular activities (LAVA) during sinus rhythm were correlated to DE at MRI, and wall‐thinning (WT) at MDCT. Results: Endocardium and epicardium were mapped with 391 ± 388 and 1098 ± 734 points per map, respectively. Registration of MDCT allowed visualization of coronary arteries during epicardial mapping/ablation. In the idiopathic patient, integration of MRI data identified previously ablated regions. In ICM patients, both DE at MRI and WT at MDCT matched areas of low voltage (overlap 94 ± 6% and 79 ± 5%, respectively). In NICM patients, wall‐thinning areas matched areas of low voltage (overlap 63 ± 21%). In patients with myocarditis, subepicardial DE matched areas of epicardial low voltage (overlap 92 ± 12%). A total number of 266 LAVA sites were found in 7/9 patients. All LAVA sites were associated to structural substrate at imaging (90% inside, 100% within 18 mm). Conclusion: The integration of merged MDCT and DEMRI data is feasible and allows combining substrate assessment with high‐spatial resolution to better define structure–function relationship in scar‐related VT. (J Cardiovasc Electrophysiol, Vol. 24, pp. 419‐426, April 2013)     

多囊卵巢综合征患者复方醋酸环丙孕酮治疗前后激素和糖代谢变化的临床观察

为观察达英-35治疗多囊卵巢综合征(PCOS)在明显降低黄体生成素(LH)及睾酮(T)水平,改善患者内分泌状况的同时,是否改善其胰岛素抵抗(IR),35例PCOS患者服用复方醋酸环丙孕酮(达英-35)治疗3个周期,观察用药前后临床特征、血清激素水平、空腹血糖、空腹胰岛素(FIN)的变化.结果显示,治疗后34例PCOS患者月经恢复,多毛及痤疮评分下降(P<0.01),双侧卵巢体积明显缩小(P<0.01).血清LH、FSH、T水平和LH/FSH明显下降(P<0.01).FIN水平明显下降(P<0.01),IR也有相应降低(P<0.01),空腹血糖(FBG)和胰岛素敏感性指数(ISI)无明显改变(P>0.05).达英-35有很强的抗雄作用,明显改善了PCOS患者的内分泌状况和临床症状.     

类肿瘤型舍格伦综合征诊断问题的初步探讨

目的：探讨类肿瘤型舍格伦综合征的特点和诊断方法。方法对２２例腮腺区类肿瘤型舍格伦综合征、５０例腮腺多形性腺瘤和２５例腮腺淋巴瘤,进行各项临床资料内容的卡方检验及逐步判别分析。结果（１）类肿瘤型舍格伦综合征好于４０－５９岁的女性,局部表现为涎腺区肿块,质中、表面光滑、有酸胀和时大时小现象,还有口干、眼干和关节酸痛等全身症状,抗炎治疗有效。（２）建立了类肿瘤型舍格伦综合征、多形性腺瘤和腺淋巴瘤的判别函     

高效液相色谱串联质谱法测定血清非结合雌三醇的前处理研究

目的优化高效液相色谱串联质谱法(LC-MS/MS)测定血清游离雌三醇(uE3)的前处理方法。方法以活性炭吸附血清为研究基质,通过加入已知量的雌三醇(E3)标准品及E3-2-3-4-13 C3内标,在LC-20AD XR高效液相色谱系统和API 5500串联四级杆质谱仪上对E3检测的色谱条件、质谱条件及萃取条件等进行优化。结果色谱条件:选用菲罗门Knietex色谱柱(100.0mm×2.1mm,2.6μm);有机相为甲醇,水相为0.1mmol/L氟化铵水溶液,8min梯度洗脱。质谱条件:选用电喷雾(ESI)负离子模式和多反应监测(MRM)模式分析,选择质荷比(m/z)287→m/z 145作为E3的定量离子对,m/z 287→m/z 171作为定性监测离子对;选择m/z 290→m/z 148作为内标的定量离子对,m/z 290→m/z 174作为定性监测的离子对。萃取条件:萃取剂为正己烷/乙酸乙酯(50/50,v/v),样品与萃取剂的比例为1∶2,萃取率可达85.71%。结论 E3检测的色谱条件、质谱条件、萃取条件已得到全面优化,为后续建立LC-MS/MS测定人血中uE3的参考方法打下良好基础。     

单倍剂量三维对比增强MRA诊断脑动静脉畸形的临床价值

目的探讨使用单倍剂量三维对比增强MRA对诊断脑动静脉畸形（AVM）的临床价值。材料与方法 11例经手术或DSA证实的脑AVM患者,均先行常规MRI检查,接着进行单倍剂量三维对比增强MRA检查。结果脑AVM SD 3D-CE-MRA表现：有10例患者明确显示异常血管团、供血动脉和引流静脉,其中,单支供血动脉6例,联合供血4例,单支静脉引流7例,多支静脉引流3例。1例3D CE-MRA显示正常。结论联合应用SD 3D CE-MRA和常规MRI检查,对脑AVM的诊断及指导临床治疗有十分重要的价值。