非淋菌性尿道炎合并盆腔感染药物治疗效果对比研究

目的探讨临床上对非淋菌性尿道(宫颈)炎合并盆腔感染有效的治疗方法。方法将妇产科及性病科门诊确诊的非淋菌性尿道(宫颈)炎合并盆腔感染201例病人随机分为2组,治疗组采用头孢曲松纳加阿奇霉素治疗,对照组采用头孢曲松纳加口服美满霉素治疗。结果治疗组治愈率为80.95%,总有效率为97.14%;对照组治愈率为58.33%,总有效率为69.79%。两者的,临床治愈率及有效率有显著性的差异(P<0.005)。结论头孢曲松纳加阿奇霉素静脉给药治疗非淋菌性尿道(宫颈)炎合并盆腔感染取得良好的治疗效果,较头孢曲松纳加美满霉素效果有显著性提高。     

高眼压下小梁切除术23例临床分析

目的 探讨高眼压状态下施行小梁切除术的疗效。方法 术前术中用多种方法使眼压逐渐下降后，再按常规完成手术。结果 82．6％的患者术后不用抗青光眼药物，眼压能控制在21mmHg以下，无严重并发症发生。结论 对青光眼患者眼压不能满意控制的情况下，应该果断选择手术治疗。     

Ocular component measurement using the Zeiss IOLMaster.

PURPOSE: Axial length is traditionally measured using A-scan ultrasound. The IOLMaster is a new instrument that uses partial coherence interferometry to measure axial length. We compared the repeatability of these techniques for both an experienced and an inexperienced observer, the agreement between the two techniques, and the effect of cycloplegia on IOLMaster measurements. METHODS: Five measurements of axial length and three measurements of anterior chamber depth were taken with the IOLMaster in two sessions separated by 1 to 12 days in 20 young adults. The two examiners each took measurements, and the subject was then cyclopleged with 1% tropicamide. The IOLMaster readings were then repeated by both examiners, followed by five ultrasound readings. Repeatability was evaluated by calculating the difference between measurements from the two sessions. The mean and standard deviation of these differences was then used to determine the 95% limits of agreement (LoA) for each technique. In addition, the agreement between the IOLMaster and ultrasound was assessed, along with the effect of cycloplegia on IOLMaster readings. RESULTS: The IOLMaster was more repeatable than ultrasound. For axial length, the 95% LoA were -0.11 to +0.07 mm, -0.06 to +0.05 mm, and -0.25 to +0.35 mm, for noncycloplegic IOLMaster, cycloplegic IOLMaster, and ultrasound, respectively. The two instruments showed modest agreement with each other (mean difference, +0.12 mm; 95% LoA, -0.39 to +0.64 mm; p > 0.0125). Cycloplegia had no significant effect on IOLMaster axial length measurements. The 95% LoA for anterior chamber depth measurement were -0.11 to +0.18 mm, -0.06 to +0.04 mm, and -0.19 to +0.21 mm, for noncycloplegic IOLMaster, cycloplegic IOLMaster, and ultrasound, respectively. The IOLMaster gave significantly longer anterior chamber depths than ultrasound (mean, +0.18 mm; 95% LoA, -0.02 to +0.37 mm; p < 0.0125), and cycloplegia produced significantly deeper anterior chamber depths using the IOLMaster (mean, +0.12 +/- 0.09 mm; 95% LoA, -0.05 to +0.29 mm; t = 6.17; p < 0.001). The experienced observer's measurements were more repeatable than the inexperienced observer's for ultrasound, but not for the IOLMaster. CONCLUSIONS: The superior repeatability of the IOLMaster suggests that it should become the standard for axial length measurement. The 95% limits of agreement for the cycloplegic measurements correspond to a change in refractive error of +/-0.12 D.     

细辛脑注射液对支气管哮喘患儿呼吸道炎症因子的影响

目的观察细辛脑对支气管哮喘患儿呼吸道炎症因子的影响。方法共选取60例支气管哮喘患儿,随机分成2组,治疗组予细辛脑注射液0.5 mg/kg,用10%葡萄糖注射液稀释成0.01%的溶液,静脉滴注,2次/d;对照组用氨茶碱针4~6 mg/kg加入5%葡萄糖注射液100 mL静脉滴注,1次/d,两组均用7 d为1个疗程,共观察2个疗程。结果治疗2周后,两组嗜酸性粒细胞与巨噬细胞治疗前后比较均有明显差异(P均<0.05),同时治疗组的淋巴细胞、CD4 T细胞与治疗前比较均有明显差异(P均<0.05),两组嗜酸性粒细胞、巨噬细胞、淋巴细胞、CD4 T细胞比较也均有明显差异(P均<0.05)。治疗后两组肺功能均比治疗前明显改善(P均<0.05),治疗组的肺功能I、L-5与对照组有明显差异(P<0.05)。结论细辛脑注射液对哮喘患儿呼吸道炎症因子的影响优于氨茶碱组。     

ELEKTA Precise 医用直线加速器波导隔离器维修

本文介绍了波导隔离器在加速器微波系统中的作用、特点,以及Precise加速器上波导隔离器散热水套渗水的处理方法.     

中医药戒毒的回顾和展望

毒品泛滥仍然是当今严重的社会问题之一.中医中药戒毒已有百年历史,因其安全、有效、价廉、副作用小的特点,近几年先后批准9个处方上市,受到广泛关注.中医药戒毒注重整体调节和辨证论治,对毒品成瘾的病因、病机和治疗原则等都有其独到的认识.现将国内外有关中医药戒毒的研究现状作一简单回顾和展望.     

The novel infra‐pectineal buttress plates used for internal fixation of elderly quadrilateral surface involved acetabular fractures

ObjectivesIn geriatric acetabular fractures, the quadrilateral surface (QLS) was frequently involved in acetabular fracture patterns and accompanied by medial displacement. It was important to buttress the medial displaced QLS and reconstruct the congruity of the affected acetabulum. To evaluate the clinical effectiveness of the novel infra‐pectineal quadrilateral surface buttress plates for the treatment of geriatric acetabular fractures.MethodsTwenty‐three geriatric patients who were treated for acetabular fractures involving QLS with the novel infra‐pectineal buttress plates (NIBP) through a single supra‐ilioinguinal approach between January 2015 and June 2019 were retrospectively analyzed; all patients received at least 1 year''s follow‐up. All patients were aged ≥60 years old and including 18 males and five females. Radiologic and clinical outcomes of patients involved in the study were collated and analyzed according to the Matta scoring system and the Merle D''Aubigné–Postel scoring system. The functional recovery scoring was compared using q‐test.ResultsAll 23 consecutive patients had relatively satisfactory clinical treatment effectiveness. Average ages, length of incision, operation time, and intraoperative blood loss were 69.8 ± 6.1 years, 12.1 ± 2.6 cm, 166.5 ± 43.5 min, and 500 (500,700) ml, respectively. According to the Matta scoring system, 14 cases of reduction were graded as excellent, five as good, and four as fair. At the last follow‐up, the clinical outcome evaluation was excellent in 13 cases, good in seven cases, and poor in three cases with the use of the Merle D''Aubigné–Postel scoring system. The difference of modified Merle D''Aubigne‐Postel score at 3 months, 6 months and last follow up was statistically significant (F = 21.56, p < 0.05). Postoperative lateral femoral cutaneous nerve injury occurred in three patients and heterotopic ossification occurred in one patient.ConclusionsFor the treatment of geriatric acetabular fractures, the NIBP could provide stable and effective fixation to the QLS involved acetabular fractures, and related satisfactory clinical results with few complications were noted.     

三种螺距对种植体初期稳定性影响的有限元研究

目的：利用即刻负载有限元模型,研究种植体不同螺纹螺距因素对初期稳定性的影响。方法：利用Pro／E软件、Hypermesh软件及ABAQUS有限元软件,建立四类种植体即刻负载的三维有限元模型,比较3种螺纹螺距（0．8mm、1．6mm、2．4mm）在分别垂直和水平加载时,对种植体初期稳定性的影响。结果：对不同螺纹螺距种植体来说,垂直加载和水平加载时0．8mm螺距螺纹种植体微动最小,2．4mm螺距螺纹种植体微动最大。结论：螺纹的螺距对垂直相对位移有影响,对水平相对位移影响不大。随着螺距的增加,种植体对抗垂直向载荷的抵抗力减弱。水平加载时,螺纹的螺距对颈部微动影响不明显。     

The Biomarkers for Predicting Viral Hepatitis-Associated Hepatocellular Carcinoma

BackgroundHepatocellular carcinoma (HCC) is the fifth most common cancer in the world, and more than half of the newly diagnosed cases are chronic hepatitis B patients. Due to the lack of specific clinical manifestations, many patients are already at an advanced stage at the time of diagnosis and therefore have missed the best time for treatment. Organs in a pathological state usually secrete specific substances into the blood, which can indirectly indicate the pathological state of the organ, so some biological markers in the blood can be used as a tool to predict the incidence of HCC.MethodsThe Research articles related to HCC were collected by searching PubMed databases with the keywords “hepatocellular carcinoma”, “serum biomarker”, “hepatitis B”, “prediction” and “prognosis”, and Additional articles were identified by manual search of references found in the primary articles, followed by a summary and review.ResultsViral hepatitis is the main cause of HCC worldwide, and this phenomenon is particularly prominent in Asian and African populations. A variety of serological markers including M2BPGi, IL-6 and COMP can be used to predict the incidence of long-term HCC in patients. The risk of HCC is dynamic rather than constant, and dynamic detection will help improve prediction accuracy. For hepatitis B patients, HBV DNA load and HBcr Ag are important predictive markers of HCC.ConclusionFor a high-risk population of HCC, early risk prediction is helpful to guide clinical work, and timely adjustments of the screening frequency and treatment plan are helpful to prolong the survival time of HCC patients.