全文获取类型
收费全文 | 34549篇 |
免费 | 2240篇 |
国内免费 | 210篇 |
专业分类
耳鼻咽喉 | 298篇 |
儿科学 | 684篇 |
妇产科学 | 553篇 |
基础医学 | 4550篇 |
口腔科学 | 1015篇 |
临床医学 | 3479篇 |
内科学 | 7554篇 |
皮肤病学 | 775篇 |
神经病学 | 3721篇 |
特种医学 | 2385篇 |
外国民族医学 | 1篇 |
外科学 | 5465篇 |
综合类 | 192篇 |
一般理论 | 18篇 |
预防医学 | 1318篇 |
眼科学 | 748篇 |
药学 | 1946篇 |
中国医学 | 35篇 |
肿瘤学 | 2262篇 |
出版年
2023年 | 318篇 |
2022年 | 668篇 |
2021年 | 1151篇 |
2020年 | 660篇 |
2019年 | 884篇 |
2018年 | 1062篇 |
2017年 | 882篇 |
2016年 | 1065篇 |
2015年 | 1208篇 |
2014年 | 1473篇 |
2013年 | 1718篇 |
2012年 | 2632篇 |
2011年 | 2580篇 |
2010年 | 1569篇 |
2009年 | 1496篇 |
2008年 | 2175篇 |
2007年 | 2254篇 |
2006年 | 1923篇 |
2005年 | 1869篇 |
2004年 | 1715篇 |
2003年 | 1591篇 |
2002年 | 1397篇 |
2001年 | 403篇 |
2000年 | 381篇 |
1999年 | 403篇 |
1998年 | 298篇 |
1997年 | 244篇 |
1996年 | 185篇 |
1995年 | 150篇 |
1994年 | 140篇 |
1993年 | 132篇 |
1992年 | 175篇 |
1991年 | 166篇 |
1990年 | 143篇 |
1989年 | 176篇 |
1988年 | 116篇 |
1987年 | 103篇 |
1986年 | 113篇 |
1985年 | 91篇 |
1984年 | 76篇 |
1983年 | 65篇 |
1982年 | 62篇 |
1980年 | 54篇 |
1979年 | 93篇 |
1978年 | 63篇 |
1977年 | 57篇 |
1974年 | 65篇 |
1973年 | 56篇 |
1972年 | 58篇 |
1971年 | 62篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Interprofessional collaboration and communication in nursing homes: a qualitative exploration of problems in medical care for nursing home residents – study protocol 下载免费PDF全文
2.
Methicillin‐resistant Staphylococcus aureus eradication in young infants should include the diaper area and treat housing contacts 下载免费PDF全文
3.
4.
Sarah Hallas Andrea Nelson Susan O'Meara Una Adderley Pauline Meskell Jane Nixon Aonghus O'Loughlin Sebastian Probst Wael Tawfick Thomas Wild Georgina Gethin 《Journal of tissue viability》2021,30(3):317-323
BackgroundA venous leg ulcer is a chronic leg wound caused by poor venous blood circulation in the lower limbs. It is a recurring condition causing pain, malodour, reduced mobility, and depression. Randomised controlled trials evaluating treatments for venous leg ulcers provide important evidence to inform clinical decision-making. However, for findings to be useful, outcomes need to be clinically meaningful, consistently reported across trials, and fully reported. Research has identified the large number of outcomes reported in venous leg ulcer trials, impacting both synthesis of results, and clinical decision-making. To address this, a core outcome set will be developed. A core outcome set is an agreed standardised set of outcomes which should be, as a minimum, measured and reported in all trials which evaluate treatment effectiveness for a given indication. A core outcome set has the potential to reduce research waste, improve the utility of RCTs, reduce reporting bias, facilitate treatment comparisons across different sources of evidence and expedite the production of systematic reviews, meta-analyses and evidence-based clinical guidelines.AimThe aim of this project is to develop a core outcome set for research evaluating the effectiveness of interventions for treating venous leg ulceration.MethodsThrough a scoping review of the literature on venous leg ulceration, we will firstly identify a list of candidate outcome domains (broad categories in relation to what is being measured) from randomised controlled trials and qualitative research, and outcomes (specific methods in relation to what is being measured). In two further stages, we will use the resulting lists of outcome domains and outcomes to design two online surveys. A range of stakeholders will be invited to participate in the surveys and they will be asked to indicate which outcome domains and outcomes are most important and should be considered as core in future research reports. 相似文献
5.
6.
Raphael Mohr Robert Schierwagen Carolynne Schwarze-Zander Christoph Boesecke Jan-Christian Wasmuth Jonel Trebicka Jürgen Kurt Rockstroh 《Medicine》2015,94(50)
Liver-related death in human immunodeficiency virus (HIV)-infected individuals is about 10 times higher compared with the general population, and the prevalence of significant liver fibrosis in those with HIV approaches 15%. The present study aimed to assess risk factors for development of hepatic fibrosis in HIV patients receiving a modern combination anti-retroviral therapy (cART).This cross-sectional prospective study included 432 HIV patients, of which 68 (16%) patients were anti-hepatitis C virus (HCV) positive and 23 (5%) were HBsAg positive.Health trajectory including clinical characteristics and liver fibrosis stage assessed by transient elastography were collected at inclusion. Liver stiffness values >7.1 kPa were considered as significant fibrosis, while values >12.5 kPa were defined as severe fibrosis. Logistic regression and Cox regression uni- and multivariate analyses were performed to identify independent factors associated with liver fibrosis.Significant liver fibrosis was detected in 10% of HIV mono-infected, in 37% of HCV co-infected patients, and in 18% of hepatitis B virus co-infected patients. The presence of diabetes mellitus (odds ratio [OR] = 4.6) and FIB4 score (OR = 2.4) were independently associated with presence of significant fibrosis in the whole cohort. Similarly, diabetes mellitus (OR = 5.4), adiposity (OR = 4.6), and the FIB4 score (OR = 3.3) were independently associated with significant fibrosis in HIV mono-infected patients. Importantly, cumulative cART duration protected, whereas persistent HIV viral replication promoted the development of significant liver fibrosis along the duration of HIV infection.Our findings strongly indicate that besides known risk factors like metabolic disorders, HIV may also have a direct effect on fibrogenesis. Successful cART leading to complete suppression of HIV replication might protect from development of liver fibrosis. 相似文献
7.
8.
Sebastian Bonner Thomas Matte Mitchell Rubin Joanne K Fagan Jennifer Ahern David Evans 《The Journal of asthma》2006,43(1):31-35
Although studies have documented underuse of controller medications and overuse of short-acting inhaled ss(2)-agonist among children with persistent asthma in disadvantaged communities, the persistence of oral ss(2)-agonist use in pediatric practice has not been studied since inhaled short-acting ss(2)-agonists became widespread. We describe medications used to treat asthma among children 3 to 5 years of age at 10 Head Start and other subsidized preschool centers in East and Central Harlem, New York City. We interviewed 149 parents/guardians of children who were identified as having probable asthma based on physician's diagnosis, persistent symptoms, hospitalization, and medication use. We classified 86 of the 149 children (58%) as having current persistent asthma. Only 15 of them (17%) were reported to have used controller medications at least 5 days/week in the last 4 weeks-only 2 of whom used inhaled corticosteroids. By contrast, 53 children (62%) used oral ss(2)-agonist in the last 4 weeks, often (72%) in conjunction with nebulized or inhaled short-acting ss(2)-agonist. Use of oral ss(2)-agonist was associated with more severe symptoms. This study documents the continued widespread use of oral ss(2)-agonist for treatment of children in a low-income community with high prevalence of asthma. 相似文献
9.
Christoph Mulert Georg Juckel Michael Brunnmeier Susanne Karch Gregor Leicht Roland Mergl Hans-Jürgen M?ller Ulrich Hegerl Oliver Pogarell 《Clinical EEG and neuroscience》2007,38(2):78-81
During the last 10 years the knowledge about rostral anterior cingulate cortex (ACC) activity in major depression has substantially increased. Several groups have independently described a relationship between resting activity in this area and response to antidepressant treatment. We have recently confirmed a relationship between resting activity of rostral ACC activity and response in a group of 20 patients with major depression using resting theta activity. In this earlier study regions of interest (ROI) were defined in order to establish regional specificity. Differences between responders and nonresponders were only found in the ACC-ROI, but not in the posterior cingulate region. We have now reanalyzed our data using a whole brain voxelwise approach, in order not to miss any other relevant functional differences. In addition to major differences between responders and nonresponders in the rostral ACC, we have identified a nearby region in the midline orbito-frontal region. 相似文献
10.
Trauma und Berufskrankheit - Zusammenfassung Die angemessene Behandlung der Radiusköpfchenfrakturen erfolgt nach korrekter Klassifikation unter Berücksichtigung von Begleitverletzungen... 相似文献