全文获取类型
收费全文 | 536篇 |
免费 | 29篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 19篇 |
儿科学 | 36篇 |
妇产科学 | 36篇 |
基础医学 | 50篇 |
口腔科学 | 51篇 |
临床医学 | 50篇 |
内科学 | 100篇 |
皮肤病学 | 10篇 |
神经病学 | 29篇 |
特种医学 | 24篇 |
外科学 | 76篇 |
综合类 | 13篇 |
预防医学 | 18篇 |
眼科学 | 14篇 |
药学 | 33篇 |
肿瘤学 | 13篇 |
出版年
2024年 | 1篇 |
2023年 | 13篇 |
2022年 | 15篇 |
2021年 | 20篇 |
2020年 | 14篇 |
2019年 | 14篇 |
2018年 | 18篇 |
2017年 | 5篇 |
2016年 | 23篇 |
2015年 | 32篇 |
2014年 | 30篇 |
2013年 | 39篇 |
2012年 | 46篇 |
2011年 | 36篇 |
2010年 | 18篇 |
2009年 | 11篇 |
2008年 | 31篇 |
2007年 | 36篇 |
2006年 | 43篇 |
2005年 | 42篇 |
2004年 | 28篇 |
2003年 | 20篇 |
2002年 | 20篇 |
2001年 | 2篇 |
1999年 | 1篇 |
1998年 | 4篇 |
1996年 | 3篇 |
1995年 | 2篇 |
1993年 | 2篇 |
1992年 | 2篇 |
1961年 | 1篇 |
排序方式: 共有572条查询结果,搜索用时 15 毫秒
51.
Although concern for patient safety is inherent to the practice of the health care professions, its transformation into a specific body of knowledge is relatively recent and thus patient safety may be considered as a comparatively ‘new’ discipline. Its main objectives are to avoid the occurrence of preventable adverse events (accidents, errors and complications) associated with health care and to limit the impact of inevitable adverse events. Despite these simple definitions, patient safety is multifaceted, quite complex in nature and includes many key elements. Thus, it cannot be simply defined as the provision of safe health care or the protection of patients from harm by health care providers because there are economic, fiscal, social, cultural and organisational aspects of a patient safety climate. It is essential for all health care practitioners and health care organisations to become more familiar with the general context of patient safety, to actively participate in efforts to implement patient safety measures in daily practice and to establish a patient safety culture. 相似文献
52.
Nermin Yönel Floris J. Bikker Maxim D. Lagerweij Cees J. Kleverlaan Cor van Loveren Bugra Özen Serap Çetiner Augustinus J. P. van Strijp 《European journal of oral sciences》2016,124(4):396-402
A selection of commercially available products containing stannous fluoride (SnF2)/sodium fluoride (NaF), SnF2/amorphous calcium phosphate (ACP), SnF2/NaF/ACP, tin (Sn)/fluorine (F)/chitosan were compared with phytosphingosine (PHS) with respect to their anti‐erosive properties in vitro. One‐hundred and twenty bovine enamel specimens were immersed in the respective product slurries for 2 min, twice daily. The formulations were diluted with either remineralization solution or artificial saliva. After each treatment, an erosive challenge was performed for 10 min, twice daily, using citric acid, pH 3.4. The specimens were stored in remineralization solution or artificial saliva until the next treatment‐erosion challenge. After 10 d, tissue loss was determined using profilometry. Enamel softening was determined through surface microhardness measurements. Tissue‐loss values (measured in μm and expressed as mean ± SD) for PHS, SnF2/NaF, SnF2/ACP, SnF2/ACP/NaF, and Sn/F/chitosan treatment groups and for the negative‐control group, were, respectively, 35.6 ± 2.8, 15.8 ± 1.8, 22.1 ± 2.0, 22.9 ± 1.8, 16.2 ± 1.2, and 51.2 ± 4.4 in the presence of remineralization solution and 31.7 ± 3.3, 15.6 ± 2.9, 16.5 ± 2.7, 16.8 ± 2.1, 13.1 ± 3.0, and 50.7 ± 2.8 in the presence of artificial saliva. There were no significant differences in surface microhardness measurements between the treatment groups. In conclusion, PHS resulted in a significant reduction of tissue loss compared with the negative control, but in comparison, the toothpastes containing Sn2+ and F? ions were significantly more effective compared with PHS. 相似文献
53.
54.
55.
56.
Primary nephrotic syndrome during childhood in Turkey 总被引:3,自引:0,他引:3
Nuray Özkaya Nilgün Çakar Mesiha Ekim Nazli Kara Nermin Akkök Fatos Yalçinkaya 《Pediatrics international》2004,46(4):436-438
BACKGROUND: Minimal change nephrotic syndrome (MCNS) is the most common cause of primary nephrotic syndrome (NS) during childhood. However, recent studies from different countries have reported an increasing incidence of focal segmental glomerulosclerosis (FSGS) in children. METHODS: This is a retrospective study in which 392 Turkish children who were diagnosed with NS during the last 10 years and were followed for at least 2 years, were evaluated. Mean age of the study group was 4.6 +/- 3.4 years (range 0.9-16 years) and 232 were male and 160 were female. RESULTS: In total, 280 patients were diagnosed as MCNS with their initial presentations, laboratory features, and clinical course. Kidney biopsy was performed in the remaining 112 children according to current recommendations. The results showed that membranoproliferative glomerulonephritis (MPGN) was the most common histopathologic diagnosis, 38 (34%) of the 112 patients were found to have MPGN. The number diagnosed as FSGS was 26 (23%). A significant difference was found between the age groups for both MPGN and FSGS, the former being more common in children >6 years of age and the latter more frequent in children =6 years. MCNS was found in only 19% of all biopsies performed and the total incidence of MCNS (presumptive + biopsy proven) was 76%. There was no significant difference between the incidence of different histopathological subtypes before and after 1995. CONCLUSION: Minimal change nephrotic syndrome is still the most common primary NS in childhood and MPGN is found to be the most common histopathologic subtype in the present patient population who underwent biopsy. 相似文献
57.
58.
59.
Karli N Akiş N Zarifoğlu M Akgöz S Irgil E Ayvacioğlu U Calişir N Haran N Akdoğan O 《Headache》2006,46(4):649-655
BACKGROUND AND OBJECTIVES: The objective of this study was to investigate the prevalence and sociodemographic characteristics of headaches among Turkish adolescents aged 12 to 17 years old in Bursa province of Turkey. METHODS: A multistep, stratified, cluster sampling method was used for subject selection. The estimated sample size for 12- to 14-year-old students was 1,270 and for 15- to 17-year-old students was 1,117. Our study sample included 6.5% of the secondary schools and 1.8% of the students aged 12 to 17 years old. The study was conducted in two phases; the questionnaire phase and the face-to-face interview phase. RESULTS: The prevalence of recurrent headache in the study population was 52.2%. Girls (59.8%) had significantly more recurrent headache than boys (45.1%) The prevalence of recurrent headache increased from 42.2% up to 60.7% by age. In multivariate logistic regression analysis age and gender differed significantly between adolescents with and without recurrent headache groups. Frequent episodic tension-type headache was the most common (25.9%) headache among Turkish adolescents, followed by migraine (14.5%). CONCLUSIONS: Age and gender appeared to be demographic factors increasing adolescent headache prevalence. Frequent episodic-tension type headache was the most common headache followed by migraine. Our migraine prevalence was slightly higher than most of the previously reported prevalence rates. This might be due to the new classification criteria of headache released by International Headache Society. 相似文献
60.
Mohammed Al-Beltagi Nermin Kamal Saeed 《World journal of gastrointestinal pathophysiology》2022,13(5):143-156
The brain and the gut are linked together with a complex, bi-path link known as the gut-brain axis through the central and enteric nervous systems. So, the brain directly affects and controls the gut through various neurocrine and endocrine processes, and the gut impacts the brain via different mechanisms. Epilepsy is a central nervous system (CNS) disorder with abnormal brain activity, causing repeated seizures due to a transient excessive or synchronous alteration in the brain’s electrical activity. Due to the strong relationship between the enteric and the CNS, gastrointestinal dysfunction may increase the risk of epilepsy. Mean while, about 2.5% of patients with epilepsy were misdiagnosed as having gastr ointestinal disorders, especially in children below the age of one year. Gut dysb iosis also has a significant role in epileptogenesis. Epilepsy, in turn, affects the gastrointestinal tract in different forms, such as abdominal aura, epilepsy with abdominal pain, and the adverse effects of medications on the gut and the gut microbiota. Epilepsy with abdominal pain, a type of temporal lobe epilepsy, is an uncommon cause of abdominal pain. Epilepsy also can present with postictal states with gastrointestinal manifestations such as postictal hypersalivation, hyperphagia, or compulsive water drinking. At the same time, antiseizure medic ations have many gastrointestinal side effects. On the other hand, some antis eizure medications may improve some gastrointestinal diseases. Many gut manipulations were used successfully to manage epilepsy. Prebiotics, probiotics, synbiotics, postbiotics, a ketogenic diet, fecal microbiota transplantation, and vagus nerve stimulation were used successfully to treat some patients with epilepsy. Other manipulations, such as omental transposition, still need more studies. This narrative review will discuss the different ways the gut and epilepsy affect each other. 相似文献