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N. B. A. Wahid M. T. Latif L. S. Suan D. Dominick M. Sahani S. A. Jaafar N. Mohd Tahir 《Bulletin of environmental contamination and toxicology》2014,92(3):317-322
This study aims to determine the composition and sources of particulate matter with an aerodynamic diameter of 10 μm or less (PM10) in a semi-urban area. PM10 samples were collected using a high volume sampler. Heavy metals (Fe, Zn, Pb, Mn, Cu, Cd and Ni) and cations (Na+, K+, Ca2+ and Mg2+) were detected using inductively coupled plasma mass spectrometry, while anions (SO4 2?, NO3 ?, Cl? and F?) were analysed using Ion Chromatography. Principle component analysis and multiple linear regressions were used to identify the source apportionment of PM10. Results showed the average concentration of PM10 was 29.5 ± 5.1 μg/m3. The heavy metals found were dominated by Fe, followed by Zn, Pb, Cu, Mn, Cd and Ni. Na+ was the dominant cation, followed by Ca2+, K+ and Mg2+, whereas SO4 2? was the dominant anion, followed by NO3 ?, Cl? and F?. The main sources of PM10 were the Earth’s crust/road dust, followed by vehicle emissions, industrial emissions/road activity, and construction/biomass burning. 相似文献
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Daniella F. Pinho Naveen M. Kulkarni Arun Krishnaraj Sanjeeva P. Kalva Dushyant V. Sahani 《European radiology》2013,23(2):351-359
Objectives
To assess image quality of virtual monochromatic spectral (VMS) images, compared to single-energy (SE) CT, and to evaluate the feasibility of material density imaging in abdominal aortic disease.Methods
In this retrospective study, single-source (ss) dual-energy (DE) CT of the aorto-iliac system in 35 patients (32 male, mean age 76.5 years) was compared to SE-CT. By post-processing the data from ssDECT, VMS images at different energies and material density water (WD) images were generated. The image quality parameters were rated on 5-point scales. The aorto-iliac attenuation and contrast-to-noise ratio (CNR) were recorded. Quality of WD images was compared to true unenhanced (TNE) images. Radiation dose was recorded and statistical analysis was performed.Results
Image quality and noise were better at 70 keV (P?<?0.01). Renal artery branch visualisation was better at 50 keV (P?<?0.005). Attenuation and CNR were higher at 50 and 70 keV (P?<?0.0001). The WD images had diagnostic quality but higher noise than TNE images (P?<?0.0001). Radiation dose was lower using single-phase ssDECT compared to dual-phase SE-CT (P?<?0.0001).Conclusion
70-keV images from ssDECT provide higher contrast enhancement and improved image quality for aorto-iliac CT when compared to SE-CT at 120 kVp. WD images are an effective substitute for TNE images with a potential for dose reduction.Key Points
? Multi-detector computed tomography (MDCT) angiography is now a routine procedure. ? Single-source dual-energy CT (ssDECT) can provide simultaneous data with different kilovoltages. ? 70 keV images showed better image quality than conventional single-energy (SE) CT. ? 70 keV images exhibited less image noise in comparison to SE-CT. 相似文献67.
Sixty-five leprosy patients residing in rural Digapahandi block of Ganjam district were studied during July-August 2001 in order to ascertain their perspectives regarding different MDT services after NLEP functions were integrated into primary health care (PHC) in Orissa after September 1999. They included 43.08% multibacillary (MB) cases and 61.92% paucibacillary (PB) cases. Assessment was done by personal interviews of adult patients and the parents of child cases after verification of their treatment cards at the sub-centre. Patient's knowledge regarding the availability of MDT services under PHC services and utilization of these services were highlighted. Influence of different socio-demographic factors was also studied. Basing on the study results, recommendations were made for sustained NLEP functions through PHC in order to improve the utilization of MDT services, which will help in the elimination of leprosy. 相似文献
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Jason E. Faris Lawrence S. Blaszkowsky Shaunagh McDermott Alexander R. Guimaraes Jackie Szymonifka Mai Anh Huynh Cristina R. Ferrone Jennifer A. Wargo Jill N. Allen Lauren E. Dias Eunice L. Kwak Keith D. Lillemoe Sarah P. Thayer Janet E. Murphy Andrew X. Zhu Dushyant V. Sahani Jennifer Y. Wo Jeffrey W. Clark Carlos Fernandez‐del Castillo David P. Ryan Theodore S. Hong 《The oncologist》2013,18(5):543-548
The objective of our retrospective institutional experience is to report the overall response rate, R0 resection rate, progression‐free survival, and safety/toxicity of neoadjuvant FOLFIRINOX (5‐fluorouracil [5‐FU], oxaliplatin, irinotecan, and leucovorin) and chemoradiation in patients with locally advanced pancreatic cancer (LAPC). Patients with LAPC treated with FOLFIRINOX were identified via the Massachusetts General Hospital Cancer Center pharmacy database. Demographic information, clinical characteristics, and safety/tolerability data were compiled. Formal radiographic review was performed to determine overall response rates (ORRs). Twenty‐two patients with LAPC began treatment with FOLFIRINOX between July 2010 and February 2012. The ORR was 27.3%, and the median progression‐free survival was 11.7 months. Five of 22 patients were able to undergo R0 resections following neoadjuvant FOLFIRINOX and chemoradiation. Three of the five patients have experienced distant recurrence within 5 months. Thirty‐two percent of patients required at least one emergency department visit or hospitalization while being treated with FOLFIRINOX. FOLFIRINOX possesses substantial activity in patients with LAPC. The use of FOLFIRINOX was associated with conversion to resectability in >20% of patients. However, the recurrences following R0 resection in three of five patients and the toxicities observed with the use of this regimen raise important questions about how to best treat patients with LAPC. 相似文献
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Andrew X Zhu Jeffrey A Meyerhardt Lawrence S Blaszkowsky Avinash R Kambadakone Alona Muzikansky Hui Zheng Jeffrey W Clark Thomas A Abrams Jennifer A Chan Peter C Enzinger Pankaj Bhargava Eunice L Kwak Jill N Allen Sanjay R Jain Keith Stuart Kerry Horgan Susan Sheehan Charles S Fuchs David P Ryan Dushyant V Sahani 《The lancet oncology》2010,11(1):48-54
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