全文获取类型
收费全文 | 4526篇 |
免费 | 309篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 28篇 |
儿科学 | 222篇 |
妇产科学 | 184篇 |
基础医学 | 617篇 |
口腔科学 | 83篇 |
临床医学 | 780篇 |
内科学 | 735篇 |
皮肤病学 | 122篇 |
神经病学 | 358篇 |
特种医学 | 54篇 |
外科学 | 424篇 |
综合类 | 59篇 |
一般理论 | 2篇 |
预防医学 | 640篇 |
眼科学 | 35篇 |
药学 | 191篇 |
中国医学 | 1篇 |
肿瘤学 | 306篇 |
出版年
2023年 | 21篇 |
2022年 | 32篇 |
2021年 | 83篇 |
2020年 | 51篇 |
2019年 | 84篇 |
2018年 | 94篇 |
2017年 | 71篇 |
2016年 | 103篇 |
2015年 | 108篇 |
2014年 | 155篇 |
2013年 | 222篇 |
2012年 | 292篇 |
2011年 | 328篇 |
2010年 | 170篇 |
2009年 | 144篇 |
2008年 | 266篇 |
2007年 | 307篇 |
2006年 | 318篇 |
2005年 | 270篇 |
2004年 | 307篇 |
2003年 | 253篇 |
2002年 | 273篇 |
2001年 | 34篇 |
2000年 | 23篇 |
1999年 | 42篇 |
1998年 | 57篇 |
1997年 | 45篇 |
1996年 | 56篇 |
1995年 | 46篇 |
1994年 | 43篇 |
1993年 | 36篇 |
1992年 | 28篇 |
1991年 | 29篇 |
1990年 | 31篇 |
1989年 | 21篇 |
1988年 | 27篇 |
1987年 | 12篇 |
1986年 | 22篇 |
1985年 | 20篇 |
1984年 | 39篇 |
1983年 | 18篇 |
1982年 | 26篇 |
1981年 | 24篇 |
1980年 | 21篇 |
1979年 | 17篇 |
1978年 | 20篇 |
1977年 | 18篇 |
1976年 | 13篇 |
1974年 | 17篇 |
1968年 | 9篇 |
排序方式: 共有4841条查询结果,搜索用时 15 毫秒
151.
Mark A Brown Susan M Crail Rosemary Masterson Celine Foote Jennifer Robins Ivor Katz Elizabeth Josland Frank Brennan Elizabeth J Stallworthy Brian Siva Cathy Miller A Katalin Urban Cherian Sajiv R Naida Glavish Steven May Robyn Langham Robert Walker Robert G Fassett Rachael L Morton Cameron Stewart Lisa Phipps Helen Healy Ilse Berquier 《Nephrology (Carlton, Vic.)》2013,18(6):401-454
152.
Pamela Grunwell Kirsten Brondsted Gunilla Henningsson Kien Jansonius Jonas Karling Mieke Meijer Ulla Ording Rosemary Wyatt Ellen Vermeij-Zieverink Debbie Sell 《Journal of plastic surgery and hand surgery》2013,47(3):219-229
During the period 1964–73, 286 patients were treated for mandibular fractures. 229 patients (80%) attended the follow-up examination. The length of observation was from 1 to 9 years. The treatment and the follow-up evaluations in the 229 patients are described. Early fracture treatment has been the objective, also in patients who have undergone severe cerebral traumas. Antibiotic prophylaxis was implemented in cases of compound fractures. Preservation of teeth and tooth buds in the line of fracture was attempted. Clinical infection occurred in 0.4% of the patients. At the follow-up examination 1 patient presented with a fracture displacement outside the condylar process. Neither malocclusion nor pseudarthrosis following fracture or after treatment were seen. Permanent sensory disturbances in the innervation area of the mental nerve following fracture occurred in 8%. Radiological examination of the teeth in the line of fracture revealed unnoticed apical bone lesions in 17% of 118 patients. In a further 23% there was a negative response to the vitality test. Follow-up control of mandibular fractures is advised at 12 to 18 months after treatment. 相似文献
153.
Inhibitory control allows individuals to suppress prepotent responses and resist irrelevant stimuli, and is thought to be a core deficit in Attention-deficit/hyperactivity disorder (ADHD). Whereas numerous studies have investigated neural mechanisms underlying inhibitory control deficits in children with ADHD, less is known about underlying mechanisms in young adults with ADHD. This study explores the neural correlates of inhibitory control in college students with ADHD—a population that, despite comparatively high educational attainment, still shows marked functional impairments in academic, social, and occupational functioning. Participants were 54 college students with ADHD and 29 typically developing peers. Specifically the fronto-centrally located N2 and the centro-parietal P3 event-related potential (ERP) components were hypothesized to show decreased amplitudes for the ADHD group due to their known association with inhibitory control. Dense array electroencephalography (EEG) data was collected during a Go/nogo task. Results show lower accuracy rates for the ADHD group and significant reductions in P3 amplitude as well as a trend for reduced N2 amplitude in nogo trials where subjects successfully inhibited a response. Notably, nogo N2 and P3 amplitudes correlated with the number of ADHD symptoms: namely, smaller amplitudes were associated with more symptoms. We conclude that when compared to their typically developing peers, relatively high functioning adults with ADHD still show a deviant neural signature. These results contribute to the growing literature of adult ADHD and increase our understanding of the neural correlates of inhibitory control associated with ADHD. 相似文献
154.
Gina Geffen Rosemary Isles Megan Preece Laurie Geffen 《Neuropsychological rehabilitation》2013,23(1):89-108
JL, a 25-year-old physiotherapist, became densely amnesic following herpes simplex viral encephalitis (HSVE), causing bilateral damage to medial and ventral areas of her frontal and temporal lobes and their associated circuitry. Three years post-onset, her WAIS-R full scale IQ (Verbal 74, Performance 102) showed an estimated loss of ± 50 points. She displayed severe global amnesia and markedly impaired social cognition. However, her immediate memory, perceptual priming, and cognitive problem-solving abilities were relatively spared. Her retention of professional skills was assessed using simulated physiotherapy scenarios. JL was able to demonstrate some procedural skills spontaneously, but was unable to apply them precisely and flexibly to individual patient needs. She showed no memory of theoretical or propositional physiotherapy knowledge, and could neither plan treatment nor reason clinically. Her performance was well below that of four other physiotherapists who had also not practised for 4 years. Thus, despite the relative sparing of her implicit memory, JL's performance lacked the co-ordinated operation of declarative and implicit long-term memory and the links to working memory that are necessary for the flexible performance of complex professional procedures. 相似文献
155.
Kate Fox Hamish Meffin Owen Burns Carla J. Abbott Penelope J. Allen Nicholas L. Opie Ceara McGowan Jonathan Yeoh Arman Ahnood Chi D. Luu Rosemary Cicione Alexia L. Saunders Michelle McPhedran Lisa Cardamone Joel Villalobos David J. Garrett David A. X. Nayagam Nicholas V. Apollo Kumaravelu Ganesan Mohit N. Shivdasani Alastair Stacey Mathilde Escudie Samantha Lichter Robert K. Shepherd Steven Prawer 《Artificial organs》2016,40(3):E12-E24
Successful visual prostheses require stable, long‐term attachment. Epiretinal prostheses, in particular, require attachment methods to fix the prosthesis onto the retina. The most common method is fixation with a retinal tack; however, tacks cause retinal trauma, and surgical proficiency is important to ensure optimal placement of the prosthesis near the macula. Accordingly, alternate attachment methods are required. In this study, we detail a novel method of magnetic attachment for an epiretinal prosthesis using two prostheses components positioned on opposing sides of the retina. The magnetic attachment technique was piloted in a feline animal model (chronic, nonrecovery implantation). We also detail a new method to reliably control the magnet coupling force using heat. It was found that the force exerted upon the tissue that separates the two components could be minimized as the measured force is proportionately smaller at the working distance. We thus detail, for the first time, a surgical method using customized magnets to position and affix an epiretinal prosthesis on the retina. The position of the epiretinal prosthesis is reliable, and its location on the retina is accurately controlled by the placement of a secondary magnet in the suprachoroidal location. The electrode position above the retina is less than 50 microns at the center of the device, although there were pressure points seen at the two edges due to curvature misalignment. The degree of retinal compression found in this study was unacceptably high; nevertheless, the normal structure of the retina remained intact under the electrodes. 相似文献
156.
157.
Allison Given Chunyk Alison Joyce Saloumeh K. Fischer Mark Dysinger Alvydas Mikulskis Andreas Jeromin Rosemary Lawrence-Henderson Dana Baker David Yeung 《The AAPS journal》2018,20(1):10
An in-depth evaluation of the Quanterix© Simoa? platform was undertaken by scientists from the AAPS Emerging Technologies Focus Group to determine the overall performance of the technology as well as provide guidance to future users. In order to test the platform in a non-GLP bioanalytical setting, a cross-site evaluation of the Quanterix IL-6 biomarker kit was performed. Parameters tested during this evaluation included sensitivity, accuracy and precision, and parallelism in human serum from normal individuals. The results demonstrated improved sensitivity compared to the claimed sensitivity of other commercially available IL-6 kits and showed excellent site-to-site reproducibility. Observed issues included difficulties with system reliability and a lack of parallelism and specificity in a subset of samples. Overall, these results demonstrate that while there are challenges to the Simoa platform this technology offers automation capabilities and excellent sensitivity that enhance bioanalysis especially of low-abundance analytes. 相似文献
158.
159.
160.
She RC Stevenson J Phansalkar AR Hillyard DR Litwin CM Petti CA 《Diagnostic microbiology and infectious disease》2007,58(3):333-335
Clinicians use molecular tests to detect Herpesviridae from blood without fully appreciating limitations of testing. Studies are needed to enhance our understanding of the impact of Herpesviridae latency on molecular testing. We retrospectively performed quantitative Epstein-Barr virus (EBV) on sera from patients between the ages of 1 and 30 who demonstrated serologic evidence of acute EBV (n = 50) or remote EBV (n = 50) infection. Epstein-Barr virus DNA was detected in 70% of acutely infected and 4% of remotely infected patients. Sera from acutely infected patients had higher EBV copy number than convalescent sera. Our results suggest that serology should be performed as the initial diagnostic test for acute EBV. The role for polymerase chain reaction in immunocompromised patients with impaired antibody responses or as a 2nd-line diagnostic test when serologic results are equivocal deserves further study. 相似文献