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Sir, The comment of Attilio Di Spiezio Sardo et al. was very interesting.They reported the results of their studies on the effects ofintranasal and transdermal 相似文献
13.
A Ferlito G Caruso 《ORL; journal for oto-rhino-laryngology and its related specialties》1991,53(2):116-119
An extremely rare case of synovial sarcoma localized in the larynx is reported together with a review of 6 similar neoplasms previously reported in this unusual region. In this case, the patient is still tumor free 16 years after therapy. 相似文献
14.
C Caruso G Di Lorenzo M A Modica G Candore M R Portelli G Crescimanno A Ingrassia G B Sangiorgi A Salerno 《Mechanisms of ageing and development》1991,59(1-2):27-35
The evidence from several studies indicates that as individuals age, they may display immune dysfunctions, mostly T cell dysfunctions. Recently, a soluble form of the receptor for interleukin-2 (IL-2) (sIL-2R) has been demonstrated in human sera and in vitro stimulated culture supernatants from human T lymphocytes. In the present paper, we report in vitro sIL-2R production from peripheral blood mononuclear cells in elderly subjects. The results show that no difference exists for unstimulated cultures, whereas after mitogen stimulation the elderly subjects showed the lowest values compared with young ones. These findings suggest that sIL-2R may provide a new tool for the study of T lymphocyte dysfunctions in old age. 相似文献
15.
S Plescia G Daidone D Raffa M L Bajardi A Caruso V Cutuli M Amico-Roxas 《Il Farmaco; edizione pratica》1992,47(4):465-475
A number of new 3-(isoxazol-5-yl)-quinazolin-4(3H)-ones was prepared and tested, together a few analogues previously obtained, for their analgesic, antipyretic and antiinflammatory activities, as well as for their acute toxicity and ulcerogenic effects. In the carrageenan rat foot edema model one of the tested compounds showed activity and LD50 comparable to that of ASA, but the ulceration index approximated zero value. 相似文献
16.
Driven by research findings regarding the positive relationship between training and enhancement of services, as well as literature on adult learning, the New England Head Start Teaching Center (NEHSTC) was created in 1992 to test the efficacy of participatory, hands-on training. The purpose of this paper is to examine the outcome evaluation results from 4 years of training at the NEHSTC, 1 of 14 federally funded sites, as well as to discuss the implications for delivering this type of participatory training throughout Head Start. Findings suggest that the NEHSTC was successful in implementing high quality, participatory training within the context of an ongoing Head Start program. Head Start staff who participated in the NEHSTC trainings demonstrated gains in knowledge, skills, and expertise compared to similar Head Start employees who did not receive training. Results also reveal a sustained effect of training over time, with NEHSTC participants continuing to demonstrate enhanced knowledge and skills 6 months after training. Similar positive outcomes of training were found for staff with varying levels of experience and holding different Head Start positions. Thus the participatory, hands-on training implemented by the NEHSTC was found to produce positive and lasting outcomes for diverse Head Start staff. An effective and cost efficient model of training Head Start personnel is particularly relevant and timely as Head Start strives to establish universal quality and expansion of services in the 21st Century. The findings are also relevant for improving the quality of all early care and education programs. 相似文献
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M J Jaffe R C Caruso F M de Monasterio R B Nussenblatt 《American journal of optometry and physiological optics》1987,64(5):373-376
The human rod and cone systems have different spectral and adaptive sensitivities. Ganzfeld electroretinogram responses show that chronic eyelid closure, such as extensive symblepharon, can lead to dark-adaptation of the rods but simultaneously permit light-adaptation of the cones of the same eye. This effect is due to the red-filtering properties of the closed eyelid and the differential sensitivity of the two photoreceptor systems to the long wavelengths. 相似文献
19.
L Santoro A Perretti A Filla G De Michele B Lanzillo F Barbieri C Crisci P G Rippa G Caruso 《Journal of the neurological sciences》1992,113(1):43-49
An electrophysiologic and histologic study was performed on 18 patients affected by early onset cerebellar ataxia with retained tendon reflexes (EOCA). Sensory and motor conduction velocity (SCV, MCV) was measured along peripheral nerves in all patients, somatosensory (SSEP) and brainstem auditory evoked potentials (BAEP) were recorded in 13; cortical stimulation (CS) in 12, and sural nerve biopsy in 4 patients were also performed. The results as a whole allow a division of EOCA patients into 2 groups: with (7 patients) and without (11 patients) peripheral neuropathy. Among EOCA patients with neuropathy a differential diagnosis with Friedreich's disease patients was not possible according to BAEPs and CS, while SSEPs could differentiate 2 out 5 patients in whom they were performed. 相似文献
20.
Rosario Reyes Melissa Haendel Deanna Grant Ellie Melancon Judith S Eisen 《Developmental dynamics》2004,229(1):30-41
Rohon-Beard cells are large, mechanosensory neurons located in the dorsal spinal cord of anamniote vertebrates. In most species studied to date, these cells die during development. We followed labeled Rohon-Beard cells in living zebrafish embryos and found that they degenerate slowly, over many days. During degeneration, the soma shrinks and finally disappears, and the processes become beady in appearance and finally break apart, but they do not retract. Zebrafish Rohon-Beard cells apparently fragment their DNA, as revealed by terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) labeling, before undergoing degenerative morphologic changes. We also followed the development of labeled dorsal root ganglion neurons, as they are developing at the same stages that Rohon-Beard cells are degenerating. We found that, although axons of both cell types extend into similar regions, Rohon-Beard cells degenerate normally in mutants lacking dorsal root ganglia, providing evidence that interactions between the two cell types are not responsible for Rohon-Beard cell degeneration. Developmental Dynamics 229:30-41,2004. 相似文献