Fractures of the extremely atrophic mandible

Fracture treatment of the extremely atrophic mandible is a challenge to the surgeon because of the special problems and complications. A reliable method is the internal fixation technique with multiple split rib grafts. By use of immediate split rib bone grafting secondary revisions and reconstructions may be avoided. The technique and rationale are discussed.     

肌松药物巴氯芬类似物的合成及其构效关系的研究

为研究解痉肌松药巴氯芬类似物的构效关系,合成了巴氯芬类似物15个,其中8个化合物是首次报道。采用小白鼠热板法及对抗吗啡竖尾反应实验评价目标化合物的镇痛和肌松作用。筛选结果表明:部分化合物有肌松和镇痛作用,其中Ⅰb,Ⅱb,Ⅲa和Ⅲc的镇痛作用较好,Ⅰd,Ⅱb,Ⅲa和Ⅲb的肌松作用较好,但均未超过巴氯芬。根据本研究及前人的研究结果,提出巴氯芬与GABA_B受体结合取决于巴氯芬分子中氨基、羧基和苯环三种基团。     

Collagenous colitis: an electron microscopic study including comparison with the chronic fibrotic stage of ulcerative colitis

Light and electron microscopic studies of 14 cases of collagenous colitis are reported. Comparative electron microscopic examinations were carried out on 13 cases of ulcerative colitis in the chronic fibrotic stage of the disease. Separation of pericryptal fibroblasts which showed enhanced fibre-forming activity, proliferation of myofibroblasts, accumulation of mast cells and a pericapillary collagen accumulation were noted in both groups. Based on these results, collagenous colitis was considered to result from scar formation secondary to previous superficial inflammation.     

脱氧胆酸钠对麦角菌 Claviceps purpurea 94002 (EKP_N94002)产生 α-麦角隐亭的刺激作用

脱氧胆酸钠对麦角菌Ｃｌａｖｉｃｅｐｓｐｕｒｐｕｒｅａ９４００２（ＥＫＰＮ９４００２）产生α麦角隐亭的刺激作用朱平何惠霞陈世智（中国医学科学院、中国协和医科大学药物研究所，卫生部天然药物生物合成重点实验室，北京１０００５０）麦角菌属（Ｃｌａｖｉｃｅｐ...     

外源性雄激素致女性假两性畸形1例

０　引言　女性假两性畸形是性别异常中的常见类型之一,绝大多数是因先天性肾上腺皮质增生所致,而极少部分可由于妊娠早期母体内雄激素过多所致．此病例即为外源性雄激素所致女性假两性畸形,对其积极诊治对恢复今后的性生活和生育能力极为重要．１　病例报告　女,１４...     

毛白杨化学成分的研究

从毛白杨(Populus tomentosa Carr.)的叶中分得一个新的黄酮类化合物,鉴定为洋芹素-7-O-(6″-O-p-羟基肉桂酰)-B-D-吡喃葡萄糖甙(Ⅰ),同时还分得四个已知成分分别鉴定为水杨甙(salicin,Ⅱ)、2″-苯甲酰水杨甙(tremulodin,Ⅲ)、特里杨甙(tremulacin,Ⅳ)和胡萝卜甙(dauvasterol,Ⅴ)。     

CCU病房患者应激状态下发生精神异常2例

1　临床资料　患者,A,男,81岁,西安市人,农民,主因间断胸闷、气短、双下肢浮肿8mo余,加重10d于1999-12-10急诊收住西京医院心内科CCU病房.入院查体:BP19.3/13.3kPa,神志清,端坐位呼吸,查体合作,口唇紫绀,肝颈反流征(+),双肺布满干湿罗音,以中下肺野中小水泡音为主,心界左扩,心率75次·min-1,律齐,心前区可闻及级收缩期杂音,肝大肋下2指,生理反射存在,病理反射未引出.入院后心电图示:心肌供血不足.胸片提示:心影大,心胸比0.69,肺瘀血.入院诊断:1高血压病级、高心病、急性左心衰.2冠心病.1999-12-12因目睹邻床青年患者病危抢救全过程,于当…