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排序方式: 共有4103条查询结果,搜索用时 15 毫秒
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Retention strategies for health disparities preventive trials: findings from the Early Childhood Caries Collaborating Centers 下载免费PDF全文
Raul I. Garcia DMD MMedSc Tamanna Tiwari BDS MDS MPH Francisco Ramos‐Gomez DDS MS MPH Brenda Heaton MPH PhD Mario Orozco DDS MPH MBA Margaret Rasmussen MPH Patricia Braun MD MPH Michelle Henshaw DDS MPH Belinda Borrelli PhD Judith Albino PhD Courtney Diamond BS Christina Gebel MPH Terrence S. Batliner DDS MBA Judith C. Barker PhD Steven Gregorich PhD Stuart A. Gansky DrPH 《Journal of public health dentistry》2017,77(1):63-77
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Yuritzi Santillán-Hernández Enory Almanza-Miranda Winnie W Xin Kendrick Goss Aurea Vera-Loaiza María T Gorráez-de la Mora Raul E Pi?a-Aguilar 《World journal of gastroenterology : WJG》2015,21(3):1001-1008
Lysosomal acid lipase(LAL) deficiency is an underrecognized lysosomal disease caused by deficient enzymatic activity of LAL.In this report we describe two affected female Mexican siblings with early hepatic complications.At two months of age,the first sibling presented with alternating episodes of diarrhea and constipation,and later with hepatomegaly,elevated transaminases,high levels of total and low-density lipoprotein cholesterol,and low levels of highdensity lipoprotein.Portal hypertension and grade 2 esophageal varices were detected at four years of age.The second sibling presented with hepatomegaly,elevated transaminases and mildly elevated lowdensity lipoprotein and low high-density lipoprotein at six months of age.LAL activity was deficient in both patients.Sequencing of LIPA revealed two previously unreported heterozygous mutations in exon 4:c.253C>A and c.294C>G.These cases highlight the clinical continuum between the so-called Wolman disease and cholesteryl ester storage disease,and underscore that LAL deficiency represents a single disease with a degree of clinical heterogeneity. 相似文献
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Raul Caetano 《Addiction (Abingdon, England)》2015,110(9):1380-1380
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A Clinical Validation of Self‐Reported Periodontitis Among Participants in the Black Women’s Health Study 下载免费PDF全文
Brenda Heaton Nicholas B. Gordon Raul I. Garcia Lynn Rosenberg Sharron Rich Matthew P. Fox Yvette C. Cozier 《Journal of periodontology》2017,88(6):582-592
Background: There is a paucity of data on the validity of self‐report of periodontal disease in African Americans. The Black Women’s Health Study (BWHS), a United States national cohort study of 59,000 black women followed via mailed questionnaires since 1995, offered the opportunity to clinically validate self‐reported periodontitis among a sample of participants. Methods: Oral health questionnaires were sent to study participants residing in Massachusetts. Respondents living in the Boston metro area were invited for clinical examination. Self‐reports were compared with clinical data obtained from the 77 women (mean age: 59 years) who were examined. The authors examined the predictive ability of individual and combined questionnaire items with respect to clinical periodontal disease severity. Validation parameters were calculated for each question, and receiver operating characteristic statistics were generated to compare questionnaire items. Results: Periodontitis prevalence in the validation sample was 24% for severe periodontitis and 61% for moderate disease. Performance of individual questionnaire items with respect to predicting periodontitis was better for severe compared with moderate disease. Combinations of questionnaire items improved the predictive ability with respect to severe disease beyond that of individual questionnaire items. Conclusions: Prevalence of severe periodontitis was similar to other age‐comparable populations, without regard for race or sex, whereas prevalence of total periodontitis (moderate and severe) among women of similar age and/or race was much higher. Predictive ability of questionnaire items assessed in the BWHS was similar to that in other studies. 相似文献
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