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61.
Saraceno Lorenzo Susani Emanuela Laura Marazzi Maria Raffaella Moioli Maria Cristina Agostoni Elio Clemente Protti Alessandra 《Neurological sciences》2021,42(12):4881-4884
Neurological Sciences - Literature data reporting SARS-CoV-2 infection in multiple sclerosis (MS) patients recently treated with immunodepleting agents as cladribine and alemtuzumab are very... 相似文献
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Donaldson Kandace Huntington Alyssa De Vita Raffaella 《Annals of biomedical engineering》2021,49(8):1788-1804
Annals of Biomedical Engineering - The uterosacral ligaments (USLs) are important anatomical structures that support the uterus and apical vagina within the pelvis. As these structures are... 相似文献
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Raffaella Santi Alessandro Franchi Valeria Saladino Massimo Trovati Giovanna Cenacchi Massimo Squadrelli-Saraceno Gabriella Nesi 《Head and neck pathology》2015,9(2):300-304
Paragangliomas (PGs) of the head and neck region are typically benign, slow-growing neuroendocrine tumours. At times, they may exhibit unusual histological features, such as prominent stromal sclerosis (sclerosing PG), which may raise concerns of malignancy. We describe a case of sclerosing PG of the carotid body, emphasizing the value of immunohistochemical stains for differential diagnosis. A 43-year-old woman presented with a painless lump on the neck. A magnetic resonance imaging scan demonstrated a hypervascular lesion of the carotid body, which was surgically excised. Grossly, the lesion measured 1.8 cm at maximum diameter. On microscopic examination, irregular nests and tiny bundles of neoplastic cells were found between thick bands of fibrous tissue. Focal nuclear cytomegaly and marked pleomorphism were noted. Neoplastic cells proved to be immunoreactive for chromogranin, synaptophysin and neuron specific enolase, but negative for cytokeratins, smooth muscle actin and CD34. Ultrastructurally, numerous mitochondria, rough endoplasmic reticulum structures and endocrine granules were seen in the cytoplasm of the tumour cells. On consideration of the above-mentioned clinico-pathological and ultrastructural findings a diagnosis of sclerosing PG was established. Sclerosing PG is a rare entity which may mimic a malignant neoplasm. The recognition of this unusual morphological variant of PG, together with appropriate immunostains, leads to the correct diagnosis. 相似文献
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Maternal uniparental isodisomy (iUPD) of chromosome 4 in a subject with mild intellectual disability and speech delay 下载免费PDF全文
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Microdeletion of 12q24.31: Report of a girl with intellectual disability,stereotypies, seizures and facial dysmorphisms 下载免费PDF全文
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