ACUTE EFFECTS OF ALCOHOL ON POWER DISTRIBUTION BETWEEN MAN AND WOMAN

An experiment was performed testing the hypothesis that thedistribution of outcome power and process power among a maleand female will change in favor of the male as a function offemale alcohol intoxication. Dyads were randomly assigned toeither an alcohol, a placebo or a control group and took partin a decision game. The respective influence on the actual decisionoutcome and on the decision process was estimated. Alcohol didnot affect the distribution of outcome power and the processwas only affected by a quantitative increase in number of utterancesand discussion time. The results were discussed in relationto theoretical models and sex-role typing.     

Laser catheter ablation of atrial flutter and of atrioventricular nodal reentrant tachycardia in a single session

This report describes an adolescent with refractory atrial flutter(AF) and atrioventricular (AV) nodal reentrant tachycardia whowas cured by Nd: YAG, 1064 nm, laser application. Two impactsof 30 s each (power 30 W and irradiated spot diameter 2.0–2.5mm), applied via a novel laser catheter system, abolished bothAF and AV nodal reentrant tachycardia. The procedure was withoutcomplications or recurrent arrhythmias.     

Alternate Ventriculo-Atrial Wenckebach Conduction during Ventricular Tachycardia

Although pacing-induced ventriculo-atrial (VA) Wenckebach conduction has been previously described, the occurrence of this phenomenon during ventricular tachycardia has received little attention. The latter is defined as 2:1 VA block in which the conducted beats show progressive lengthening of VA conduction until the sequence is terminated by two or three blocked ventricular beats. This phenomenon was observed in a 16-year-old boy who underwent electrophysiologic study for ventricular tachycardia as a late complication of surgical correction of tetralogy of Fallot. During pacing-induced ventricular tachycardia with a morphology similar to that of the spontaneous tachycardia, 8:4 alternating VA block was observed. This sequence suggested that the AV node was the site of block, the 2:1 block being located at the upper level, and the VA Wenckebach block at the lower level. Alternate VA Wenckebach conduction appears as a possible cause of variation in atrial depolarization intervals during ventricular tachycardias with short cycle lengths.     

Oral lesions of lupus erythematosus patients in relation to other chronic inflammatory oral diseases: an immunologic study

Abstract – The nature and distribution of mononuclear cells in non-ulcerated oral lesions of discoid (DLE) and systemic lupus erythematosus (SLE), were investigated and compared to other chronic inflammatory oral diseases (lichen planus (LP), contact lesion (CL), unspecified inflammation (UI), geographic tongue (GT), and leukoplakia (LK). For this purpose an immunoperoxidase technique based on staining with monoclonal antibodies was employed. In most LE specimens examined infiltrating cells consisted predominantly of a mixture of T cells (Leu 3a⁺ and Leu 2a⁺) that were distributed in the lamina propria, the submucosa, and occasionally also in the epithelium. In general, only few B cells were detected while macrophages were more frequent. In all LE specimens examined β₂-microglobulin expression was observed on a large proportion of cells including infiltrating mononuclear cells as well as resident keratinocytes. In addition, most infiltrating cells displayed MHC Class II antigens according to a pattern HLA-DR>DQ>DP. Interestingly, expression of Class II antigens was also observed on epithelial keratinocytes but was restricted to HLA-DR and -DP gene products (DR> >DP). HLA-DQ expression was never observed on keratinocytes. In most LE specimens studied a small proportion (<5%) of inflammatory cells had detectable interleukin-2 receptors (IL-2R) and/or transferrin receptors (transf-R). However, expression of transf-R was also observed on basal epithelial cells, being more pronounced in DLE than in SLE lesions. The above staining patterns observed in LE lesions, when compared to other chronic inflammatory oral lesions, did not disclose any striking differences that could support the specific diagnosis of LE. However, the findings of Class I and II MHC gene products on oral keratinocytes suggest an important accessory role for these cells in directing the migration of activated lymphoid cells in the epithelium in chronic inflammatory lesions of the oral mucosa.     

Valve Selection and Choice in Surgery of Endocarditis

The experience of the German Heart Center with valve selection and choice of size of prostheses for aortic root endocarditis is hereby reported. This experience includes 37 cases of aortic root endocarditis between 1986 and 1989. Mechanical, bioprosthetic, and homograft valves were used depending on the size, annular pathology, and general conditions related to the patient's medical history. Operative techniques are presented. Regardless of the type of valve replacement device, extensive annular destruction indicates a difficult and complex operation with long-term early and late results inferior to those in patients without annular abscess.     

Waardenburg Syndrome Type I with Heterochromia Iridis and Circumscribed Hypopigmentation of the Skin

Abstract: We report a 3‐year‐old girl with autosomal dominant inherited Waardenburg syndrome type I showing circumscribed hypopigmentation of the skin, heterochromia iridis, sensorineural deafness, and dental aberrations. Clinical diagnosis was confirmed by the identification of an underlying missense mutation (C811T) in the PAX3 gene. Early diagnosis of Waardenburg syndrome among children with pigment anomalies enables a successful interdisciplinary medical care.     

Successful Topical Treatment of Sorafenib-Induced Hand–Foot Skin Reaction in a Child with Hepatocellular Carcinoma

Abstract:  Orally active kinase inhibitors such as Sorafenib are known to elicit cutaneous side effects in the majority of adult patients, whereas specific cutaneous complications of this agent have not been described in children so far. We here present the first pediatric case of Sorafenib-induced hand-foot-skin reaction and its successful topical therapy facilitating continuation of kinase inhibitor treatment.