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11.
Rice varieties with similar amylose content differ in starch digestibility and glycemic response in humans 总被引:7,自引:0,他引:7
L N Panlasigui L U Thompson B O Juliano C M Perez S H Yiu G R Greenberg 《The American journal of clinical nutrition》1991,54(5):871-877
Three high-amylose rice varieties, IR42, IR36, and IR62, with similar chemical composition including amylose content (26.7-27.0%), were cooked under the same conditions and tested for in vitro digestibility as well as blood glucose and insulin responses in healthy human volunteers. The starch-digestion rate and the glycemic and insulin responses were the highest in IR42, followed by IR36 and, then IR62. The differences were not due to unabsorbed carbohydrate but were related to their physicochemical properties, such as gelatinization temperature, minimum cooking time, amylograph consistency, and volume expansion upon cooking. When the three varieties were cooked for their minimum cooking time, they had the same degree of gelatinization and their starch-digestion rates and glycemic responses were similar. We conclude that amylose content alone is not a good predictor of starch-digestion rate or glycemic response. Rice varieties with similar high-amylose contents can differ in physicochemical (gelatinization) properties and this, in turn, can influence starch digestibility and blood glucose response. 相似文献
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De Leo V; Morgante G; Lanzetta D; D'Antona D; Bertieri RS 《Human reproduction (Oxford, England)》1997,12(2):357-360
We report the results of administration of danazol after suspension of
gonadotrophin-releasing hormone analogue (GnRHa) therapy for uterine
myomas. A total of 21 women with uterine myomas was treated with 100 mg
danazol for 6 months after GnRHa therapy. Uterine volume and endocrine
status were monitored monthly by ultrasound and assay of plasma
gonadotrophins, oestradiol and progesterone. The results show a rebound of
uterine volume about 30% less than in controls at the end of danazol
therapy. Menstrual cyclicity returned after 65 +/- 3 days in 16 subjects
and five patients remained amenorrhoeic. Hormone assays confirmed renewed
ovarian function in the women whose menstrual periods returned. Bone
mineral content was substantially reduced during GnRHa treatment but
improved significantly during danazol therapy even in the women who
remained amenorrhoeic. These results show the utility of danazol in
prolonging the therapeutic effects of GnRHa. The mechanism by which danazol
inhibits rebound of uterine volume may be due to its antiprogesterone
effects on uterine myomas.
相似文献
15.
Hilda A. Perez Carmen Bracho Mirtha Romano Mercedes De la Rosa 《Parasitology research》1997,83(3):246-251
A monoclonal antibody raised by immunization of BALB/c mice with erythrocytic stages of Plasmodium vivax was shown to react with asexual erythrocytic stages of P. chabaudi. The cross-reactivity molecules are antigens of 200 and 148 kDa in P. vivax and of 190 and 70 kDa in P. chabaudi. Immunofluorescence studies of the erythrocytic stages of P. vivax and P. chabaudi indicated that expression of these antigens increased as the parasites' developed from the ring stage to the schizont stage.
In the mature trophozoites of P. chabaudi, immunoelectron microscopy revealed clusters of antigen distributed in the cytoplasm of the parasitized erythrocyte. In the
schizont, packets of antigen were found associated with the parasitophorous vacuole and the cytoplasm of the infected host
cell.
Received: 19 March 1996 / Accepted: 28 August 1996 相似文献
16.
The effects of external beam radiotherapy on endocrine function in patients with carcinoma of the prostate 总被引:2,自引:0,他引:2
Serum levels of testosterone, dihydrotestosterone, and follicle-stimulating and luteinizing hormones were determined prospectively in 59 patients with carcinoma of the prostate treated curatively with external beam radiotherapy. Hormone levels were determined before the initiation of therapy and up to 2 years following completion of therapy. Testosterone levels remained unchanged but dihydrotestosterone levels decreased slightly. Follicle-stimulating and luteinizing hormone levels increased significantly during therapy and remained elevated for up to 2 years after therapy. These findings are consistent with low dose irradiation of the testis. 相似文献
17.
The prognostic significance of acute renal failure after renal transplantation in patients treated with cyclosporin 总被引:2,自引:0,他引:2
Perez Fontan M; Rodriguez-Carmona A; Bouza P; Valdes F 《QJM : monthly journal of the Association of Physicians》1998,91(1):27-40
We studied 733 cadaveric renal transplant patients (747 transplants) under
cyclosporin immunosuppression, to: (i) establish the risk profile for acute
renal failure (ARF) after renal transplantation in a unit using many
sub-optimal donors; (ii) assess the long-term prognostic relevance of ARF;
and (iii) explore the synergistic prognostic significance of delayed graft
function and acute rejection during the early post-transplant period.
Transplanting from a non-heart-beating or elderly donor, protracted cold
ischaemia, haemodialysis immediately before transplant surgery, poor HLA
matching, and grafting to a hypersensitized recipient without residual
renal function, all independently predicted delayed graft function. This
delay had no detrimental effect on patient or graft survival, but prolonged
ARF was associated with increased mortality from infection. Late markers of
graft dysfunction (poor graft function, proteinuria, hypertension) were
highly prevalent among grafts affected by ARF, specially in prolonged ARF.
Delayed graft function and early acute rejection showed a definite, albeit
not strong, additive impact on late graft survival, and also on the
prevalence of late markers of graft dysfunction.
相似文献
18.
C Albet J M Fernandez E Rozman J A Perez A Sacristan J A Ortiz 《Journal of pharmaceutical and biomedical analysis》1992,10(2-3):205-211
A high-performance liquid chromatographic method is developed for the determination of bulk sertaconazole nitrate and related compounds (potential impurities and degradation products) as well as a sertaconazole nitrate cream formulation. A 10-microns Spherisorb CN column is used along with a mobile phase consisting of acetonitrile and aqueous 0.01 M sodium phosphate (37:63, v/v). The sertaconazole nitrate peak is monitored at a wavelength of 260 nm; the retention time being 19.3 min. The detector response for sertaconazole nitrate is linear over the concentration range from 64 to 96 micrograms ml-1. The method is found to be sufficiently selective for the reliable determination of related compounds, FI-7001, FI-7009 and FI-7011, as indicated by same-day and between-day relative standard deviations (RSD) for replicate assays of 1.72% (n = 9) and 2.17% (n = 24), respectively. The application of this method to a cream formulation of sertaconazole nitrate is found to give a mean percentage recovery of 99.4% with RSD of 1.14% (n = 9); none of the cream vehicle peaks are found to interfere with the determination of sertaconazole nitrate. 相似文献
19.
Abnormal muscle and skin mitochondria in family with myoclonus, ataxia, and deafness (May and White syndrome).
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J Vaamonde J Muruzabal T Tun N Perez J Artieda M Rodriguez J A Obeso 《Journal of neurology, neurosurgery, and psychiatry》1992,55(2):128-132
A mother and two of her daughters had deafness and cortical reflex myoclonus; the mother also had mild truncal ataxia. Muscle and skin biopsy specimens revealed abundant ragged-red fibres and abnormal mitochondria. The son of one of the daughters had sensorineural deafness. Three other grandchildren were asymptomatic. The two daughters also had diabetes mellitus, hypertension and cardiomyopathy. Another daughter died of renal failure. The mother lost her hearing in her 70s, one daughter in her 30s, and the other daughter and the grandson in their 20s. The mother has had transient episodes (24-48 hours) of temporal disorientation, severe action myoclonus, and ataxia for about eight years. This is the first reported family with inherited deafness, myoclonus, and ataxia with mitochondrial pathology. 相似文献
20.
Adverse outcomes of planned and unplanned pregnancies among users of natural family planning: a prospective study. 总被引:3,自引:1,他引:2
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A Bitto R H Gray J L Simpson J T Queenan R T Kambic A Perez P Mena M Barbato C Li V Jennings 《American journal of public health》1997,87(3):338-343
OBJECTIVES: The purpose of this study was to determine prospectively whether unplanned pregnancies are associated with adverse pregnancy outcomes among users of natural family planning. METHODS: Women who became pregnant while using natural family planning were identified in five centers worldwide: there were 373 unplanned and 367 planned pregnancies in this cohort. The subjects were followed up at 16 and 32 weeks' gestation and after delivery. The risks of spontaneous abortion, low birth-weight, and preterm birth were estimated after adjustment by logistic regression. RESULTS: The women with unplanned pregnancies were more likely to be at the extremes of age, to report more medical problems before and during the index pregnancy, and to seek antenatal care later in gestation than the women with planned pregnancies. However, women with planned pregnancies reported a higher rate of spontaneous abortion in previous pregnancies (28.8%) than did women with unplanned pregnancies (12.9%). There were no significant differences in the rates of spontaneous abortion, low birthweight, or preterm birth between the two groups. CONCLUSIONS: No increased risk of adverse pregnancy outcomes was observed among women who experienced an unplanned pregnancy while using natural family planning. 相似文献