全文获取类型
收费全文 | 19058篇 |
免费 | 3502篇 |
国内免费 | 144篇 |
专业分类
耳鼻咽喉 | 470篇 |
儿科学 | 573篇 |
妇产科学 | 514篇 |
基础医学 | 1667篇 |
口腔科学 | 361篇 |
临床医学 | 4230篇 |
内科学 | 3605篇 |
皮肤病学 | 457篇 |
神经病学 | 1549篇 |
特种医学 | 580篇 |
外科学 | 2288篇 |
综合类 | 572篇 |
现状与发展 | 2篇 |
一般理论 | 13篇 |
预防医学 | 3032篇 |
眼科学 | 344篇 |
药学 | 819篇 |
1篇 | |
中国医学 | 107篇 |
肿瘤学 | 1520篇 |
出版年
2023年 | 480篇 |
2022年 | 215篇 |
2021年 | 491篇 |
2020年 | 641篇 |
2019年 | 410篇 |
2018年 | 811篇 |
2017年 | 769篇 |
2016年 | 803篇 |
2015年 | 910篇 |
2014年 | 966篇 |
2013年 | 1404篇 |
2012年 | 922篇 |
2011年 | 869篇 |
2010年 | 790篇 |
2009年 | 919篇 |
2008年 | 702篇 |
2007年 | 700篇 |
2006年 | 749篇 |
2005年 | 618篇 |
2004年 | 585篇 |
2003年 | 555篇 |
2002年 | 523篇 |
2001年 | 439篇 |
2000年 | 321篇 |
1999年 | 346篇 |
1998年 | 375篇 |
1997年 | 382篇 |
1996年 | 398篇 |
1995年 | 334篇 |
1994年 | 270篇 |
1993年 | 203篇 |
1992年 | 262篇 |
1991年 | 279篇 |
1990年 | 229篇 |
1989年 | 252篇 |
1988年 | 229篇 |
1987年 | 206篇 |
1986年 | 199篇 |
1985年 | 187篇 |
1984年 | 158篇 |
1983年 | 146篇 |
1982年 | 109篇 |
1981年 | 132篇 |
1980年 | 100篇 |
1979年 | 96篇 |
1978年 | 100篇 |
1977年 | 98篇 |
1976年 | 98篇 |
1974年 | 83篇 |
1972年 | 87篇 |
排序方式: 共有10000条查询结果,搜索用时 187 毫秒
51.
52.
BACKGROUND: The QT interval on the ECG is prolonged by more than 50 marketed drugs, an effect that has been associated with syncope and/or sudden cardiac death due to an arrhythmia. Because changes in heart rate also change the QT interval, it has become standard practice to use a correction formula, such as the Bazett formula, to normalize the QT interval to a heart rate of 60 bpm, that is, the rate-corrected QT or QTc. Numerous other formulas have been devised to make this correction, including the Fridericia, Hodges, and Framingham formulas. OBJECTIVES: The purpose of this study was to investigate how the Bazett formula and three other formulas influence assessment of the QT-prolonging effect of the potassium channel-blocking drug ibutilide. METHODS: Using a standardized physical activity protocol, the QT interval was assessed over a broad range of heart rates before and after an infusion of ibutilide (4.75 microg/kg) that produced a stable 15- to 20-ms QT prolongation in consenting normal subjects (9 men and 9 women). The QT interval was measured digitally over a range of heart rates from 60 to 120 bpm, and then four correction formulas (Bazett, Fridericia, Framingham, or Hodges) were applied. The uncorrected change in QT interval due to ibutilide was compared with the change using each of the formulas by repeated measures analysis of variance. RESULTS: At heart rates from 60 to 120 bpm, the Bazett and Fridericia correction formulas overestimated the change in QT in both men and women (P <.001). However, the Framingham and Hodges formulas did not alter the accuracy of the assessment of QT interval change. CONCLUSION: Rate correction of QT intervals using the standard Bazett and Fridericia formulas can introduce significant errors in the assessment of drug effects on the QT interval. This has implications for the clinical assessment of drug effects and for the safety assessment of new drugs under development. 相似文献
53.
54.
Rufus S. HoweCPT AN BSE BSN RN-C Claudia ChrlstmanCPT AN MS BA BSN RN-C 《Journal of the American Academy of Nurse Practitioners》1991,3(1):35-41
Noninsulin dependent diabetes (type II diabetes) is a chronic disease characterized by hyperglycemia. Clients can generally be controlled by diet and exercise or a combination of diet, exercise, and oral hypoglycemic agents. When this therapy is not effective in controlling the hyperglycemia, the health care provider must choose to initiate insulin therapy. Outpatient initiation of insulin is an alternative to hospitalization in the type II diabetic client. Clinical guidelines for the initiation of insulin on an outpatient basis and management of the diabetic client are presented. 相似文献
55.
The current study evaluated psychosocial variables that may contribute to the experience of headache in college adults. One hundred ninety-nine participants, 103 women and 96 men, completed head pain logs for 4 weeks after completing measures assessing psychosocial variables. Multiple regression analyses indicated that level of emotional functioning, perception of stress, and gender were predictive of future headache frequency, intensity, and duration. Family history and health habits did not predict headache activity. These findings are consistent with research investigating psychosocial variables and headache activity. 相似文献
56.
Karen A Luker PhD BNurs RGN RHV NDNCert Kinta Beaver BA RGN DPSN Samuel J Leinster BSc MD FRCS R Glynn Owens BTech DipPsych DPhil AFBPsS Lesley F Degner PhD RN Jeffrey A Sloan PhD BSc 《Journal of advanced nursing》1995,22(1):134-141
Nurses can play a key role in patient education, including providing patients with useful and approrate information Rather than focusing on the process of education or information giving by nurses, this study places emphasis on the content of that information by taking the patients'perspective and asking the patients themselves what particular types of information are perceived as important at a specific point in time The aim of the study was to explore what particular types of information were important to women newly diagnosed with breast cancer, to enable nurses and other health care professionals to utilize their time as effectively as possible and provide a high-quality service to individuals in their care Women with breast cancer (a mean of 2 5 weeks from diagnosis) were interviewed and asked to compare items of information The items of information were presented m pairs and the women stated a preference for one item in that pan- Thirty-six pairs were presented in total The analysis involved the use of a Thurstone scaling model, which allowed rank ordermgs, or profiles of information needs, to be developed, reflecting the perceived importance of each item Information about the likelihood of cure, the spread of the disease and treatment options were perceived as the most important items of information at the tune of diagnosis Other information needs, in order of descending priority, included information about the risk to family, side-effects 相似文献
57.
A comparison of the stressors experienced by parents of intubated and non-intubated children 总被引:3,自引:0,他引:3
Caroline Haines BN RGN RSCN Christine Perger BHSc Sue Nagy RN BA FRCNA FCN 《Journal of advanced nursing》1995,21(2):350-355
When children are ill enough to require admission to paediatric intensive care, parents may become distressed about their child's medical condition and this distress may be compounded by the unfamiliar nature of the highly technological environment Parents of children who are sick enough to warrant intubation are particularly likely to be exposed to a frightening array of technological equipment Seventy-one parents of intubated and non-intubated children completed the Parental Stressor Scale Paediatnc Intensive Care Unit (PSS PICU) Overall the findings suggest that parents were most distressed (a) by the painful procedures to which their children were subjected, (b) by the sights and sounds of the intensive care unit and (c) by their children's reactions to intensive care The behaviour of staff towards parents and the way that staff communicated with them caused the least distress When the levels of stress reported by parents of intubated children were compared with those reported by parents of non-intubated children, different patterns of stress were found Painful procedures were a source of greater stress to parents of intubated children whereas the behaviour of staff and the children's reactions to the intensive care experience caused greater stress to the parents of the non-intubated children In general the findings suggest that the needs of parents of non-intubated children are being overlooked, with staff focusing more of their attention on the parents of intubated children 相似文献
58.
T J Francis R R Pearson A G Robertson M Hodgson A J Dutka E T Flynn 《Undersea biomedical research》1988,15(6):403-417
Many aspects of central nervous system (CNS) decompression sickness (DCS) are poorly understood, including the temporal pattern of its presentation and the pathogenic mechanisms involved in the development of the disease. Using case histories and clinical series published in the literature and retrieved from treatment center records, this study is an attempt to define the interval between surfacing from a hyperbaric exposure and the onset of symptoms of CNS DCS. The results of 1070 cases of human CNS DCS were included in the study. The results show that the disease generally occurs rapidly: over 50% became symptomatic within 10 min of returning to 1 ATA, and in only 15% of cases was the onset of symptoms delayed for more than 1 h. Cerebral DCS had a more rapid onset than spinal cord disease: 50% of cerebral cases became apparent within about 3 min and a similar proportion of spinal cord cases within about 9 min from surfacing. The influence of these results on the diagnosis and treatment of dysbaric illness, on the safety of certain diving practices, and on possible pathogenic mechanisms is discussed. 相似文献
59.
Wijeyesinghe E. C. R.; Hawkins T.; keavey Pauline M.; Wilkinson R. 《Nephrology, dialysis, transplantation》1988,3(2):209-213
The value of the Technetium-99m tin colloid (TTC) scan in thediagnosis of renal transplant rejection occurring more than1 month following transplantation was assessed. To our knowledge,use of this agent has not previously been reported. Gamma cameraimaging was performed on 15 occasions in 14 patients in whomplasma creatinine was rising and in three patients in whom renalfunction was stable. Both a qualitative and a quantitative assessmentof images was made. The radioactivity recorded over the graft at 1216 mmpost injection was expressed as a percentage of that recordedat 04 min. In the nine patients in whom graft perfusionwas adequate to allow interpretation of the TTC scan and inwhom rejection was diagnosed by biopsy (six cases) or on clinicalgrounds (three cases), the index ranged from 45 to 153%. Intwo patients the graft was poorly perfused and the accumulationof TTC was predictably low despite the presence of rejection.In the seven patients with either a stable creatinine or withrising creatinine not due to rejection, the index ranged from5 to 43%. Previously reported studies have shown that sulphur colloidsmay be of value in diagnosing graft rejection. This study suggeststhat Tc99m tin colloid may be regarded as a suitable alternativescanning agent and that some simplification of data collectionand analysis can be achieved. 相似文献
60.
H. Ono R. Akiyama Y. Sakamoto J. T. Pearson H. Tazawa 《Medical & biological engineering & computing》1997,35(4):431-435
As an avian embryo grows within a eggshell, the whole egg is moved by embryonic activity and also by the embryonic heartbeat.
A technical interest in detecting minute biological movements has prompted the development of techniques and systems to measure
the cardiogenic ballistic movement of the egg or ballistocardiogram. (BCG). In this context, there is interest in using an
electromagnetic induction coil (solenoid) as another simple sensor to measure the BCG and examining its possibility for BCG
measurement. A small permanent magnet is attached tightly to the surface of an incubated egg, and then the egg with the magnet
is placed in a solenoid. Preliminary model analysis is made to design a setup of the egg, magnet and solenoid coupling system.
Then, simultaneous measurement with a laser displacement measuring system, developed previously, is made for chicken eggs,
indicating that the solenoid detects the minute cardiogenic ballistic movements and that the BCG determined is a measure of
the velocity of egg movements. 相似文献