全文获取类型
收费全文 | 1341篇 |
免费 | 94篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 30篇 |
妇产科学 | 19篇 |
基础医学 | 198篇 |
口腔科学 | 69篇 |
临床医学 | 102篇 |
内科学 | 170篇 |
皮肤病学 | 28篇 |
神经病学 | 88篇 |
特种医学 | 100篇 |
外科学 | 218篇 |
综合类 | 85篇 |
预防医学 | 174篇 |
眼科学 | 32篇 |
药学 | 64篇 |
中国医学 | 1篇 |
肿瘤学 | 56篇 |
出版年
2021年 | 11篇 |
2019年 | 13篇 |
2018年 | 17篇 |
2017年 | 11篇 |
2016年 | 10篇 |
2015年 | 28篇 |
2014年 | 22篇 |
2013年 | 40篇 |
2012年 | 63篇 |
2011年 | 48篇 |
2010年 | 38篇 |
2009年 | 50篇 |
2008年 | 63篇 |
2007年 | 62篇 |
2006年 | 60篇 |
2005年 | 52篇 |
2004年 | 55篇 |
2003年 | 41篇 |
2002年 | 42篇 |
2001年 | 34篇 |
2000年 | 41篇 |
1999年 | 45篇 |
1998年 | 38篇 |
1997年 | 27篇 |
1996年 | 21篇 |
1995年 | 16篇 |
1994年 | 18篇 |
1993年 | 19篇 |
1992年 | 27篇 |
1991年 | 32篇 |
1990年 | 30篇 |
1989年 | 35篇 |
1988年 | 35篇 |
1987年 | 24篇 |
1986年 | 17篇 |
1985年 | 25篇 |
1984年 | 27篇 |
1983年 | 16篇 |
1982年 | 12篇 |
1981年 | 11篇 |
1980年 | 10篇 |
1979年 | 10篇 |
1978年 | 9篇 |
1976年 | 11篇 |
1975年 | 11篇 |
1974年 | 12篇 |
1972年 | 10篇 |
1971年 | 9篇 |
1970年 | 11篇 |
1969年 | 12篇 |
排序方式: 共有1441条查询结果,搜索用时 453 毫秒
61.
A case of dyskeratosis congenita in a 10-year-old white boy is reported. The triad of oral leukoplakia, nail dystrophy, and skin pigmentation was present. Other associated anomalies included dysphagia and varied immunoglobulin levels, although there was no evidence of anemia, pancytopenia, and ocular involvement. Since it may be associated with future malignant change, dyskeratosis congenita should be considered in all cases in which an obscure white lesion exists in the mouth. 相似文献
62.
Renal vein thrombosis can occur as a complication of nephrotic syndrome. We present the case of a young man with nephrotic syndrome caused by minimal change disease who developed acute inferior vena cava and left renal vein thrombosis. He was treated initially with intravenous heparin. Because of the persistence of severe left flank pain and gross hematuria, local infusion of recombinant tissue plasminogen activator was tried, with resolution of thrombi and subsidence of symptoms. Functional preservation of the involved kidney is good, as indicated by Tc-99m DMSA scan (involved kidney, 47.4%; uninvolved kidney, 52.6%). Anticoagulation is usually recommended as the treatment of choice in renal vein thrombosis. We believe that in cases with critical presentations, such as bilateral involvement, extension into inferior vena cava, acute renal failure, pulmonary embolism or severe flank pain, thrombolytic therapy should be considered as a second-line treatment if good response is not obtained with heparin. 相似文献
63.
64.
65.
Thomas H. Ogden 《Contemporary psychoanalysis》2013,49(3):346-371
The author describes his ongoing experience in creating an entirely new psychoanalytic training institute from the merger of two currently operating institutes. The goals, ideals, conflicts, and vicissitudes of the merger process are described, along with the more difficult and elusive effort to turn out skilled and emotionally balanced analysts who are, to whatever extent possible, also decent human beings. 相似文献
66.
Rob Ogden 《Forensic science, medicine, and pathology》2010,6(3):172-179
Wildlife DNA forensics is receiving increasing coverage in the popular press and has begun to appear in the scientific literature in relation to several different fields. Recognized as an applied subject, it rests on top of very diverse scientific pillars ranging from biochemistry through to evolutionary genetics, all embedded within the context of modern forensic science. This breadth of scope, combined with typically limited resources, has often left wildlife DNA forensics hanging precariously between human DNA forensics and academics keen to seek novel applications for biological research. How best to bridge this gap is a matter for regular debate among the relatively few full-time practitioners in the field. The decisions involved in establishing forensic genetic services to investigate wildlife crime can be complex, particularly where crimes involve a wide range of species and evidential questions. This paper examines some of the issues relevant to setting up a wildlife DNA forensics laboratory based on experiences of working in this area over the past 7 years. It includes a discussion of various models for operating individual laboratories as well as options for organizing forensic testing at higher national and international levels. 相似文献
67.
68.
Filla SA Winter MA Johnson KW Bleakman D Bell MG Bleisch TJ Castaño AM Clemens-Smith A del Prado M Dieckman DK Dominguez E Escribano A Ho KH Hudziak KJ Katofiasc MA Martinez-Perez JA Mateo A Mathes BM Mattiuz EL Ogden AM Phebus LA Stack DR Stratford RE Ornstein PL 《Journal of medicinal chemistry》2002,45(20):4383-4386
Amino diacid 3, a highly selective competitive GluR5 kainate receptor antagonist, exhibited high GluR5 receptor affinity and selectivity over other glutamate receptors. Its diethyl ester prodrug 4 was orally active in two models of migraine: the neurogenic dural plasma protein extravasation model and the nucleus caudalis c-fos expression model. These data suggest that a GluR5 kainate receptor antagonist might be an efficacious antimigraine therapy with a novel mechanism of action. 相似文献
69.
Interest in kainate receptors has increased over the past few years. Our understanding of their physiology and pharmacology has improved markedly since their original cloning and expression in the early 1990s. For example, agonist profiles at recombinant kainate receptors have been used to identify and distinguish kainate receptors in neurons. Furthermore, the development of selective antagonists for kainate receptor subtypes has increased our understanding of the functional roles of kainate receptors in neurons and synaptic transmission. In this review we described the activity of agonists and antagonists at kainate receptors and their selectivity profiles at NMDA and non-NMDA receptors. 相似文献
70.