Inapparent Double Puncture of the Femoral Artery and Vein An Important Complication of Temporary Cardiac Pacing by the Transf emoral Approach

An important complication of temporary cardiac pacing by the transfemoral approach. This report describes three cases of inapparent double puncture of the femoral artery and vein as a complication of the transfemoral approach for temporary cardiac pacing. This complication may lead to the passage of a pacing catheter to the right ventricle by way of the femoral artery and vein and may remain undiagnosed until the rigid outer sheath of the introducer set is withdrawn over the pacing catheter. Therefore, we recommend immediate withdrawal of the rigid outer sheath as soon as the catheter lies freely in the iliac vein or the inferior vena cava. If double puncture has occurred, arterial blood will leak around the pacing catheter. Control of arterial bleeding by local compression should not be attempted without removal of the pacing catheter.     

Double purse string suture technique for loop colostomy prolapse in infants

ABSTRACT. Loop colostomy in infants is a common procedure, performed mainly for lower large bowel obstruction. However, prolapse of the colostomy is a frequent complication. A double purse string suture technique is advocated to fix the prolapse, and the results have been encouraging.     

电针治疗大鼠慢性脊髓损伤疗效观察及分子机制的实验研究

目的 探索电针治疗慢性脊髓损伤的作用机理.方法 采用大鼠后路渐进性脊髓压迫动物模型,然后手术减压,并进行电针治疗.通过体诱发电位和BBB评分观察后肢功能,采用免疫组化和蛋白印迹法观察神经营养因子-3 （NT-3）及其受体（TrkC）的变化.结果 脊髓损伤后NT-3和TrkC在神经元及胶质细胞表达增强,经过电针治疗后, NT-3和TrkC在神经元和胶质细胞的表达下降.诱发电位检测和BBB评分显示,电针组疗效优于减压组（P〈0.05）.结论 电针治疗可促进脊髓损伤大鼠的行为功能恢复,这可能是通过内源性神经营养因子及其受体介导的.     

变频超声分型诊断阑尾炎的价值

目的探讨变频超声分型诊断阑尾炎的价值。方法应用超声的变频凸阵探头（2．6～6．5MHz）检查结合临床资料分型诊断阑尾炎218例，并将检查结果与手术及病理对照。结果保守治疗62例达到临床治愈；156例经手术及病理证实，超声诊断符合率95．5％（149／156）。超声分型诊断符合率：单纯型急性阑尾炎88．6％（31／35），化脓型急性阑尾炎94．8％（55／58），坏疽型急性阑尾炎86．5％（45／52），慢性阑尾炎发作型90．9％（10／11）。结论变频超声可动态观察阑尾炎的声像图变化，分型诊断阑尾炎能及时为临床正确选择治疗方案提供参考依据。     

药剂科药事管理在医院管理工作中重要作用的探讨

本研究根据国家原卫生部、中医药管理局医药机构文件管理的相关规定,结合我国医院药剂科药事管理的现状,分析药剂科药事管理在医院管理工作中的实质、目的、存在的问题及解决对策,运用成熟的管理学知识,说明药事管理的重要性。我国应该推行医药分家,优化管理制度,采用信息化、现代化的方式对药品进行管理,加快推进临床药学工作的发展,从而推动医院的建设和发展,为人民的健康谋福祉。     

人-机-环境系统工程中航空卫生保障工作是重要环节（摘要）

高性能战斗机是一个复杂的人-机-环境系统,航卫保障对保持和提高飞行员能力素质具有重要意义。在空军的军事训练中,需要加强专业训练措施,进一步密切人一机结合。因此,建议抓紧建立新的航空卫生保障内容标准体系并完善航空卫生的保障体制。     

64-row multi-dector computed tomography coronary image from a center with early experience: first illustration of learning curve

Background and objectives The recent joint ACCF/AHA clinical competence statement on cardiac imaging with multi-detector computed tomography recommended a minimum of 6 months training and 300 contrast examinations, of which the candidate must be directly involved in at least 100 studies. Whether this is adequate to become proficient in interpretation of coronary computed tomography angiography (CTA) is not known. The aim of our study was to plot the 'learning curve' for CTA assessment of haemodynamically significant coronary stenosis in a center with 1 year's experience using a 64-row scanner. Methods A total of 778 patients underwent contrast-enhanced CTA between January and December 2005. Out of these patients, 301 patients also underwent contrast-enhanced conventional coronary angiography (CCA). These patients were divided into 4 groups according to the time the examination was underwent. Group Q1: first quarter of the year (n=20), Group Q2: second quarter (n=128), Group Q3: third quarter ( n=134), and Group Q4: fourth quarter ( n=19). For Group Q4 patients we used a 'test-bolus' protocol instead of 'bolus-tracking' for contrast-enhancement. Results The sensitivity, specificity, positive, and negative predictive values were Ql - 64%, 89%, 49% and 94%, respectively; Q2 -79%, 96%, 74% and 97%, respectively; Q3 - 78%, 96%, 74%, 97%, respectively, and Q4 - 100% for all. Conclusions In a center with formal training and high caseload, our accuracy in CTA analysis reached a plateau after 6 months experience. Test-bolus protocols produce better image quality and can improve accuracy. New centers embarking on CTA will need to overcome an initial 6-month learning curve depending upon the caseload during which time they should consider correlation with CCA. (J Geriatr Cardiol 2006; 3(1):29-34)     

乳腺癌改良根治术后应用带蒂背阔肌皮瓣移植一期乳房再造

目的：介绍应用带蒂背阔肌皮瓣移植进行乳腺癌改良根治术后一期乳房再造的方法与疗效。方法：自2000年，用带蒂背阔肌皮瓣移植方法对中青年妇女乳腺癌改良根治术后行一期乳房再造20例。结果：全部病例的肌皮瓣及其中4例同时保留乳头病例的乳头均存活，无积液、感染、坏死等并发症，再造乳房外形美观。结论：用带蒂背阔肌皮瓣移植行乳腺癌术后一期乳房再造是乳腺癌改良根治术后恢复乳房外形的一种理想方法。     

帕金森病模型大鼠黑质多巴胺能神经元的氧化应激研究

目的　探索帕金森病模型大鼠黑质多巴胺能神经元的氧化应激发病机制。方法　通过立体定位仪 ,将 6-OHDA注入大鼠一侧纹状体内制备 PD模型 ,2周后观察动物的行为学改变 ,2个月后观察黑质纹状体等的病理形态学变化 ,检测模型组、假手术组和正常对照组的超氧化物歧化酶 (SOD)的活性 ,丙二醛 (MDA)、一氧化氮(NO)代谢产物 (NO x)的含量的变化。结果　成功 PD模型鼠有 2 2只。光镜下 HE染色示模型组右侧黑质的多巴胺神经元受损 ,数目减少。模型组右侧黑质的 SOD的含量下降 ,MDA及 NO x含量明显升高 ,与左侧、假手术组及正常对照组相比有显著差异 (P>0 .0 5)。结论　 6-OHDA纹状体内双靶点注射法是一种有效的制备 PD模型的方法。帕金森病大鼠模型黑质内 SOD活性下降 ,MDA、NO x含量升高 ,氧化应激在 PD的发病中起重要的作用     

镉诱导小鼠胸腺细胞凋亡的研究

目的 探索镉的免疫毒性机制,系统性地研究镉体外诱导小鼠胸腺细胞凋亡的发生,解释其细胞毒性机制。方法 通过以下方法检测凋亡;末端脱氧核苷酸转移酶介导的dUTP缺口末端标记（TUNEL）,DNA含量/细胞周期分析,DNA琼脂糖凝胶电泳。结果 镉能引起原代培养的胸腺细胞发生凋亡,并呈时间-反应和剂量-效应关系。结论 本研究为阐述镉免疫毒性机制提供了依据,尤其对解释镉引起的胸腺萎缩和导致的T细胞介导的免疫力损伤有重要意义。