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41.
Yuki Okamoto Kazuo Yamamoto Tsutomu Sugimoto Fuyuki Asami Ayako Nagasawa Satoru Shiraiwa Norihito Nakamura Shinpei Yoshii 《Heart and vessels》2014,29(6):864-866
We encountered a surgical case of middle aortic syndrome (MAS) in a 56-year-old man who had resistant hypertension. Computed tomography showed severe stenosis of the abdominal aorta from below the superior mesenteric artery to above the inferior mesenteric artery. Although bilateral renal artery stenosis was confirmed, renal function was within normal limits. A 10-mm vascular prosthetic graft was used to perform a descending aorta to left external iliac artery bypass. His hypertension was well controlled without medication. This extra-anatomic bypass may be a simple and useful approach for treating MAS if it is not necessary to reconstruct the renal artery or visceral artery. 相似文献
42.
Tomoko Miki Osamu Yokota Takashi Haraguchi Hideki Ishizu Masato Hasegawa Takeshi Ishihara Shu‐ichi Ueno Shintaro Takenoshita Seishi Terada Norihito Yamada 《Brain pathology (Zurich, Switzerland)》2020,30(4):811-830
Granular/fuzzy astrocytes (GFAs), a subtype of “aging‐related tau astrogliopathy,” are noted in cases bearing various neurodegenerative diseases. However, the pathogenic significance of GFAs remains unclear. We immunohistochemically examined the frontal cortex, caudate nucleus, putamen and amygdala in 105 cases composed of argyrophilic grain disease cases (AGD, N = 26), and progressive supranuclear palsy (PSP, N = 10), Alzheimer’s disease (AD, N = 20) and primary age‐related tauopathy cases (PART, N = 18) lacking AGD, as well as 31 cases bearing other various neurodegenerative diseases to clarify (i) the distribution patterns of GFAs in AGD, and PSP, AD and PART lacking AGD, (ii) the impacts of major pathological factors and age on GFA formation and (iii) immunohistochemical features useful to understand the formation process of GFAs. In AGD cases, GFAs consistently occurred in the amygdala (100%), followed by the putamen (69.2%) and caudate nucleus and frontal cortex (57.7%, respectively). In PSP cases without AGD, GFAs were almost consistently noted in all regions examined (90–100%). In AD cases without AGD, GFAs were less frequent, developing preferably in the putamen (35.0%) and caudate nucleus (30.0%). PART cases without AGD had GFAs most frequently in the amygdala (35.3%), being more similar to AGD than to AD cases. Ordered logistic regression analyses using all cases demonstrated that the strongest independent factor of GFA formation in the frontal cortex and striatum was the diagnosis of PSP, while that in the amygdala was AGD. The age was not significantly associated with GFA formation in any region. In GFAs in AGD cases, phosphorylation and conformational change of tau, Gallyas‐positive glial threads indistinguishable from those in tufted astrocytes, and the activation of autophagy occurred sequentially. Given these findings, AGD, PSP, AD and PART cases may show distinct distributions of GFAs, which may provide clues to predict the underlying processes of primary tauopathies. 相似文献
43.
Incidence of Urolithiasis in Northeast Thailand 总被引:3,自引:0,他引:3
Makoto Yanagawa Juichi Kawamura Takehisa Onishi Norihito Soga Koji Kameda Pote Sriboonlue Vitoon Prasongwattana Sombat Borwornpadungkitti 《International journal of urology》1997,4(6):537-540
Background :
Urolithiasis is a major health problem in the northeast part of Thailand. In this study, we examined the prevalence of renal stone disease and differences of urinary components between stone formers and healthy control subjects in northeastern rural areas of Thailand.
Methods :
We selected 3 villages in the rural areas of Khon Kaen province in northeast Thailand. Three hundred and sixty-seven persons were asked questions relating to urolithiasis and were examined by abdominal ultrasound (US). We collected a spot urine sample from stone formers and healthy control subjects from each village.
Results :
Abnormal findings by US were detected in 39 individuals (10.6%), and included 31 individuals with renal calculi (8.4%), 16 with hydronephrosis (4.4%), and 1 individual with a renal cyst (0.3%). This yielded a disease rate of urinary stones in this study of 16.9%. The male/female ratio was 2/1 and the average age of the individuals examined was 40.3 + 13.9 years. However, there was no significant difference between the urinary parameters of stone formers and the healthy control subjects. Conclusion: There was a high incidence of renal stone disease in the northeast part of Thailand, but the tendency for hypocitraturia was only found in stone formers. 相似文献
Urolithiasis is a major health problem in the northeast part of Thailand. In this study, we examined the prevalence of renal stone disease and differences of urinary components between stone formers and healthy control subjects in northeastern rural areas of Thailand.
Methods :
We selected 3 villages in the rural areas of Khon Kaen province in northeast Thailand. Three hundred and sixty-seven persons were asked questions relating to urolithiasis and were examined by abdominal ultrasound (US). We collected a spot urine sample from stone formers and healthy control subjects from each village.
Results :
Abnormal findings by US were detected in 39 individuals (10.6%), and included 31 individuals with renal calculi (8.4%), 16 with hydronephrosis (4.4%), and 1 individual with a renal cyst (0.3%). This yielded a disease rate of urinary stones in this study of 16.9%. The male/female ratio was 2/1 and the average age of the individuals examined was 40.3 + 13.9 years. However, there was no significant difference between the urinary parameters of stone formers and the healthy control subjects. Conclusion: There was a high incidence of renal stone disease in the northeast part of Thailand, but the tendency for hypocitraturia was only found in stone formers. 相似文献
44.
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46.
Small Bowel Perforation Caused by Metastasis from an Extra-Abdominal Malignancy: Report of Three Cases 总被引:2,自引:0,他引:2
Small bowel perforation is rarely caused by metastasis from an extra-abdominal malignancy. This report describes three cases
of small bowel perforation that occurred secondary to a metastatic tumor. The first case involved a 72-year-old man with malignant
lymphoma of the larynx that had been treated with chemo- and radiation therapy; the second involved a 70-year-old man with
rhabdomyosarcoma of the mediastinum that had been treated with radiation therapy; and the third involved a 41-year-old man
with lung carcinoma that had been treated with surgery 10 months prior to perforation. Each patient presented with acute abdominal
pain, had X-ray findings of free air in the abdomen, and underwent limited emergency surgery. Wedge resection and closure
of the ileum was performed for the first patient and partial bowel resection with the creation of an intestinal stoma was
performed for the second and third patients. In each case, the histologic findings of the resected specimens were consistent
with the extra-abdominal primary tumors. Although the patients recovered sufficiently to begin eating and moving about, all
three died of cancer or cancer-related complications within 45 days of surgery. We conclude that surgeons should be aware
of the poor prognosis of such patients and perform only the minimal surgery required.
Received: April 7, 2000 / Accepted: September 26, 2000 相似文献
47.
Satoshi Ida MD PhD Masaru Morita MD PhD FACS Yukiharu Hiyoshi MD PhD Keisuke Ikeda MD Koji Ando MD PhD Yasue Kimura MD PhD Hiroshi Saeki MD PhD Eiji Oki MD PhD Tetsuya Kusumoto MD PhD Sei Yoshida MD PhD Torahiko Nakashima MD PhD Masayuki Watanabe MD PhD FACS Hideo Baba MD PhD FACS Yoshihiko Maehara MD PhD FACS 《Annals of surgical oncology》2014,21(4):1175-1181
Background
Cancer of the hypopharynx and cervical esophagus (PhCe cancer) frequently develops synchronously or metachronously with esophageal cancer. The surgical approach is usually difficult, especially in metachronous PhCe cancer after esophagectomy. The purpose of this study was to clarify the treatment outcomes of patients with metachronous PhCe cancer with a history of esophagectomy.Methods
The subjects evaluated in this study were 14 patients with metachronous PhCe cancer who underwent pharyngo-laryngo-esophagectomy after subtotal esophagectomy and gastric tube pull-up for primary esophageal cancer.Results
Definitive chemoradiotherapy (CRT; radiation dose >50 Gy) was performed for primary laryngeal (n = 1), pharyngeal (n = 2), esophageal (n = 1), and recurrent esophageal cancer (n = 2). For seven patients with metachronous PhCe cancer, induction CRT (radiation dose <40 Gy) was performed. In all 14 patients, pharyngo-laryngo-esophagectomy was followed by free jejunal graft interposition with reconstruction of the jejunal vessels. Although postoperative complications developed in four patients, no perioperative death or necrosis of the reconstructed free jejunum occurred. The 2- and 5-year overall survival rates were 84 and 50 %, respectively.Conclusions
Pharyngo-laryngo-esophagectomy with free jejunal transfer is considered to be safe for metachronous PhCe cancer, even in patients with a history of CRT and esophagectomy. 相似文献48.
Kumiko Nakao Yuka Shimonagano Norihito Doi Taiji Sakamoto 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2007,245(9):1383-1386
Background To report on conjunctival nodules as an unusual manifestation of Vogt-Koyanagi-Harada disease.
Methods A 24-year-old woman presented with a two-month history of bilateral conjunctival injection and gradually decreased vision.
Ophthalmological examinations revealed bilateral granulomatous uveitis and bulbar conjunctival nodules, and a biopsy of the
conjunctival nodules was performed.
Results The biopsy specimens showed noncaseating granulomas. The major components of the infiltrating lymphocytes were CD8-positive
T cells. Topical corticosteroid therapy reduced the anterior segment inflammation, and the conjunctival nodules disappeared
within a week. Afterwards, the patient demonstrated bilateral retinal detachments, sunset glow fundus and alopecia, and, therefore,
was diagnosed to have Vogt-Koyanagi-Harada disease four months after the first symptoms.
Conclusions Conjunctival nodules may represent the primary manifestation of Vogt-Koyanagi-Harada disease.
Financial disclosure: none. 相似文献
49.
Yu Imamura Yoshifumi Baba Shinji Ishikawa Yukiharu Hiyoshi Youhei Nagai Tadahiko Nakamura Naoko Hayashi Nobutomo Miyanari Kenichi Iyama Hideo Baba 《Gastric cancer》2008,11(4):219-225
Background The muscularis propria of the stomach is histologically divided into three layers; namely, the innermost oblique, the inner
circular, and the outer longitudinal layers. In patients with gastric cancer the depth of tumor invasion has been reported
to correlate with lymph node metastasis and prognosis. However, it is unclear whether the depth of tumor invasion in the muscularis
propria has an effect on lymph node metastasis and prognosis.
Methods Fifty-nine gastric cancer patients with muscularis propria invasion were analyzed retrospectively. These patients were divided
into two groups, the inner group, with invasion up to the inner circular layer; and the outer group, with invasion beyond
the inner circular layer. The relationships between tumor invasion and clinicopathological factors and survival were evaluated.
Results Of the 59 patients, 34 were classified as the inner group, and 25 were classified as the outer group. The inner group had
a significantly lower probability of lymph node metastasis (P = 0.0053) and a significantly better overall cancer-specific survival (P = 0.017) than the outer group.
Conclusion Gastric cancers with muscularis propria invasion had heterogeneous prognoses according to the tumor depth in the muscularis
propria layers. 相似文献
50.