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排序方式: 共有759条查询结果,搜索用时 46 毫秒
741.
Antonella Gallo Noemi Macerola Angela Maria Favuzzi Maria Anna Nicolazzi Antonio Gasbarrini Massimo Montalto 《Medical principles and practice》2022,31(3):203
Heart failure (HF) represents a major health problem affecting millions of people worldwide. In the latest years, many efforts have been made to search for more effective strategies to prevent and modify the course of this disease, but results are still not satisfying. HF represents a complex clinical syndrome involving many other systems, including the gastrointestinal system. Although the relationship between the gut and HF is far from being fully understood, based on recent evidence highlighting the putative role of the gastrointestinal system in different cardiovascular diseases, it is conceivable that the gut-heart link may represent the basis for novel therapeutic approaches in the HF context as well. This intricate interplay involving typical hemodynamic changes and their consequences on gut morphology, permeability, and function, sets the stage for alterations in microbiota composition and is able to impact mechanisms of HF through different routes such as bacterial translocation and metabolic pathways. Thus, the modulation of the gut microbiota through diet, probiotics, and fecal transplantation has been suggested as a potential therapeutic approach. More interestingly, another effect of alteration in microbiota composition reflects in the upregulation of cotransporters (NHE3) with consequent salt and fluid overload and worsening visceral congestion. Therefore, the inhibitors of this cotransporter may also represent a novel therapeutic frontier. By review of recent data on this topic, we describe the current state of the complex interplay between the gastrointestinal and cardiac systems in HF, and the relevance of this knowledge in seeking new therapeutic strategies. 相似文献
742.
Giulia Collatuzzo Vittorio Lodi Daniela Feola Giuseppe De Palma Emanuele Sansone Emma Sala Christian Janke Noemi Castelletti Stefano Porru Gianluca Spiteri Maria Grazia Lourdes Monaco Francesca Larese Filon Corrado Negro Luca Cegolon Jana Beresova Eleonora Fabianova Lucia A. Carrasco-Ribelles Pere Torn-Monserrat Marta Maria Rodriguez-Suarez Guillermo Fernandez-Tardon Shuffield S. Asafo Giorgia Ditano Mahsa Abedini Paolo Boffetta 《Viruses》2022,14(12)
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745.
Francesco Cavallieri Annalisa Gessani Andrea Merlo Isabella Campanini Carla Budriesi Valentina Fioravanti Giulia Di Rauso Alberto Feletti Benedetta Damiano Sara Scaltriti Noemi Guagnano Elisa Bardi Maria Giulia Corni Francesca Antonelli Francesca Cavalleri Maria Angela Molinari Sara Contardi Elisa Menozzi Annette Puzzolante Giuseppe Vannozzi Elena Bergamini Giacomo Pavesi Valérie Fraix Sara Meoni Alessandro Fraternali Annibale Versari Mirco Lusuardi Giuseppe Biagini Serge Pinto Elena Moro Franco Valzania 《European journal of neurology》2023,30(7):1963-1972
746.
Olga Gorlanova Heide Oller Andrea Marten Loretta Müller Jessica Laine-Carmelli Fabienne Decrue Yasmin Salem Danielle Vienneau Kees de Hoogh Amanda Gisler Jakob Usemann Insa Korten Sophie Yammine Uri Nahum Noemi Künstle Pablo Sinues Sven Schulzke Philipp Latzin Oliver Fuchs Martin Röösli Bianca Schaub Urs Frey the BILD study group 《Pediatric allergy and immunology》2023,34(1):e13902
747.
Kavita Krell Albert Pless Jr Carie Michael Amy Torres Jeanhee Chung Sandra Baker Jasmine M. Blake Kelli Caughman Sarah Cullen Maureen Gallagher Roxanne Hoke-Chandler Julius Maina Diana McLuckie Kate O'Neill Angeles Peña Dina Royal Michelle Slape Noemi Alice Spinazzi Carlos G. Torres Brian G. Skotko 《American journal of medical genetics. Part A》2023,191(3):742-752
Scant research has explored the healthcare experiences of people with Down syndrome (DS) in the United States who are Black, African American, of African descent, or of mixed race. The purpose of this study was to identify and describe the barriers and facilitators that such patients and their caregivers face when accessing healthcare. We gathered data in three ways: focus groups with caregivers, a national survey completed by caregivers, and in-depth interviews with primary care providers. Many caregivers and primary care physicians felt that patients with DS who are Black, African American, of African descent, or of mixed race receive a lower quality of medical care than their white counterparts with DS. Caregivers mentioned feeling tired of being reminded by the medical community about their race and wanting acknowledgment that raising a child with DS can be hard at times. Many felt that the medical community's conscious and unconscious racial biases do negatively impact the care of their loved ones with DS. Caregivers desired more race concordant medical providers or, when not possible, medical providers who are willing to learn more about DS and build trusted, longitudinal relationships. Primary care providers discussed the need for funded resources and support services to effectively care for their patients with DS. 相似文献
748.
Sara Dionisi RN MSc PhD Adoración Muñoz-Alonso RN MSc Noemi Giannetta RN MSc PhD Alejandra Aranburu-Imatz RN MSc Pablo J. López-Soto RN MSc PhD Pedro A. Galey-Chica RN MSc Francisco Escribano-Villanueva RN MSc Aurora De Leo RN MSc PhDs Gloria Liquori RN MSc PhDs Marco Di Muzio RN MSc PhD Emanuele Di Simone RN MSc PhD 《Public health nursing (Boston, Mass.)》2023,40(6):817-825
749.
Roberta Bovenzi Giulia Maria Sancesario Matteo Conti Piergiorgio Grillo Rocco Cerroni Jacopo Bissacco Paolo Forti Emilia Giannella Massimo Pieri Silvia Minosse Valentina Ferrazzoli Noemi Pucci Mario Laudazi Roberto Floris Francesco Garaci Mariangela Pierantozzi Alessandro Stefani Nicola Biagio Mercuri Eliseo Picchi Francesca Di Giuliano Tommaso Schirinzi 《European journal of neurology》2023,30(7):1983-1990
750.
Francesco Paolo Bianchi Pasquale Stefanizzi Donato Rizzi Noemi Signorile Eustachio Cuscianna Antonio Daleno Giovanni Migliore Silvio Tafuri 《British journal of haematology》2023,201(6):1072-1080
Splenectomy/asplenia is a condition associated with immune-compromission and specific vaccines are recommended for these patients, including the anti-COVID-19 vaccine. Among the high-risk group for which vaccination was prioritized in Italy, the immunocompromised patients after therapies or treatments were included. The Apulian regional archive of hospital discharge forms was used to define the list of splenectomized Apulian inhabitants, considering data from 2015 through 2020. The overall vaccination status of asplenic patients was assessed via data collected from the Regional Immunization Database. The history of SARS-CoV-2 infection and the infectious disease outcomes were extracted from the Italian Institute of Health platform “Integrated surveillance of COVID-19 cases in Italy”. 1219 Apulian splenectomized inhabitants were included; the incidence rate of SARS-CoV-2 infection was 15.0 per 100 persons-year with a proportion of re-infection equal to 6.4%; the proportion of hospitalization was 2.9%, with a case-fatality rate of 2.6%. The vaccine coverage (VC) for the anti-COVID-19 vaccine basal routine was 64.2%, for the first booster dose was 15.4%, and for the second booster dose was 0.6%. A multifactorial approach is needed to increase the vaccination uptake in this sub-group population and to increase the awareness of the asplenia-related risks to patients and health personnel. 相似文献