全文获取类型
收费全文 | 2869篇 |
免费 | 138篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 18篇 |
妇产科学 | 47篇 |
基础医学 | 319篇 |
口腔科学 | 112篇 |
临床医学 | 170篇 |
内科学 | 712篇 |
皮肤病学 | 50篇 |
神经病学 | 235篇 |
特种医学 | 144篇 |
外科学 | 422篇 |
综合类 | 4篇 |
预防医学 | 183篇 |
眼科学 | 116篇 |
药学 | 202篇 |
中国医学 | 6篇 |
肿瘤学 | 269篇 |
出版年
2023年 | 11篇 |
2022年 | 23篇 |
2021年 | 42篇 |
2020年 | 28篇 |
2019年 | 31篇 |
2018年 | 42篇 |
2017年 | 25篇 |
2016年 | 41篇 |
2015年 | 39篇 |
2014年 | 61篇 |
2013年 | 84篇 |
2012年 | 132篇 |
2011年 | 161篇 |
2010年 | 103篇 |
2009年 | 81篇 |
2008年 | 110篇 |
2007年 | 108篇 |
2006年 | 135篇 |
2005年 | 164篇 |
2004年 | 168篇 |
2003年 | 143篇 |
2002年 | 130篇 |
2001年 | 118篇 |
2000年 | 107篇 |
1999年 | 104篇 |
1998年 | 26篇 |
1997年 | 23篇 |
1996年 | 30篇 |
1995年 | 25篇 |
1994年 | 22篇 |
1993年 | 22篇 |
1992年 | 57篇 |
1991年 | 50篇 |
1990年 | 49篇 |
1989年 | 58篇 |
1988年 | 61篇 |
1987年 | 45篇 |
1986年 | 43篇 |
1985年 | 50篇 |
1984年 | 39篇 |
1983年 | 28篇 |
1982年 | 17篇 |
1979年 | 27篇 |
1978年 | 18篇 |
1977年 | 22篇 |
1976年 | 8篇 |
1975年 | 12篇 |
1974年 | 17篇 |
1973年 | 10篇 |
1969年 | 12篇 |
排序方式: 共有3015条查询结果,搜索用时 656 毫秒
91.
Radical scavenging activity of carbon nanotubes: toward appropriate selection of a radical initiator
Radical scavenging activities are attractive properties not only for scientific fields e.g. biomedicine, but for the materials industry. In this study, we report that carbon nanotubes (CNTs) can scavenge radicals from organic peroxides, while radicals from azo-type radical initiators exhibit only a few effects from the presence of CNTs. In addition, experimental results suggest the possibility that captured peroxide radicals generate active radical sites on the CNT surface, from which polymerization can take place. These results indicate the importance of selecting an appropriate radical initiator.Carbon nanotubes scavenge radicals preferentially from peroxides, and polymerization presumably takes place from generated active radical sites on the surface. 相似文献
92.
Hiromi Tateno MD PhD Ryuji Sakakibara MD PhD Shunsuke Shiina BSci Hirokazu Doi PhD Fuyuki Tateno MD PhD Mitsutoshi Sato PhD Tohru Masaka PhD Masahiko Kishi MD PhD Yohei Tsuyusaki MD Yosuke Aiba MD Tsuyoshi Ogata MSc Yasuo Suzuki MD PhD 《Journal of the American Geriatrics Society》2015,63(11):2416-2418
93.
Akiko Kishi Svensson Mariusz Kitlinski Peter Almgren Gunnar Engström Peter M. Nilsson Olle Melander 《Diabetologia》2018,61(2):331-341
Aims/hypothesis
Sleep duration is a risk factor for incident diabetes mellitus and CHD. The primary aim of the present study was to investigate, in sex-specific analyses, the role of incident diabetes as the possible biological mechanism for the reported association between short/long sleep duration and incident CHD. Considering that diabetes is a major risk factor for CHD, we hypothesised that any association with sleep duration would not hold for cases of incident CHD occurring before incident diabetes (‘non-diabetes CHD’) but would hold true for cases of incident CHD following incident diabetes (‘diabetes-CHD’).Methods
A total of 6966 men and 9378 women aged 45–73 years from the Malmö Diet Cancer Study, a population-based, prospective cohort, who had answered questions on habitual sleep duration and did not have a history of prevalent diabetes or CHD were included in the analyses. Incident cases of diabetes and CHD were identified using national registers. Sex-specific Cox proportional hazards regression models were stratified by BMI and adjusted for known covariates of diabetes and CHD.Results
Mean follow-up times for incident diabetes (n = 1137/1016 [men/women]), incident CHD (n = 1170/578), non-diabetes CHD (n = 1016/501) and diabetes-CHD (n = 154/77) were 14.2–15.2 years for men, and 15.8–16.5 years for women. In men, short sleep duration (< 6 h) was associated with incident diabetes (HR 1.35, 95% CI 1.01, 1.80), CHD (HR 1.41, 95% CI 1.06, 1.89) and diabetes-CHD (HR 2.34, 95% CI 1.20, 4.55). Short sleep duration was not associated with incident non-diabetes CHD (HR 1.35, 95% CI 0.98, 1.87). Long sleep duration (≥ 9 h) was associated with incident diabetes (HR 1.37, 95% CI 1.03, 1.83), CHD (HR 1.33, 95% CI 1.01, 1.75) and diabetes-CHD (HR 2.10, 95% CI 1.11, 4.00). Long sleep duration was not associated with incident non-diabetes CHD (HR 1.33, 95% CI 0.98, 1.80). In women, short sleep duration was associated with incident diabetes (HR 1.53, 95% CI 1.16, 2.01), CHD (HR 1.46, 95% CI 1.03, 2.07) and diabetes-CHD (HR 2.88, 95% CI 1.37, 6.08). Short sleep duration was not associated with incident non-diabetes CHD (HR 1.29, 95% CI 0.86, 1.93).Conclusions/interpretation
The associations between sleep duration and incident CHD directly reflect the associations between sleep duration and incident diabetes. Incident diabetes may thus be the explanatory mechanism for the association between short and long sleep duration and incident CHD.94.
Insulin production in a neuroectodermal tumor that expresses islet factor-1, but not pancreatic-duodenal homeobox 1 总被引:4,自引:0,他引:4
95.
Subacute cor pulmonale due to tumor embolism 总被引:1,自引:0,他引:1
Nakamura H Adachi H Sudoh A Yagyu H Kishi K Oh-ishi S Kusama H Hashimoto T Matsuoka T 《Internal medicine (Tokyo, Japan)》2004,43(5):420-422
We describe a patient wih subacute cor pulmonale caused by tumor emboli in the lungs. A 64-year-old female suffering from a subacute progressive cough and shortness of breathing died of severe pulmonary hypertension seven days after admission. Neither chest CT scans nor lung perfusion scintigraphy showed any abnormal findings. Microscopic examination after an autopsy revealed diffuse intravascular tumor emboli occluding not only the small pulmonary arteries and arterioles, but also the lymphatic vessels, which were suggested to be metastases of a breast carcinoma resected five years previously. Thus, pulmonary tumor embolism should be considered in the differential diagnosis of primary pulmonary hypertension, particularly in patients with a past history of cancers. 相似文献
96.
97.
Ryosuke Sakemi Suketo So Yosuke Morimitsu Hajime Imada Hiroshi Ishihara Kenjiro Kuhara Yuichiro Oku Hiroya Terabe Masahiro Kishi Ei Sasaki Miyuki Sakemi Masayuki Shimokobe 《Clinical journal of gastroenterology》2014,7(4):310-315
Primary squamous cell carcinoma is rarely observed, with a reported incidence of 0.04–0.07 % of all gastric cancers. An 81-year-old male underwent chemoradiotherapy for type 1 gastric cancer of the posterior wall of the cardiac region in 2005. The tumor disappeared after 1 year of therapy, following which an area of white epithelium, approximately 30 mm in diameter and continuous with the esophageal mucosa, became visible. Biopsy of the white epithelium indicated normal squamous epithelium. An elevated lesion was subsequently detected in the area of white epithelium on upper gastrointestinal endoscopy during a follow-up examination 5 years after therapy. As a biopsy of the same site indicated squamous cell carcinoma, we performed endoscopic submucosal dissection. Histopathological examination indicated high-grade fibrosis due to radiotherapy and showed a moderately differentiated squamous cell carcinoma invading the scarred portion. We describe a case where the developmental process of a squamous cell carcinoma was observed using endoscopy, including narrow band imaging with magnification. This carcinoma likely originated from squamous metaplasia that developed after chemoradiotherapy was administered for a gastric cancer. 相似文献
98.
99.
100.