全文获取类型
收费全文 | 1896篇 |
免费 | 66篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 74篇 |
儿科学 | 147篇 |
妇产科学 | 54篇 |
基础医学 | 130篇 |
口腔科学 | 101篇 |
临床医学 | 146篇 |
内科学 | 382篇 |
皮肤病学 | 41篇 |
神经病学 | 99篇 |
特种医学 | 75篇 |
外科学 | 451篇 |
综合类 | 27篇 |
预防医学 | 56篇 |
眼科学 | 35篇 |
药学 | 93篇 |
中国医学 | 9篇 |
肿瘤学 | 58篇 |
出版年
2023年 | 3篇 |
2022年 | 19篇 |
2021年 | 19篇 |
2020年 | 28篇 |
2019年 | 36篇 |
2018年 | 24篇 |
2017年 | 31篇 |
2016年 | 35篇 |
2015年 | 42篇 |
2014年 | 45篇 |
2013年 | 70篇 |
2012年 | 111篇 |
2011年 | 97篇 |
2010年 | 58篇 |
2009年 | 70篇 |
2008年 | 150篇 |
2007年 | 168篇 |
2006年 | 148篇 |
2005年 | 167篇 |
2004年 | 150篇 |
2003年 | 127篇 |
2002年 | 100篇 |
2001年 | 45篇 |
2000年 | 43篇 |
1999年 | 31篇 |
1998年 | 3篇 |
1997年 | 3篇 |
1996年 | 3篇 |
1994年 | 5篇 |
1993年 | 6篇 |
1992年 | 13篇 |
1991年 | 20篇 |
1990年 | 12篇 |
1989年 | 7篇 |
1988年 | 6篇 |
1987年 | 3篇 |
1986年 | 9篇 |
1985年 | 14篇 |
1984年 | 8篇 |
1981年 | 3篇 |
1980年 | 3篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1974年 | 2篇 |
1973年 | 6篇 |
1972年 | 7篇 |
1971年 | 2篇 |
1970年 | 4篇 |
1968年 | 3篇 |
1966年 | 2篇 |
排序方式: 共有1978条查询结果,搜索用时 15 毫秒
61.
Alkan A Inal S Baş B Ozer M 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(6):e5-e11
Maxillary distraction osteogenesis has become an accepted alternative method in the treatment of patients with severe maxillary hypoplasia in craniofacial syndromes and cleft-related deformities. Insufficient distraction, undesirable soft tissue changes, and occurrence of defective distraction vectors are among the potential complications of intraoral maxillary distraction osteogenesis. A 2-stage procedure combining maxillary advancement by distraction technique with genioplasty and mandibular setback surgery was planned to correct jaw deformities in a 22-year-old patient with severe maxillary retrusion, mandibular prognathism, and excessive lower facial height. In the first stage, osteotomies were performed and maxilla was lightly mobilized after down-fracture. Distractors were placed to the maxilla intraorally. During activation period, the maxilla rotated in a clockwise direction, producing a discrepancy between the planned and the actual vectors. Complete distraction was unsatisfactory and the complication was due to surgical technique. This case report presents the failure of maxillary distraction due to incomplete mobilization of the maxilla. Treatment of the case was achieved by the conventional osteotomy techniques at final operation. The maxilla was successfully advanced to the desired position producing good occlusion and an improved facial profile. 相似文献
62.
Dundar Tolga Turan Abdallah Anas Yurtsever Ismail Guler Eray Metin Ozer Omer Faruk Uysal Omer 《Neurosurgical review》2020,43(6):1595-1603
Neurosurgical Review - Neuroinflammation plays an important role in neuronal injury after aneurysmal subarachnoid hemorrhage (aSAH). Sulfonylurea receptor 1 (SUR1) and transient receptor potential... 相似文献
63.
International Urology and Nephrology - To evaluate the effects of aging on the success rate of retrograde intrarenal surgery (RIRS) and the development of medical and surgical complications by... 相似文献
64.
Seyma Ozer Kaya Fatih Mehmet Kandemir Seyfettin Gur Mine Erisir Fulya Benzer Emre Kaya Gaffari Turk Mustafa Sonmez 《Andrologia》2020,52(1):e13439
The purpose of this study is to investigate the effects of L-arginine on spermatological parameters, seminal plasma nitric oxide levels and arginase enzyme activities. Fertile rams that are 2–3 years old and weighing 50–60 kg were used as material. The semen was collected by artificial vagina at 1st, 4th, 24th, 48th, 72nd, 96th and 120th hours for the control group before L-arginine administration. For treatment groups, L-arginine was administered intraperitoneally at a dose of 5 mg kg−1 bw−1 and semen was collected at the time point described for the control group. Spermatological characteristics of semen samples (semen volume, pH, sperm motility, concentration and abnormal sperm rate), seminal plasma nitric oxide levels and arginase enzyme activities were determined. Increased seminal plasma nitric oxide level (p < .01), seminal plasma arginase activity (p < .01), semen volume (p < .05), semen mass activity (p < .05), sperm motility (p < .05) and concentration (p < .01) and decreased abnormal sperm rate (p < .05 and p < .01) were observed by L-arginine administration. In conclusion, it may be concluded that L-arginine application in rams during the breeding season may have positive effects on rams' reproductive performance. 相似文献
65.
66.
Clinicopathologic predictors of recurrence and overall survival in adenoid cystic carcinoma of the head and neck: A single institutional experience at a tertiary care center
下载免费PDF全文
![点击此处可从《Head & neck》网站下载免费的PDF全文](/ch/ext_images/free.gif)
67.
68.
Kagansky N Levy S Rimon E Cojocaru L Fridman A Ozer Z Knobler H 《Archives of internal medicine》2003,163(15):1825-1829
BACKGROUND: Hypoglycemia during hospitalization occurs in patients with and without diabetes. The aims of this study were to determine the incidence, associated risk factors, and short- and long-term outcome of hypoglycemia among hospitalized elderly patients. METHODS: This is a case-control study conducted at geriatric and medicine departments. All patients 70 years or older with documented hypoglycemia hospitalized within 1 year (n = 281) were compared with a nonhypoglycemic group of 281 elderly, randomly selected patients from the same hospitalized population. RESULTS: Among 5404 patients 70 years or older, 281 (5.2%) had documented hypoglycemia. Compared with the nonhypoglycemic group, we found the following characteristics to be true in the hypoglycemic group: there were more women than men (58% vs 44%, P =.001); sepsis was 10 times more common (P<.001); malignancy was 2.8 times more common (P =.04); the mean serum albumin level was lower (2.8 g/dL vs 3.4 g/dL, P<.001); and the mean serum creatinine and alkaline phosphatase levels were higher (P<.001 for both). Diabetes was known in 42% of the hypoglycemic group and in 31% of the nonhypoglycemic group (P =.03); 70 patients in the hypoglycemic group were taking sulfonylureas or insulin. Multivariate logistic analysis showed that sepsis, albumin level, malignancy, sulfonyurea and insulin treatment, alkaline phosphatase level, female sex, and creatinine level were all independent predictors of developing hypoglycemia. In-hospital mortality and 3-month mortality were about twice as high in the hypoglycemic group (P<.001). Multivariate analysis of mortality found that sepsis, low albumin level, and malignancy were independent predictors, while hypoglycmia was not. CONCLUSIONS: Hypoglycemia was common in elderly hospitalized patients and predicted increased in-hospital 3- and 6-month cumulative mortality. However, in a multivariate analysis, hypoglycemia was not an independent predictor for mortality, implying that it is only a marker. 相似文献
69.
Peru H Soylemezoglu O Gonen S Cetinyurek A Bakkaloğlu SA Buyan N Hasanoglu E 《Clinical rheumatology》2008,27(1):5-10
Henoch Schonlein purpura (HSP) is the most common vasculitis of childhood. Susceptibility to HSP and associated clinical heterogeneity
in HSP may be conferred by a number of genetic loci, including the major histocompatibility complex. We aimed to investigate
the implications of the human leukocyte antigen (HLA) class 1 alleles in susceptibility to HSP and determine the possible
associations with renal, gastrointestinal (GI), and joint manifestations of the disease. 110 children with HSP (66 boys, 44
girls) and 250 unrelated healthy controls were enrolled in the study. The mean age was 8.65 ± 3.59 years. HSP was diagnosed
on the basis of clinical and laboratory data according to the American College of Rheumatology classification. The diagnosis
was supported with skin and/or kidney in most of the patients. Clinical and laboratory findings revealed: skin involvement
in 110 (100%), joint manifestations in 82 (74.5%), GI symptoms in 58 (52.7%), and hematuria and/or proteinuria in 36 (32.7%)
patients. HLA class 1 alleles were identified by DNA amplification, hybridized with specific primer sequences. Comparison
of frequencies between patients and controls were made by using the Fisher’s exact test. Odds ratio (OR) was used as the measure
of association. HLA A2, A11, and B35 antigens showed an increased risk for predisposition to HSP (OR = 1.714, 95%CI = 1.088–2.700,
p = 0.020; OR = 2.185, 95%CI = 1.289–3.703, p = 0.003; and OR = 2.292, 95%CI = 1.451–3.619, p = 0.000, respectively), while HLA A1, B49, and B50 antigens revealed decreased risk for predisposition to HSP (OR = 4.739,
95%CI = 1.828–12.345, p = 0.001; OR = 3.268, 95%CI = 0.955–11.236, p = 0.047; and OR = 7.462, 95%CI = 0.975–55.555, p = 0.024, respectively). Considering the renal involvement and severity of proteinuria, there was no association with HLA
class 1 alleles. Our results suggest that the increased frequency of HLA A2, A11, and B35 alleles in unselected pediatric
HSP patient population and miscarrying of HLA A1, B49, and B50 could be considered as a risk factor for susceptibility to
HSP. 相似文献
70.
Serum positive cagA in patients with non-ulcer dyspepsia and peptic ulcer disease from two centers in different regions of Turkey 总被引:1,自引:0,他引:1
Serin E Yilmaz U Künefeci G Ozer B Gümürdülü Y Güçlü M Kayaselçuk F Boyacioğlu S 《World journal of gastroenterology : WJG》2003,9(4):833-835
AIM: To investigate and compare frequencies of serum positive cagA in patients from two separate regions of Turkey who were grouped according to the presence of peptic ulcer disease or non-ulcer dyspepsia. METHODS: One hundred and eighty Helicobacter pylori-positive patients with peptic ulcer disease or non-ulcer dyspepsia were included in the study. One hundred and fourteen patients had non-ulcer dyspepsia and 66 had peptic ulcer disease (32 with gastric ulcers and/or erosions and 34 with duodenal ulcers). Each patient was tested for serum antibody to H. pylori cagA protein by enzyme immunoassay. RESULTS: The total frequency of serum positive cagA in the study group was 97.2 %. The rates in the patients with peptic ulcers and in those with non-ulcer dyspepsia were 100 % and 95.6 %, respectively. These results were similar to those reported in Asian studies, but higher than those that have been noted in other studies from Turkey and Western countries. CONCLUSION: The high rates of serum positive cagA in these patients with peptic ulcer disease and non-ulcer dyspepsia were similar to results reported in Asia. The fact that there was high seroum prevalence regardless of ulcer status suggests that factors other than cagA might be responsible for ulceration or other types of severe pathology in H. pylori-positive individuals. 相似文献