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排序方式: 共有3829条查询结果,搜索用时 15 毫秒
61.
62.
Aniel J. L. Brambila-Tapia Jorge I. G��mez-Nava Laura Gonz��lez-L��pez Lucila Sandoval-Ram��rez Julio Med��na-D��az Montserrat Maldonado Sergio R. Gutierrez-Ure?a Gloria Mart��nez-Bonilla Beatriz T. Mart��n-M��rquez M��nica V��zquez del Mercado Arnulfo Nava-Zavala Jos�� F. Mu?oz-Valle Mario Salazar-P��ramo Ingrid P. D��valos-Rodr��guez 《Rheumatology international》2011,31(8):1065-1068
The objective of this study is to establish whether there is an association between the presence of FCGR3A V(176) polymorphism with SLE or its manifestations. We included 94 patients according to the 1982 ACR criteria as well as 98 controls matched by age and gender. The 11 ACR diagnostic criteria were analyzed on the clinical files. The polymorphism FCGR3A V(176) was determined by direct sequencing. There was not an association between the polymorphism FCGR3A V(176) with SLE or its main manifestations. The allelic frequency for F(176) was: 0.80 and 0.72 in cases and controls, respectively (P?=?0.09, IC95%: 0.42?C1.07); and the genotypic frequency in the group of cases was: 0.65 for homozygotes F(176)/F(176), 0.30 for heterozygotes and 0.05 for the homozygotes V(176)/V(176), while for the control group it was 0.53, 0.39 and 0.08, respectively. The polymorphism FCGR3A V(176) is not associated with SLE or any of its manifestations in patients with SLE from the West of Mexico. 相似文献
63.
Antonio Moreno Galdó Juan Solé Montserrat Antonio Roman Broto 《Archivos de bronconeumologia》2013,49(12):523-528
Lung transplantation has become in recent years a therapeutic option for infants with terminal lung disease with similar results to transplantation in adults. In Spain, since 1996 114 children lung transplants have been performed; this corresponds to 3.9% of the total transplant number. The most common indication in children is cystic fibrosis, which represents between 70-80% of the transplants performed in adolescents. In infants common indications are interstitial lung disease and pulmonary hypertension. In most children a sequential double lung transplant is performed, generally with the help of extracorpo-real circulation. Lung transplantation in children presents special challenges in monitoring and follow-up, especially in infants, given the difficulty in assessing lung function and performing transbronchial biopsies.There are some more specific complications in children like postransplant lymphoproliferative syndrome or a greater severity of respiratory virus infections. After lung transplantation children usually experiment a very important improvement in their quality of life. Eighty eight per cent of children have no limitations in their activity after 3 years of transplantation. According to the registry of the International Society for Heart & Lung Transplantation (ISHLT) survival at 5 years of transplantation is 54% and at 10 years is around 35%. 相似文献
64.
Feliciano Villar Montserrat Celdran Josep Fabà 《Gerontology & geriatrics education》2014,35(2):171-181
The goals of this study were to determine the learning impact of an assignment that consisted of interviewing and analyzing older people’s life stories, and to explore how the assignment was evaluated by students. Participants in the study were 122 first-year social education students enrolled in an adult development and aging course. They evaluated the assignment using an eight-adjective questionnaire and were asked about the benefits of the task. Their answers to the questionnaire were then reviewed using content analysis. The results indicated that marks on the life story assignment predicted marks on an exam about basic course concepts. Students considered that the assignment was interesting, useful, and integrated into the course, although most of them also thought that it was very time-consuming. They identified benefits related to the explicit goals of the course (improvement in the learning of developmental concepts, the acquisition of research-related skills, and the deactivation of aging stereotypes) and personal, growth-related benefits. The authors discuss the difficulties posed by the assignment and its usefulness as a complement to more traditional, lecture-based teaching methods in adult development and aging courses. 相似文献
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67.
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease in
which most patients die of respiratory failure. Although volume-targeted non-invasive
bilevel positive airway pressure (BPAP) ventilation has been studied in patients with
chronic respiratory failure of various etiologies, its use in ALS has not been
reported. We present the case of a 66-year-old woman with ALS and respiratory failure
treated with volume-targeted BPAP ventilation for 15 weeks. Weekly data downloads
showed that disease progression was associated with increased respiratory muscle
weakness, decreased spontaneous breathing, and increased use of non-invasive positive
pressure ventilation, whereas tidal volume and minute ventilation remained relatively
constant. 相似文献
68.
José Sanz-Santos Mireia Martínez-Palau Àngels Jaen Ramón Rami-Porta Bienvenido Barreiro Sergi Call Carme Obiols José Manuel González José Ángel De Marcos Montserrat Ysamat Lydia Canales Mireia Serra Josep Belda 《The Annals of thoracic surgery》2021,111(4):1190-1197
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69.
Carme Ferré-Grau María Sevilla-Casado Montserrat Boqué-Cavallé M. Rosa Aparicio-Casals Amparo Valdivieso-López Mar Lleixá-Fortuño 《Atencion primaria / Sociedad Espa?ola de Medicina de Familia y Comunitaria》2012,44(12):695-701
ObjectiveTo determine the effectiveness of Problem Solving Technique in reducing anxiety and depression, and increased perceived well-being in women family caregivers of chronic patients.DesignA clinical trialField of studyHealth centres in Tarragona, Spain, during 2007-2011.ParticipantsA sample 122 caregivers of patients in home care programs that met the inclusion criteria, were assigned to intervention or control group according to a simple random process.InterventionsIn the experimental group, the nurses applied the Problem Solving Technique to the caregiver according to a four-session protocol. The nurses provided the usual care to the caregivers In the control group. One month after intervention, the dependent vriables were measured again in both groups.Principal measurementThe dependent variables of anxiety and depression were measured using the Goldberg scale, and the emotional well-being variable by the scale of emotional health of the primary caregiver.ResultsA statistically significant improvement was detected in the anxiety and depression symptoms, as well as the perceived well-being in the intervention group compared to the control group.ConclusionsImplementation of the Problem Solving Technique is a useful therapeutic tool for reducing symptoms of distress in family caregivers of chronic patients. 相似文献
70.
Susanne Halken Desiree Larenas‐Linnemann Graham Roberts Moises A. Calderón Elisabeth Angier Oliver Pfaar Dermot Ryan Ioana Agache Ignacio J. Ansotegui Stefania Arasi George Du Toit Montserrat Fernandez‐Rivas Roy Geerth van Wijk Marek Jutel Jörg Kleine‐Tebbe Susanne Lau Paolo M. Matricardi Giovanni B. Pajno Nikolaos G. Papadopoulos Martin Penagos Alexandra F. Santos Gunter J. Sturm Frans Timmermans R. van Ree Eva‐Maria Varga Ulrich Wahn Maria Kristiansen Sangeeta Dhami Aziz Sheikh Antonella Muraro 《Pediatric allergy and immunology》2017,28(8):728-745
Allergic diseases are common and frequently coexist. Allergen immunotherapy (AIT) is a disease‐modifying treatment for IgE‐mediated allergic disease with effects beyond cessation of AIT that may include important preventive effects. The European Academy of Allergy and Clinical Immunology (EAACI) has developed a clinical practice guideline to provide evidence‐based recommendations for AIT for the prevention of (i) development of allergic comorbidities in those with established allergic diseases, (ii) development of first allergic condition, and (iii) allergic sensitization. This guideline has been developed using the Appraisal of Guidelines for Research & Evaluation (AGREE II) framework, which involved a multidisciplinary expert working group, a systematic review of the underpinning evidence, and external peer‐review of draft recommendations. Our key recommendation is that a 3‐year course of subcutaneous or sublingual AIT can be recommended for children and adolescents with moderate‐to‐severe allergic rhinitis (AR) triggered by grass/birch pollen allergy to prevent asthma for up to 2 years post‐AIT in addition to its sustained effect on AR symptoms and medication. Some trial data even suggest a preventive effect on asthma symptoms and medication more than 2 years post‐AIT. We need more evidence concerning AIT for prevention in individuals with AR triggered by house dust mites or other allergens and for the prevention of allergic sensitization, the first allergic disease, or for the prevention of allergic comorbidities in those with other allergic conditions. Evidence for the preventive potential of AIT as disease‐modifying treatment exists but there is an urgent need for more high‐quality clinical trials. 相似文献