经内镜结扎及硬化联合治疗食管静脉曲张出血的探讨

食管静脉曲张破裂出血是肝硬化门静脉高压症常见的并发症,内镜食管静脉硬化（ＥＶＳ）和内镜食管静脉结扎术（ＥＶＬ）治疗食管静脉曲张出血（ＥＶＢ）,国内外已公认其止血效果,并列为首选治疗方法,但各有优缺点［１］。单纯多次ＥＶＳ治疗具有局部和全身并发症,止血...     

Effect of Structure and Hydrogen on the Short-Term Creep of Titanium Ti-2.9Al-4.5V-4.8Mo Alloy

In this paper, the effect of hydrogenation, in the amount of 0.15 wt.%, on the short-term creep of a titanium Ti-2.9Al-4.5V-4.8Mo alloy in fine-grained (FG) and ultrafine-grained (UFG) states is studied at 723 K. The UFG structure was formed by the method of pressing with the change of the deformation axis and gradual temperature decrease. Creep tests are performed under conditions of uniaxial tension at a constant load for the creep rates at an interval of (10⁻⁷ ÷ 10⁻⁶) s⁻¹. The UFG alloy’s resistance to creep under the investigated conditions is revealed to be substantially lower than in the FG state. When hydrogen presents in the alloy in a solid solution, a 1.3–2.5-fold rise in the value of the steady-state creep rate for the hydrogenated FG and UFG alloys is observed. The creep of the non-hydrogenated FG and UFG alloys is described by the creep power law. The presence of dissolved hydrogen leads to a violation of the creep power law. The values of stress sensitivity indices, steady-state creep rate, and effective creep activation energy are determined. The relationships between the hydrogenation, structure, and creep mechanisms of the alloy at the steady-state are discussed.     

Development of an experimental multichannel equipment complex for controlling bioelectric processes in the stomach and intestines

The multichannel informative set of devices provides high-fidelity recording of bioelectric potentials from the human anterior abdominal wall to examine the activity of the stomach and the small and large intestine.     

Computerized hydrodynamic ″flow″ system for artificial heart valve testing

Scientific-Research Institute of Transplantation and Artificial Organs, Ministry of Health of the USSR, Moscow. Translated from Meditsinskaya Tekhnika, No. 6, pp. 30–32, November–December, 1990.     

Aneuploidy and percentage of S-phase cells determined by flow cytometry correlate with cell phenotype in childhood acute leukemia

Cellular DNA content distributions of propidium-iodide-stained bone marrow blasts were determined by flow cytometry (FCM) for 225 untreated children with acute leukemia and were correlated with leukemia cell phenotype and karyotype. Aneuploidy of the primary malignant stem line was detected in 54 cases (24%): 51 hyperdiploid and 3 hypodiploid. A second stem line with approximately twice the DNA content of the primary stem line was recognized by FCM in 28 cases (23 ALL, 5 ANLL) and may be an important source of leukemia cell heterogeneity. The degree of DNA content abnormality detected by FCM was highly correlated (r = 0.98) with the number of whole chromosome gains or losses in the leukemia karyotype. Aneuploidy detectable by FCM was more frequent in acute lymphoblastic leukemia (ALL) (52 of 173, 30.1%) than in acute nonlymphoblastic leukemia (2 of 52, 3.8%) (p less than 0.001). In the ALL group, aneuploidy was significantly correlated with the cell surface expression of common ALL antigen: 46 of 127 antigen-positive cases were aneuploid compared to 6 of 46 antigen-negative cases (p less than 0.003). Only 2 of 21 cases of T-cell ALL without common ALL antigen had detectable aneuploidy, which was significantly less than in the common ALL group (p = 0.02). The median percentage of cells in S- phase was significantly greater for B-cell and erythrocyte rosette- positive T-cell ALL, than for the other phenotypic subgroups. We conclude that aneuploidy and S-phase cell percentage are correlated with the state of leukemia cell differentiation. The biologic basis for the correlation is not established, but may be linked to the process of malignant transformation.     

Polychemotherapy using platidiam in disseminated squamous cell cancer of the head and neck

The report discusses the effectiveness of chemotherapy in 60 patients with advanced squamous cell carcinoma of the head and neck (platidiam + prospidin-40; platidiam + cyclophosphamide and bleomycin-20). The latter procedure proved slightly more effective.