全文获取类型
收费全文 | 41032篇 |
免费 | 3820篇 |
国内免费 | 85篇 |
专业分类
耳鼻咽喉 | 507篇 |
儿科学 | 1480篇 |
妇产科学 | 1150篇 |
基础医学 | 5502篇 |
口腔科学 | 842篇 |
临床医学 | 5621篇 |
内科学 | 7775篇 |
皮肤病学 | 546篇 |
神经病学 | 3222篇 |
特种医学 | 1082篇 |
外科学 | 5108篇 |
综合类 | 691篇 |
一般理论 | 67篇 |
预防医学 | 4881篇 |
眼科学 | 684篇 |
药学 | 2868篇 |
1篇 | |
中国医学 | 116篇 |
肿瘤学 | 2794篇 |
出版年
2023年 | 326篇 |
2022年 | 503篇 |
2021年 | 1101篇 |
2020年 | 682篇 |
2019年 | 1065篇 |
2018年 | 1195篇 |
2017年 | 904篇 |
2016年 | 908篇 |
2015年 | 1020篇 |
2014年 | 1431篇 |
2013年 | 1956篇 |
2012年 | 2867篇 |
2011年 | 2880篇 |
2010年 | 1548篇 |
2009年 | 1255篇 |
2008年 | 2296篇 |
2007年 | 2380篇 |
2006年 | 2175篇 |
2005年 | 2163篇 |
2004年 | 1908篇 |
2003年 | 1730篇 |
2002年 | 1551篇 |
2001年 | 760篇 |
2000年 | 664篇 |
1999年 | 694篇 |
1998年 | 383篇 |
1997年 | 357篇 |
1996年 | 314篇 |
1995年 | 250篇 |
1994年 | 228篇 |
1993年 | 203篇 |
1992年 | 485篇 |
1991年 | 465篇 |
1990年 | 418篇 |
1989年 | 387篇 |
1988年 | 388篇 |
1987年 | 367篇 |
1986年 | 371篇 |
1985年 | 372篇 |
1984年 | 282篇 |
1983年 | 253篇 |
1982年 | 183篇 |
1981年 | 183篇 |
1979年 | 258篇 |
1978年 | 211篇 |
1977年 | 182篇 |
1974年 | 194篇 |
1973年 | 213篇 |
1972年 | 169篇 |
1971年 | 162篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
41.
Michelle L. DeOliveira Timothy M. Pawlik Ana L. Gleisner Lia Assumpcaom Gaspar J. Lopes-Filho Michael A. Choti 《Journal of gastrointestinal surgery》2007,11(8):970-976
Survival after resection of colorectal liver metastases has traditionally been associated with clinicopathologic factors.
We sought to investigate whether echogenicity of colorectal liver metastasis as assessed by intraoperative ultrasound (IOUS)
was a prognostic factor after hepatic resection. Prospective data on tumor IOUS appearance were collected in 84 patients who
underwent hepatic resection for colorectal liver metastasis. Images were digitally recorded, blindly reviewed, and scored
for echogenicity (hypo-, iso-, or hyperechoic). The median tumor number was 1 and the median tumor size was 5.0 cm. At the
time of surgery, the IOUS appearance of the colorectal liver metastases were hypoechoic in 35 (41.7%) patients, isoechoic
in 37 (44.0%) patients, and hyperechoic in 12 (14.3%) patients. Traditional clinicopathologic prognostic factors were similarly
distributed among the three echogenicity groups (all p > 0.05). Patients with a hypoechoic lesion had a significantly shorter median survival (30.2 months) compared with patients
who had either an isoechoic (53.2 months) or hyperechoic (42.3 months) lesion (p = 0.005). The 5-year survival after hepatic resection of colorectal liver metastasis was also associated with the echogenic
appearance of the lesion (hypoechoic 14.4 vs isoechoic 37.4 vs hyperechoic 46.2%) (p < 0.05). Intraoperative ultrasound echogenicity should be considered a prognostic factor after hepatic resection of metastatic
colorectal cancer.
This study was presented at the 47th annual meeting of The Society for Surgery of the Alimentary Tract, Los Angeles, CA, USA,
22 May 2006. 相似文献
42.
Steven Z George John D Childs Deydre S Teyhen Samuel S Wu Alison C Wright Jessica L Dugan Michael E Robinson 《BMC musculoskeletal disorders》2007,8(1):92
Background
There are few effective strategies reported for the primary prevention of low back pain (LBP). Core stabilization exercises targeting the deep abdominal and trunk musculature and psychosocial education programs addressing patient beliefs and coping styles represent the current best evidence for secondary prevention of low back pain. However, these programs have not been widely tested to determine if they are effective at preventing the primary onset and/or severity of LBP. The purpose of this cluster randomized clinical trial is to determine if a combined core stabilization exercise and education program is effective in preventing the onset and/or severity of LBP. The effect of the combined program will be compared to three other standard programs. 相似文献43.
It's all about sex: gender, lung development and lung disease. 总被引:1,自引:0,他引:1
Michelle A Carey Jeffrey W Card James W Voltz Samuel J Arbes Dori R Germolec Kenneth S Korach Darryl C Zeldin 《Trends in Endocrinology and Metabolism》2007,18(8):308-313
Accumulating evidence suggests that gender affects the incidence, susceptibility and severity of several lung diseases. Gender also influences lung development and physiology. Data from both human and animal studies indicate that sex hormones might contribute to disease pathogenesis or serve as protective factors, depending on the disease involved. In this review, the influence of gender and sex hormones on lung development and pathology will be discussed, with specific emphasis on pulmonary fibrosis, asthma and cancer. 相似文献
44.
Michael D. Lara M.D. Matthew T. Baker M.D. Christopher J. Larson PA-C R.D. Michelle A. Mathiason M.S. Pamela J. Lambert R.N. Shanu N. Kothari M.D. 《Surgery for obesity and related diseases》2005,1(1):597-21
BACKGROUND: There is no consensus regarding the optimal rate of follow-up in the post-bariatric surgery patient population. METHODS: The records of all patients who underwent laparoscopic Roux-en-Y gastric bypass from 2001 to 2003 were reviewed. Using patient zip codes, travel distances were calculated between the patients' places of residence and our clinic. Patients were then assigned to 1 of 3 cohorts according to the following distances: (1) < 50 miles, (2) 50 to 100 miles, and (3) > 100 miles. Patient compliance with follow-up appointments at 3 weeks, 3 months, 6 months, 9 months, and 12 months was analyzed. Linear trends were identified using the Mantel-Haenszel test. Age and sex were analyzed as possible predictors of compliance using the chi(2) test. P values < .05 were considered statistically significant. RESULTS: The study group comprised 150 patients (127 females and 23 males). The 3 cohorts contained 115, 21, and 14 patients, respectively. All patients in each cohort were compliant with the 3-week follow-up appointment. Although there were differences in compliance between cohorts at each of the remaining appointments, only the 9-month (70.3% vs 61.9% vs 35.7%) visit showed statistical significance (P = .035). The 6-month visit trended toward significance (85.2% vs 76.2% vs 64.3%; P = .088). Males were more likely to be compliant with the 12-month follow-up (P = .040). When controlling for sex, travel distance was also a predictor of compliance at this follow-up visit (P = .024). Age was not predictive of compliance (P = .827). CONCLUSION: Based on our findings, we conclude that travel distance from the clinic does not significantly affect compliance at the initial follow-up, 3-month, and 12-month appointments. However, distance does tend to affect compliance at the 6-month appointment and significantly affects compliance at the 9-month appointment. Males are more likely to be compliant at the 12 month follow-up visit. We must continue to strive for 100% follow-up in our post-bariatric surgery patients. 相似文献
45.
46.
BACKGROUND: The reconstruction of small defects of the alar groove can be a unique challenge owing to the importance of maintaining its concave structure. OBJECTIVE: To present a report of a patient with a small alar groove defect that was repaired using a combination of partial primary closure and second-intention healing. METHODS: A 73-year-old female was referred for the treatment of a basal cell carcinoma of the right nasal ala and underwent Mohs micrographic surgery with clearance of the lesion. The final defect, less than 1 cm, extended to the subcutaneous fat. Two absorbable subcutaneous sutures were placed in the defect, and the wound was then allowed to heal by second intention. RESULTS. This closure yielded a good cosmetic result, with preservation of the alar groove. CONCLUSION: A combination of primary closure and second-intention healing is a time-efficient, low-risk option for nonperforating, small alar groove defects. 相似文献
47.
48.
L. C. Scott G. K. Wright G. S. Rai A. N. Exton-Smith J. M. Gardiner 《International journal of geriatric psychiatry》1991,6(8):583-588
Memory performance of elderly patients in the early stages of Alzheimer's disease (DAT) was compared with that of elderly control subjects. In explicit tests of recognition memory, which involve conscious recollection, the DAT patients were grossly impaired. In implicit tests of anagram solution and wordstem completion, which do not require conscious recollection, the DAT patients were not impaired. These findings further support the idea that a separate memory system, episodic memory, underlies conscious recollection, that it is this system which is most commonly damaged in amnesia, and that memory systems not involving conscious recollection may be spared in the early stages of Alzheimer's disease. 相似文献
49.
We report a case of multiple endocrine neoplasia type I and hypernephroma. Parathyroid hyperplasia, adrenocortical hyperplasia, a nodular goiter, multiple lipomas, a chromophobe adenoma of the pituitary and hypernephroma had all been diagnosed previously. All but the last are features consistent with the diagnosis of multiple endocrine neoplasia type I (Wermer's syndrome). The association of multiple endocrine neoplasia type I and hypernephroma may represent a new manifestation of this pleiotropic syndrome. 相似文献
50.
Intervention studies aimed at promoting increased physical activity have been trialled in many different settings including primary care, worksites and the community. Churches are also potential settings for physical activity promotion. However, little is known about the effectiveness of this setting for promoting physical activity, particularly in Australia. The purpose of this study was to evaluate the effectiveness of a mind, body and spiritually based health promotion program in increasing physical activity and promoting mental and spiritual health. Nineteen women completed the 8-week intervention, and 30 women in a non-health related 8-week program at the same church comprised a comparison group. Pre- and post-program surveys assessed outcome measures. Between-group differences over time were examined using one-way MANOVA's. Physical activity was higher in the intervention group than the comparison group. In contrast to the comparison group, both mental health (depression symptoms) and spiritual health improved significantly more among intervention participants. The data highlight the potential for a church-based setting and holistic approach to health promotion as a successful means of increasing physical activity and promoting mental and spiritual health among Australian women. 相似文献