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Histiocytic sarcoma (true histiocytic lymphoma): a clinicopathological study of 20 cases 总被引:1,自引:0,他引:1
P. VAN DER VALK C.J. L.M. MEIJER R. WILLEMZE A.T. VAN OOSTEROM† P.J. SPAANDER‡ J. TE VELDE 《Histopathology》1984,8(1):105-123
Large-cell non-Hodgkin's lymphomas (T- and B-immunoblastic, centroblastic and true histiocytic lymphomas) have a heterogeneous clinical course. In the present study the clinical and morphological data of 20 cases of histiocytic sarcoma (true histiocytic lymphoma) are presented. Diagnosis was supported by immunohistochemistry, cytochemistry, rosette assays and/or electron microscopy. Although the follow-up was relatively short (up to 144 months, mean 26 months), the clinical data differed clearly from the series of large-cell non-Hodgkin lymphomas, recorded in the literature. Differences were found in age distribution with a peak in the third decade, in organ involvement showing a preference for skin, gastrointestinal tract and bone, and in response to therapy. In general, histiocytic sarcoma appears to have a more favourable response to therapy and clinical course than the other large-cell lymphomas (T- and B-immunoblastic and centroblastic lymphomas). Moreover, preliminary observations in the group of histiocytic sarcomas suggested that the presence of lysozyme and/or 5-nucleotidase and the absence of alpha 1-antitrypsin in the cytoplasm is associated with a better response to therapy and favourable clinical course. 相似文献
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TE Wiswell 《Acta paediatrica (Oslo, Norway : 1992)》2001,90(S436):28-30
Meconium aspiration syndrome (MAS) is a common cause of respiratory distress in neonates. In many affected children, the complex nature of meconium aspiration syndrome contributes to the apparent lack of response to standard therapies. Over the past decade, several new therapies have been suggested to be more effective than "conventional" management in treating meconium aspiration syndrome. These include: anti-inflammatory drugs, medications to counter the effect of prostaglandin-related compounds, high-frequency ventilation, exogenous surfactant, inhaled nitric oxide and liquid ventilation. There are, however, scant evidence-based data to justify routine use of any of those therapies. Additional prospective, well-controlled, randomized trials of diverse therapies are needed to elucidate the optimum management of MAS. 相似文献
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Influence of Genotype on Structural Atrial Abnormalities and Atrial Fibrillation or Flutter in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
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MIMOUNT BOURFISS B.S. ANNELINE S.J.M. TE RIELE M.D. Ph.D. THOMAS P. MAST M.D. MAARTEN J. CRAMER M.D. Ph.D. JEROEN F. VAN DER HEIJDEN M.D. Ph.D. TOON A.B. VAN VEEN Ph.D. PETER LOH M.D. Ph.D. DENNIS DOOIJES Ph.D. RICHARD N.W. HAUER M.D. Ph.D. BIRGITTA K. VELTHUIS M.D. Ph.D. 《Journal of cardiovascular electrophysiology》2016,27(12):1420-1428
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TV Mulaudzi JV Robbs N Paruk B Pillay TE Madiba V Govindsamy 《Cardiovascular journal of Africa》2009,20(3):170-172