全文获取类型
收费全文 | 34769篇 |
免费 | 2961篇 |
国内免费 | 1467篇 |
专业分类
耳鼻咽喉 | 546篇 |
儿科学 | 657篇 |
妇产科学 | 593篇 |
基础医学 | 4198篇 |
口腔科学 | 619篇 |
临床医学 | 3650篇 |
内科学 | 5776篇 |
皮肤病学 | 799篇 |
神经病学 | 2260篇 |
特种医学 | 1104篇 |
外国民族医学 | 13篇 |
外科学 | 4365篇 |
综合类 | 4530篇 |
现状与发展 | 6篇 |
一般理论 | 21篇 |
预防医学 | 2130篇 |
眼科学 | 1192篇 |
药学 | 2838篇 |
19篇 | |
中国医学 | 1210篇 |
肿瘤学 | 2671篇 |
出版年
2024年 | 69篇 |
2023年 | 452篇 |
2022年 | 1021篇 |
2021年 | 1500篇 |
2020年 | 1106篇 |
2019年 | 1042篇 |
2018年 | 1151篇 |
2017年 | 1038篇 |
2016年 | 1028篇 |
2015年 | 1390篇 |
2014年 | 1702篇 |
2013年 | 1641篇 |
2012年 | 2514篇 |
2011年 | 2536篇 |
2010年 | 1525篇 |
2009年 | 1254篇 |
2008年 | 1798篇 |
2007年 | 1871篇 |
2006年 | 1811篇 |
2005年 | 1783篇 |
2004年 | 1296篇 |
2003年 | 1132篇 |
2002年 | 1034篇 |
2001年 | 851篇 |
2000年 | 863篇 |
1999年 | 824篇 |
1998年 | 456篇 |
1997年 | 391篇 |
1996年 | 292篇 |
1995年 | 313篇 |
1994年 | 255篇 |
1993年 | 187篇 |
1992年 | 338篇 |
1991年 | 304篇 |
1990年 | 297篇 |
1989年 | 272篇 |
1988年 | 227篇 |
1987年 | 224篇 |
1986年 | 205篇 |
1985年 | 157篇 |
1984年 | 110篇 |
1983年 | 82篇 |
1981年 | 57篇 |
1979年 | 77篇 |
1978年 | 54篇 |
1977年 | 55篇 |
1976年 | 50篇 |
1974年 | 67篇 |
1973年 | 64篇 |
1972年 | 70篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
141.
142.
目的:血清中IL-6和IL-8的含量是临床检验中的重要指标,本实验主要对肝癌患者血清的IL-6和IL-8的水平进行了统计分析,为进一步临床监测提供依据。方法:对86份肝癌患者血清进行检测,同时收集30份正常血清和35份肝硬化患者血清作为对照比较。结果:肝癌患者血清中IL-6水平[(0.197±0.041)ng/ml]显著高于对照组(正常组的0.159±0.038;肝硬化组0.185±0.026);肝癌患者血清中IL-8水平[(0.463±0.127)ng/ml],显著高于对照组(正常组的0.354±0.113;肝硬化组,0.386±0.102)。结论:血清中IL-6、IL-8水平可以作为肝癌的临床监测指标。 相似文献
143.
Hisashi Sugiyama Toshie Kadono Minako Hoshiai Tetsushi Tan Keiichi Koizumi Hajime Sakamoto Simpei Nakazawa 《Catheterization and cardiovascular interventions》2004,63(3):346-350
We report here the first described case of utilizing gadolinium-based contrast material as the contrast agent during a catheter intervention treatment for pulmonary artery stenosis. The patient, a male infant with complex heart disease associated with a right isomerism, had a history of severe allergic reaction to iodine-containing contrast agents. A combination of digital subtraction angiography and a gadolinium contrast agent, however, provided us with good-quality images both before and after balloon angioplasty without any associated complications. This method should therefore be considered as an alternative angiographic procedure in children with a high risk of iodine-related allergic complications. 相似文献
144.
目的探讨颈椎不稳症的影像学诊断。方法回顾性分析50例经临床证实的颈椎不稳症患者的X线平片、CT和MRI检查资料。结果50例中上颈椎不稳16例,其中,寰枕关节不稳2例,表现为枕底—齿突线和斜坡—齿突线不连续,14例为寰枢关节不稳,其中,寰枢关节脱位7例;下颈椎不稳34例,其中,前屈不稳20例,后伸不稳14例。结论X线平片、CT和MRI综合分析能对颈椎不稳症作出准确的诊断。 相似文献
145.
Objective:To evaluate the feasibility and safety of prenatal diagnosis by traneabdominal chorionic villus sam-pling(TA-CVS)via the guidance of B-mode ultrasound in the first trimester of gestation.To explore the technique of long time culture and chromosome preparation of villi in early pregnancy.To evaluate the feasibility of the above techniques in the application of the prenatal cytogenetic diagnosis.Methods:One hundred and thirty-five singleton pregnancies at risk were referred from January 2001 to Decem-ber 2007.Results:The average maternal age was 35.2 years.TA-CVS was performed in the 10~13th weeks of gestation and the average gestational age was 10.89 weeks.All attempts at sampling were successful.The rate of operation-associated fetal loss was 0.74%.The failure rate of prenatal diagnosis because of inadequate amount of specimen was 0.The average culture time was 5-7 days.The success rate of the cell culture was 98.5%.No maternal con-temination and bacterial contamination happened.Fifteen cases of abnormal karyotype and one case of confined pla-cantel mosaiciem were diagnosed.Conclusion:TA-CVS appears to be safe and feasible and might to be offered in the prenatal diagnosis in the first trimester of gestation.The technique of long time culture and chromosome preparation of villi is stable and reliable.It is feasible to apply these techniques in the clinical practice of prenatal cytogenetic diagnose in the early pregnancy. 相似文献
146.
Yasushi Nishihira Chun‐Feng Tan Junko Hirato Junichi Yoshimura Kenichi Nishiyama Hideaki Takahashi Yukihiko Fujii Hitoshi Takahashi 《Neuropathology》2007,27(6):551-555
Two embryonal CNS tumors, atypical teratoid/rabdoid tumor (AT/RT) and primitive neuroectodermal tumor (PNET), may be confused with each other and misdiagnosed. Here we report an infant with a congenital supratentorial tumor, which was detected by fetal MRI at 37 weeks gestation. On routine histological examination, the tumor was composed mainly of small undifferentiated cells, among which many rhabdoid cells and occasional sickle‐shaped embracing cells were observed. No mesenchymal or epithelial areas were evident. Our impression was that the tumor was an atypical example of AT/RT. Immunohistochemically, almost all the tumor cells were strongly positive for vimentin. However, epithelial membrane antigen was notably negative, and most of the tumor cell nuclei were clearly positive for INI1. In addition, many tumor cells were positive for neurofilament protein. There were also occasional small areas containing many tumor cells positive for glial fibrillary acidic protein. Finally, a diagnosis of PNET, with a rhabdoid phenotype and expression of neuronal and glial markers, was made. In the present case, application of INI1 immunostaining was very helpful for distinguishing PNET from AT/RT. 相似文献
147.
148.
149.
Motor imagery (MI), which refers to the process of mental representation of movements, has not been studied in patients with essential tremor (ET). We investigated the presence of impaired MI in ET patients compared with healthy controls. A group of drug-naive and nondemented ET patients and age-matched controls were studied using transcranial magnetic stimulation, while they were specifically instructed to try and imagine themselves performing two motor tasks. The various clinical and electrophysiological variables were evaluated and compared. Repeated measures ANOVA demonstrated a significant difference between ET patients and controls with respect to mean motor-evoked potential (MEP) amplitudes (F(1,38) = 31.92, P < 0.005) during MI. The process of MI effectively facilitated MEP amplitude in controls but not in ET patients, regardless of side of stimulation or motor tasks. We provide evidence to demonstrate impairment of MI in a group of ET patients compared with healthy controls. The basis for this novel finding is unclear, and further studies are warranted to determine whether it is related to cerebellar or motor cortical dysfunction. 相似文献
150.
椎管内占位病变的CT评价 总被引:4,自引:0,他引:4
本文回顾性分析了28例椎管内占位病变(包括椎管内肿瘤24例、蛛网膜囊肿2例、硬膜外脓肿和椎同盘突出各1例)的CT表现。着重讨论了造影剂增强CT的特征。大多数增强CT可显示肿块的轮廓,有助于肿块定位。室管膜瘤和星形细胞瘤的增强CT表现类似,但雪旺氏瘤、海绵状血管瘤和脓肿具有增强CT特征;同时还对脂肪瘤、脊膜瘤和蛛网膜囊肿的增强CT特征进行了探讨。增强CT定位困难时,CTM可有很大的帮助。 相似文献