全文获取类型
收费全文 | 846篇 |
免费 | 85篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 4篇 |
儿科学 | 66篇 |
妇产科学 | 10篇 |
基础医学 | 116篇 |
口腔科学 | 33篇 |
临床医学 | 101篇 |
内科学 | 164篇 |
皮肤病学 | 19篇 |
神经病学 | 30篇 |
特种医学 | 128篇 |
外科学 | 119篇 |
综合类 | 43篇 |
预防医学 | 28篇 |
眼科学 | 29篇 |
药学 | 22篇 |
肿瘤学 | 27篇 |
出版年
2022年 | 2篇 |
2021年 | 4篇 |
2020年 | 7篇 |
2019年 | 7篇 |
2018年 | 19篇 |
2017年 | 7篇 |
2016年 | 21篇 |
2015年 | 22篇 |
2014年 | 26篇 |
2013年 | 44篇 |
2012年 | 21篇 |
2011年 | 16篇 |
2010年 | 45篇 |
2009年 | 48篇 |
2008年 | 20篇 |
2007年 | 33篇 |
2006年 | 21篇 |
2005年 | 25篇 |
2004年 | 16篇 |
2003年 | 20篇 |
2002年 | 18篇 |
2001年 | 15篇 |
2000年 | 12篇 |
1999年 | 11篇 |
1998年 | 47篇 |
1997年 | 46篇 |
1996年 | 44篇 |
1995年 | 40篇 |
1994年 | 23篇 |
1993年 | 31篇 |
1992年 | 13篇 |
1991年 | 10篇 |
1990年 | 8篇 |
1989年 | 20篇 |
1988年 | 20篇 |
1987年 | 19篇 |
1986年 | 17篇 |
1985年 | 22篇 |
1984年 | 15篇 |
1983年 | 18篇 |
1982年 | 9篇 |
1981年 | 15篇 |
1980年 | 8篇 |
1979年 | 4篇 |
1978年 | 7篇 |
1977年 | 9篇 |
1976年 | 9篇 |
1975年 | 2篇 |
1973年 | 1篇 |
1884年 | 1篇 |
排序方式: 共有939条查询结果,搜索用时 15 毫秒
91.
Anne-Cathrine Mattiasson PhD RNT Lars Andersson PhD 《Journal of advanced nursing》1997,26(6):1117-1124
Interviews were conducted with 60 chronically ill but cognitively competent nursing home patients with a mean age of 80 years, living in 13 nursing homes in the county of Stockholm, Sweden. Quality of nursing home care was assessed through discrepancy between individual priorities (i.e. degree of perceived personal autonomy) and institutional possibility. The results show that there was a high degree of satisfaction with quality of care with regard to meal and shower routines, as well as with the possibilities to watch television, listen to the radio and feel secure. Social relations, on the other hand, was a subject which exposed large discrepancies. Most respondents believed in the importance of social relations whereas results point to a lack of intimacy in the daily living. 相似文献
92.
93.
94.
This follow-up study describes the former students' lasting impressions of a two-week interprofessional course on a training ward aimed at enhancing the understanding of the roles of other professions and the importance of communication for teamwork and for patient care as well as providing an opportunity for profession-specific training. A questionnaire with both closed and open-ended questions was sent to 633 former students two years after the course and 348 (55%) responded. The course was rated as very good and most of the former students had lasting and positive impressions. Ninety-two percent of respondents encouraged teamwork in their present work and 90% wanted to retain the course. The qualitative analysis of the open-ended questions resulted in five categories describing students' perceptions: professional role development, working in teams, tutoring, patient care and future aspects of the course and real world practice. Our results suggest that interprofessional training during undergraduate education provides lasting impressions that may promote teamwork in students' future occupational life. 相似文献
95.
Impact of Early Initiation of Enteral Nutrition on Survival During Pediatric Extracorporeal Membrane Oxygenation
下载免费PDF全文
![点击此处可从《JPEN. Journal of parenteral and enteral nutrition》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Kristin C. Greathouse MS CPNP‐AC Kelly T. Sakellaris MS RD Dmitry Tumin PhD Jacob Katsnelson MD Joseph D. Tobias MD Don Hayes MD Jr. Andrew R. Yates MD 《JPEN. Journal of parenteral and enteral nutrition》2018,42(1):205-211
Introduction: Pediatric data related to safety, tolerance, and outcomes of enteral nutrition (EN) for patients requiring extracorporeal membrane oxygenation (ECMO) are lacking. The objectives of this study were to evaluate early nutrition status and timing of EN initiation on survival during pediatric ECMO. Methods: A single center institutional review board–approved retrospective chart review was performed on all pediatric patients requiring ECMO from October 2008 through December 2013. Demographics, ECMO variables, laboratory values, vasoactive inotropic score (VIS), and nutrition data on day 5 (d5) were collected. Patients receiving parenteral nutrition (PN) were compared with those receiving any EN on d5. Analyses were conducted to identify factors influencing survival to completion of ECMO and to discharge. Results: Forty‐nine patients aged 53 ± 76 months met inclusion criteria. Kaplan‐Meier curves demonstrated greater survival to discharge in patients receiving any EN, compared with only receiving PN (P = .031). EN on d5 of ECMO support (P = .040) and a higher percentage of daily energy intake achieved (P = .013) were protective, whereas a higher VIS was associated with increased mortality (P = .010). Multivariable analysis demonstrated EN was no longer associated with survival to discharge (P = .139), whereas energy intake (P = .021) and VIS (P = .013) remained significant. Conclusions: Pediatric patients who received nutrition that was closer to goal energy intake, as well as those who received any EN early during ECMO, had improved survival to hospital discharge. 相似文献
96.
Ashley C. Newell MD Kelly Davis CPNP‐PC/AC Li Wang MS David Bichell MD Mark A. Clay MD 《JPEN. Journal of parenteral and enteral nutrition》2018,42(1):49-55
Background
Underweight infants with single‐ventricle cardiac physiology have been shown to have increased morbidity, mortality, and resource utilization. The purpose of this study was to determine whether patients who were overweight, as defined by weight‐for‐length z score >90th percentile, were similarly at risk for increased resource utilization, as defined by mechanical ventilation hours (VHs) and intensive care unit length of stay (ICU LOS).Methods
We evaluated resource utilization for 109 patients from our institution who underwent bidirectional Glenn surgery from January 2010 to June 2015 and met prespecified inclusion criteria. Patients were divided into 3 groups: underweight (z score, <5th percentile), normal weight (z score, 5th–90th percentile), and overweight (z score, >90th percentile).Results
ICU LOS was longer in the overweight group (median, 18.5 days) when compared with the under‐ and normal‐weight groups (median LOS, 11 and 9 days, respectively) but did not reach statistical significance. VHs were also increased in the overweight group (median, 72 hours) when compared with the underweight (median, 27 hours) and normal weight (median, 25 hours) groups. This increase in VHs was statistically significant (P = .03).Conclusions
This study suggests that patients with single‐ventricle physiology who are overweight at the time of their bidirectional Glenn surgery may be at risk for increased resource utilization as compared with those who meet or fail to meet their caloric recommendations. These findings represent an underappreciated risk factor in this already‐vulnerable patient population, providing potential opportunity for intervention and improved outcomes. 相似文献97.
In a second update of a systematic review, many new developments in the
combined drug treatment of rheumatoid arthritis (RA) are highlighted. In
early RA patients, step-down bridge therapy that includes corticosteroids
leads to much enhanced efficacy at acceptable or low toxicity. The effects
on joint damage may be persistent, but the symptomatic effects are probably
dependent on continued corticosteroid dosing. In late patients, cyclosporin
improves a suboptimal clinical response to methotrexate, and the triple
combination of methotrexate, sulphasalazine and hydroxychloroquine appears
to be clinically better than the components. Other combinations are either
untested, tested at low sample size, or show negative interaction. In view
of the low volume of evidence, most studies need confirmation by
replication.
相似文献
98.
Pre‐therapy inflammation and coagulation activation and long‐term CD4 count responses to the initiation of antiretroviral therapy
下载免费PDF全文
![点击此处可从《HIV medicine》网站下载免费的PDF全文](/ch/ext_images/free.gif)
99.
100.
Williams MA; Kouroumoussis I; Syndercombe-Court D; Hendry L; Newland AC; Kelsey SM 《Blood》1995,86(11):4234-4242
Monocyte expression and secretion of tumor necrosis factor (TNF) and TNF receptors (TNF-R) p55 and p75 was studied in patients receiving granulocyte-macrophage colony-stimulating factor (GM-CSF) after intensive chemotherapy. TNF expression and secretion of biologically active TNF was increased at regeneration compared with that of patients who had received chemotherapy alone. This effect persisted for several weeks after cessation of growth factor therapy. GM-CSF restored the responsiveness of monocytes to bacterial lipopolysaccharide (LPS), which appeared to be diminished after chemotherapy alone. Expression and secretion of TNF-R p55 and p75 by monocytes was augmented by GM-CSF therapy in association with the increase in TNF protein. We propose that GM-CSF administration after chemotherapy restores the normal responsiveness of monocytes to a secondary stimulus such as LPS and primes monocytes to respond to LPS with increased expression and secretion of TNF and TNF-R. 相似文献