全文获取类型
收费全文 | 182816篇 |
免费 | 35657篇 |
国内免费 | 2421篇 |
专业分类
耳鼻咽喉 | 5538篇 |
儿科学 | 6292篇 |
妇产科学 | 3242篇 |
基础医学 | 7318篇 |
口腔科学 | 2277篇 |
临床医学 | 30126篇 |
内科学 | 53640篇 |
皮肤病学 | 7894篇 |
神经病学 | 17789篇 |
特种医学 | 7510篇 |
外国民族医学 | 4篇 |
外科学 | 45960篇 |
综合类 | 1055篇 |
现状与发展 | 72篇 |
一般理论 | 62篇 |
预防医学 | 10738篇 |
眼科学 | 3951篇 |
药学 | 3292篇 |
中国医学 | 50篇 |
肿瘤学 | 14084篇 |
出版年
2024年 | 699篇 |
2023年 | 4896篇 |
2022年 | 1391篇 |
2021年 | 3533篇 |
2020年 | 6279篇 |
2019年 | 2704篇 |
2018年 | 8036篇 |
2017年 | 7796篇 |
2016年 | 8830篇 |
2015年 | 8946篇 |
2014年 | 16182篇 |
2013年 | 16736篇 |
2012年 | 7048篇 |
2011年 | 7086篇 |
2010年 | 11317篇 |
2009年 | 15056篇 |
2008年 | 7310篇 |
2007年 | 5663篇 |
2006年 | 8075篇 |
2005年 | 5352篇 |
2004年 | 4572篇 |
2003年 | 3477篇 |
2002年 | 3416篇 |
2001年 | 4721篇 |
2000年 | 3994篇 |
1999年 | 4084篇 |
1998年 | 4045篇 |
1997年 | 3803篇 |
1996年 | 3663篇 |
1995年 | 3532篇 |
1994年 | 2199篇 |
1993年 | 1838篇 |
1992年 | 2029篇 |
1991年 | 2050篇 |
1990年 | 1663篇 |
1989年 | 1762篇 |
1988年 | 1548篇 |
1987年 | 1334篇 |
1986年 | 1392篇 |
1985年 | 1192篇 |
1984年 | 957篇 |
1983年 | 888篇 |
1982年 | 799篇 |
1981年 | 654篇 |
1980年 | 616篇 |
1979年 | 706篇 |
1978年 | 637篇 |
1977年 | 673篇 |
1973年 | 563篇 |
1972年 | 598篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
In cystic fibrosis (CF), perturbations of total daily energy expenditure (TDEE) may be a major determinant of altered nutrition and growth. Measurement of TDEE is problematic, though the flex-heart rate method (FHRM) provides a close estimation of TDEE, as compared to the cost-prohibitive, gold standard, the double-labeled water method, and permits estimates of the energy cost of daily activities (ECA) above resting energy expenditure (REE). We hypothesize that alterations in ECA affects TDEE in CF. PURPOSE: To measure components of TDEE in adolescents with CF and normal lung function compared with controls, and to determine whether ECA can be improved by diet and exercise. METHODS: Clinically stable CF subjects (aged 9-13, n=12) and age- and gender-matched controls (n=13) had repeated measurements of TDEE by FHRM, REE, and maximal cardiopulmonary exercise testing (CPET) during a 6-week exercise and diet program. RESULTS: While the mean REE was similar in both groups, ECA was significantly lower in CF adolescents as compared to controls (p=0.02). During CPET, maximal exercise in CF was characterized by hyperventilation, which was unrelated to ventilation-perfusion mismatching. There were no changes in REE after dietary intervention. CONCLUSION: ECA in CF adolescents with normal lung function is lower when compared to healthy controls. These findings support the hypothesis that clinically stable patients with CF have inefficient energy metabolism or alternatively conserve energy during activities of daily living. 相似文献
102.
103.
Fibromyalgia is a syndrome of widespread pain, nonrestorative sleep, disturbed mood, and fatigue. Optimal treatment involves
a multidisciplinary approach with a team of health care providers using pharmacologic and nonpharmacologic treatment. Because
of the heterogeneity of the illness, management should be individualized for the patient. Pharmacologic treatment should address
issues of pain control, sleep disturbance, fatigue, and any underlying coexisting mood disorder. Nonpharmacologic treatment
should include patient education, a regular exercise and stretching program, and cognitive behavioral therapy. All of these
are essential to improving functional capacity and quality of life. This review provides general guidelines in initiating
a successful pharmacologic treatment program for patients with fibromyalgia. 相似文献
104.
105.
The clinical syndrome of tuberculous (TB) meningitis leading to ischemic strokes is rarely seen today in immunocompetent adults native to North America. This entity is also notoriously difficult to diagnose because the presenting symptoms are often nonspecific. The authors describe a case of a man with TB meningitis which progressed to recurrent ischemic cerebral infarcts. 相似文献
106.
107.
108.
109.
Effects of poor glucose handling on arterial stiffness and left ventricular mass in normal children.
AIM: Cardiovascular risk factors can be present in children and young adults. We previously found abnormal microvascular function in children who had glucose intolerance and insulin resistance. The aim of the present study was to investigate whether they also have abnormalities in left ventricular mass (LVM) and arterial stiffness. METHODS: We measured heart dimensions and LVM using echocardiography, and arterial stiffness using pulse wave analysis in 23 children with good glucose handling (postfeeding glucose: 3.9 to 5 mmol/L) and 21 with poor glucose handling (7.7 to 11.4 mmol/L). RESULTS: The time to pulse reflection was slightly shorter in the poorer glucose handlers (mean+/-SD: 143+/-10 vs 153+/-20 ms, P=0.04), suggestive of increased arterial stiffness. Also in this group, there were significant relationships between intraventricular septal thickness, blood pressure and body mass index, but not in the normal glucose handlers. CONCLUSIONS: We have found that normal children who are in the lowest quintile of glucose tolerance in comparison with their peers are exhibiting the first signs of arterial stiffening. In addition, we have seen the beginnings of a relationship between blood pressure, body mass index and left ventricular enlargement in this group. While these changes may not yet be clinically significant, their emergence might be further evidence of early predisposition to cardiovascular disease. 相似文献
110.