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21.
Acute photodermatitis provoked by skin contact with giant hogweed (Heracleum mantegazzianum) and exposure to ultraviolet radiation is a rare cause of phytophotodermatitis in children. We report the case of a 10‐year‐old girl with extensive photodermatitis after contact with giant hogweed and prolonged exposure to sunlight. The lesions involved 10% of the body surface area, mainly the lower extremities. After initial application of topical steroids to the skin erythema, the topical approach was changed due to extensive bullae. Debridement and temporary wound closure with an adequate dressing was undertaken. This is the first case report of application of Suprathel (PolyMedics Innovations, Denkendorf, Germany) on a phytophototoxic burn‐like wound with a favorable outcome. 相似文献
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Ashutosh Verma James Matsunaga Sergey Artiushin Marija Pinne Dirk J. Houwers David A. Haake Brian Stevenson John F. Timoney 《Clinical and Vaccine Immunology : CVI》2012,19(3):452-456
Screening of an expression library of Leptospira interrogans with eye fluids from uveitic horses resulted in identification of a novel protein, LruC. LruC is located in the inner leaflet of the leptospiral outer membrane, and an lruC gene was detected in all tested pathogenic L. interrogans strains. LruC-specific antibody levels were significantly higher in eye fluids and sera of uveitic horses than healthy horses. These findings suggest that LruC may play a role in equine leptospiral uveitis. 相似文献
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Penezić Aleksandra Moriano Roberta Spasić Marija Ćirović Duško 《Parasitology research》2018,117(3):929-931
Parasitology Research - Dirofilaria immitis causes a severe and life-threatening cardio-pulmonary disease in Europe, Asia, Africa, and the Americas; also, zoonotic infections have been reported.... 相似文献
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Uroš Rajkovič Marija Milavec Kapun Dejan Dinevski Vesna Prijatelj Marija Zaletel Olga Šušteršič 《Journal of medical systems》2016,40(9):198
Health documentation is a prerequisite for good and sustainable health and social care. It is especially important for patient involvement and their empowerment. A transition from paper to e-documentation together with the electronic patient record should be based on thorough knowledge of the current state of documentation and its usages. The main objective of this paper was to analyse which documents and work methods of documenting processes within nursing are being used within different environments. Furthermore, what are the main reasons for their discrepancies from theoretical approaches and best practices. The analysis is based on a survey carried out on all three levels of healthcare. The survey questionnaire consisted of 12 questions to which responded 286 nursing teams from community health centres, hospitals and retirement homes in Slovenia. The results point to diversity in documenting as well as lack of interoperability. This is reflected in a great number of different documents. All phases of the nursing process were being documented in only 31.8 % of cases. The main reasons for this can be attributed to work organisation, different definitions of data-set requirements and inadequate knowledge by nurses. Survey results pointed out a need for the renewal of nursing documentation towards a more uniform system based on contemporary health technologies. 相似文献
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Successful use of sirolimus for refractory atrial ectopic tachycardia in a child with cardiac rhabdomyoma 下载免费PDF全文
Sanja Ninic MD Marija Kalaba MD Bosiljka Jovicic MD Vladislav Vukomanovic MD PhD Sergej Prijic MD PhD Biljana Vucetic MD Ruzica Kravljanac MD PhD Ana Vujic MD PhD Jovan Kosutic MD PhD 《Annals of noninvasive electrocardiology》2017,22(4)
Cardiac rhabdomyomas are common in tuberous sclerosis. We report a child who developed rhabdomyoma related arrhythmia refractory to antiarrhythmic drug therapy. Reversion of the atrial ectopic tachycardia was achieved with mammalian target of rapamycin pathway (mTOR) inhibitor sirolimus. As per our knowledge, this is the first time that sirolimus has been successfully used in this setting. 相似文献
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Barriers to access to opioid medicines for patients with opioid dependence: a review of legislation and regulations in eleven central and eastern European countries 下载免费PDF全文
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Alice Guazzelli Parisa Meysami Emyr Bakker Ezio Bonanni Constantinos Demonacos Marija Krstic-Demonacos 《Expert opinion on investigational drugs》2013,22(8):719-732
Introduction: Malignant pleural mesothelioma (MPM) is a rare neoplasm with a poor prognosis, as current therapies are ineffective. Despite the increased understanding of the molecular biology of mesothelioma, there is still a lack of drugs that dramatically enhance patient survival.Area Covered: This review discusses recent and complete clinical trials supported by the NIH, other U.S. Federal agencies, universities and organizations found on clinicaltrials.gov. Firstly, chemotherapy-based trials are described, followed by immunotherapy and multitargeted therapy. Then we introduce drug repositioning and the use of drug docking as tools to find new interesting molecules. Finally, we highlight potential molecular pathways that may play a role in mesothelioma biology and therapy.Expert Opinion: Numerous biases are present in the clinical trials due to a restricted number of cases, inappropriate endpoints and inaccurate stratification of patients which delay the finding of a treatment for MPM. The most crucial issue of independent research for MPM is the lack of more substantive funding to translate these findings to the clinical setting. However, this approach is not necessarily scientific given the low mutational load of mesothelioma relative to other cancers, and therefore patients need a more solid rationale to have a good chance of successful treatment 相似文献