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71.
Geneviève Cadieux Vanessa Redditt Daniela Graziano Meb Rashid 《Journal of immigrant and minority health / Center for Minority Public Health》2017,19(1):6-14
Several outbreaks of varicella have occurred among refugees. We aimed to estimate the prevalence of varicella susceptibility among refugees, and identify risk factors for varicella susceptibility. All refugees rostered at Crossroads Clinic in Toronto, Canada in 2011–2014 were included in our study. Varicella serology was assessed at the initial visit. Refugees’ age, sex, education, time since arrival, and climate and population density of birth country were abstracted from the chart. Multivariate logistic regression was used to identify risk factors for varicella susceptibility. 1063 refugees were rostered at Crossroads Clinic during the study; 7.9 % (95 % CI 6.1, 9.7) were susceptible to varicella. Tropical climate (OR 3.20, 95 % CI 1.53, 6.69) and younger age (ORper year of age 0.92, 95 % CI 0.88–0.96) were associated with increased varicella susceptibility. These risk factors for varicella susceptibility should be taken into account to maximize the cost-effectiveness of varicella prevention strategies among refugees. 相似文献
72.
Yvan?L’Homme Rapha?l?Sansregret étienne?Plante-Fortier Anne-Marie?Lamontagne Geneviève?Lacroix Mourad?Ouardani Jonathan?Deschamps Geneviève?Simard Carole?Simard 《Archives of virology》2009,154(4):581-593
Noroviruses and sapoviruses are members of the family Caliciviridae and emerging enteric pathogens of humans and animals.
Since their discovery and characterization in swine, relatively few strains have been described in detail. In order to investigate
their genetic diversity, a total of 266 fecal samples collected in the province of Quebec, Canada, between 2005 and 2007 were
screened for the presence of caliciviruses by RT-PCR using broadly reactive primers. Genetically heterogeneous caliciviruses
were detected on the majority of farms. Typical noroviruses related to known swine genotypes were present on 20% of the farms.
Sapoviruses were detected on 75% of the farms and were the most heterogeneous group. Further characterization of selected
strains in their 3′ end parts was carried out for their classification and unveiled possibly new clusters of sapoviruses.
No human-like noroviruses or sapoviruses were detected in the present study.
GenBank accession numbers of all sequences described in this study are indicated in the figure legends. 相似文献
73.
Significance of Diminished Factor XIII in Crohn's Disease 总被引:1,自引:0,他引:1
74.
Lewden C Raffi F Cuzin L Cailleton V Vildé JL Chêne G Allavena C Salamon R Leport C 《The Journal of infectious diseases》2002,186(5):710-714
This study attempted to identify factors associated with mortality among human immunodeficiency virus (HIV)-infected adults starting a protease inhibitor (PI)-containing therapy. Among 1155 patients consecutively enrolled in the APROCO study between May 1997 and June 1998, clinical characteristics were as follows: median age, 36 years; median baseline CD4 cell count, 288 cells/mm(3); and median baseline plasma HIV RNA load, 4.4 log(10) copies/mL. After a median follow-up of 27 months, 48 deaths had occurred, of which 44% were related to acquired immune deficiency syndrome. The mortality rate was 2.9% at 12 months. When both data at baseline and data at 4 months after the start of PI therapy were considered, factors independently associated with mortality were (Cox model) low baseline plasma creatinine level, low school education level, low CD4 cell count at 4 months, low hemoglobin level, and elevated hepatic transaminase levels. Thus, social context plus clinical and biologic data, including the 4-month response to treatment, must be considered in treatment of HIV-infected patients. 相似文献
75.
Soulié C Malet I Lambert-Niclot S Tubiana R Thévenin M Simon A Murphy R Katlama C Calvez V Marcelin AG 《AIDS (London, England)》2008,22(16):2212-2214
Resistance to CCR5 antagonists can be driven by mutations in gp120. Sequences from 323 anti-CCR5 naive patients were analyzed for the presence of previously described in-vivo or in-vitro resistance mutations to CCR5 antagonists located in the V3 loop of gp120. The V3 loop region was rather polymorphic, and 7.3% of patients showed viruses with combinations of mutations in V3 loop previously described to be involved in maraviroc resistance, a licensed CCR5 antagonist. 相似文献
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78.
Alize Raimbeau Marc-Antoine Pistorius Yann Goueffic Jrme Connault Pierre Plissonneau-Duquene Blandine Maurel Jean Reignier Karim Asehnoune Mathieu Artifoni Quentin Didier Giovanni Gautier Jean-Nel Trochu Bertrand Rozec Chan NGohou Ccile Durant Pierre Pottier Julien Denis Le Sve Nicolas Brebion Christian Agard Olivier Espitia 《Medicine》2021,100(20)
Upper extremity digital ischaemia (UEDI) is a rare heterogeneous condition whose frequency is 40 times less than that of toe ischaemia. Using a large cohort, the aim of this study was to evaluate aetiologies, prognosis and midterm clinical outcomes of UEDI.All patients with UEDI with or without cutaneous necrosis in a university hospital setting between January 2000 to December 2016 were included. Aetiologies, recurrence of UEDI, digital amputation and survival were analyzed retrospectively.Three hundred twenty three patients were included. UEDI due to cardio-embolic disease (DICE) was the highest occurring aetiology with 59 patients (18.3%), followed by DI due to Systemic Sclerosis (SSc) (16.1%), idiopathic causes (11.7%), Thromboangiitis obliterans (TAO) (9.3%), iatrogenic causes (9.3%), and cancer (6.2%). DICE patients tended to be older and featured more cases with arterial hypertension whereas TAO patients smoked more tobacco and cannabis. During follow-up, recurrences were significantly more frequent in SSc than in all other tested groups (P < .0001 vs idiopathic and DICE, P = .003 vs TAO) and among TAO patients when compared to DICE patients (P = .005). The cumulated rate of digital amputation was higher in the SSc group (n = 18) (P = .02) and the TAO group (n = 7) (P = .03) than in DICE (n = 2).This retrospective study suggests that main aetiologies of UEDI are DICE, SSc and idiopathic. This study highlights higher frequency of iatrogenic UEDI than previous studies. UEDI associated with SSc has a poor local prognosis (amputations and recurrences) and DICE a poor survival. UEDI with SSc and TAO are frequently recurrent. 相似文献
79.
David Emmanuelle Fauvernier Mathieu Saadoun David Gerfaud-Valentin Mathieu Maurcort-Boulch Delphine Sève Pascal Jamilloux Yvan 《Clinical rheumatology》2022,41(6):1749-1758
Clinical Rheumatology - To examine the mortality rates and causes of death among French decedents with Behçet’s disease (BD). Data collected between 1979 and 2016 by the French... 相似文献