Clinical observation of senile idiopathic nephrotic syndrome treated with integrated traditional chinese and western medicine

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复苏困难的重症瓣膜病人心肌保护方法

目的 总结9例复苏困难的重症瓣膜病患者成功复苏经验，尝试心肌保护新方法。方法对经多次除颤不能复苏的重症瓣膜病患者，采用再次阻断升主动脉，行4：1半钾温冷血停搏液诱停加纯温血持续灌注，待心脏复苏后再开放升主动脉的方法。结果9例复苏困难的重症瓣膜病患者均自动复苏。结论再次阻断升主动脉，行4：1半钾温冷血停搏液诱停加纯温血(不含停搏液)持续灌注，待心脏复苏后再开放升主动脉的方法为复苏困难的心脏直视手术患者成功复苏提供了新方法。     

胸锁乳突肌锁骨膜瓣重建声门下喉腔

用胸锁乳突肌锁骨膜瓣重建喉癌切除后声门下喉腔１ 例。术后９ 个月复查缺损处出现骨化区,随访１ 年,呼吸发音良好,喉腔粘膜光滑,无狭窄,肿瘤无复发。对胸锁乳突肌锁骨膜瓣的适应证、手术方法及优点进行讨论。胸锁乳突肌锁骨膜瓣安全可靠,就近取材,血供良好,手术方法简便,可一期完成,并发症少,是重建声门下喉、气管腔的良好组织。     

PCNA 在颈动脉粥样硬化斑块形成血管中的表达

目的：探讨颈动脉粥样硬化斑块形成后血管内膜中 PCNA 的表达。方法：我院2006年8月～2013年6月 CEA 术后血管内膜80例为实验组,对照组选取骨肿瘤截肢正常动脉血管内膜标本10例,对两组进行免疫组织化学染色,通过对阳性细胞数、着色强弱等指标的观察,对比两组间 PCNA 表达的阳性分级。结果：实验组与对照组相比较,两组 PCNA 阳性分级对比具有显著性差异。结论：PCNA 的表达增强在颈动脉粥样硬化斑块形成过程中可促进血管平滑肌细胞增殖,为粥样硬化斑块形成的重要影响因子。     

重症胰腺炎外科治疗分析(附79例疗效分析)

目的 :探讨急性重症胰腺手术治疗及术后灌洗引流。方法 :对急性重症胰腺炎采取胰床广泛切开清除坏死组织、术后灌洗引流及综合治疗。结果 :由 1992年前 ,单纯引流 2 6例 ,死亡 15例 ,死亡率 5 7.6 9%。 1992年后 ,改进手术及术后灌洗引流 5 3例 ,死亡 12例 ,死亡率为 2 2 .6 4% ,结论 :重症胰腺炎经手术及术后灌洗引流 ,综合治疗死亡率明显下降     

Novel heterozygous F7 gene mutation (c. C1286T) associated with congenital factor VII deficiency: A case report and literature review

BackgroundCongenital factor VII (FVII) deficiency is a rare inherited autosomal recessive disorder characterized by prolongation of prothrombin time and low FVII coagulation activity, which may increase the risk of bleeding.Case presentationA 66‐year‐old man with acute postoperative intracranial hemorrhage was transferred to our hospital owing to coagulation dysfunction. In coagulation tests, the FVII coagulation activity was less than 2%. Genetic analysis of the gene encoding FVII identified compound heterozygous mutations: c. 681+1 G>T and c. C1286T (p. Ala429Val).ConclusionsTo our knowledge, this is the first report describing the c. C1286T (p. Ala429Val) mutation in the FVII‐encoding gene. We suggest that these mutations resulted in the reduced FVII activity and abnormal clotting in our patient after brain surgery.     

空肠弯曲菌保存方法的比较

空肠弯曲菌是近年来在全球范围内被广泛重视的人畜共患病病原菌,该菌培养条件苛刻,菌株不易保存。为了解决保存难这一难题,此实验对七种通常用于空肠弯曲菌保存的方法,进行了详细的比较和研究。结果表明温度在-70℃适合于菌株的长期保存,温度在2℃～8℃保存时间较短,但操作简便,适用于菌株的暂时保存。     

儿童颅内错构瘤与癫痫的外科治疗并文献复习——附3例报道

目的 探讨儿童颅内错构瘤与癫痫的关系以及外科治疗方法.方法 回顾性总结3例儿童颅内错构瘤与癫痫病例.其中男2例,女1例.年龄5～5.5岁.初发病年龄自出生后1月余～5个月.首发症状均为癫痫,其中2例为痴笑性发作伴其他症状,1例为全身性发作.3例均无性征发育异常.3例均行外科手术:翼点入路1例、经胼胝体-穹隆间入路1例、经额-颞开颅1例.术中均进行脑皮质和错构瘤部位的脑电图监测.结果 颞叶内侧错构瘤全切1例,下丘脑错构瘤大部切除2例,术后均无并发症.经过10～15个月的随访,2例癫痫发作明显减少(Engel-Ⅱa级),1例癫痫发作程度减轻(Engel-Ⅲ级).结论 儿童错构瘤所致的癫痫是一种药物难治性癫痫.外科手术可减轻、甚至能完全控制癫痫发作.     

Non-Destruction Evaluation Method for Long-Term Oxidation Behavior of SiC/SiC Composites with Different Preforms in Wet Oxygen

The implementation of SiC fiber reinforced SiC/SiC composites to aero-engine hot components has attracted wide attention, due to their many excellent properties. Along these lines, in order to predict the oxidation behavior of the material in extreme environments and to explore the effect of different preforms on the oxidative behavior of the composites, four SiC/SiC composites, with different preforms, were oxidized under environmental conditions of pressure of 12 kPa H₂O:8 kPa O₂:80 kPa Ar, at 1400 °C temperature. Moreover, the morphology and defect distribution of the samples were characterized by carrying out scanning electron microscopy, and micro-computed X-ray tomography measurements. Furthermore, the relation between the micro- and macro-scales was established, so as to be able to predict the oxidation behavior of the composites; not only the quantitative relationship between the mass change rate and the defect volume change rate, but also the combination of micro-computed X-ray images.