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101.
Linus Olson Carina Lothian Ulrika dn Hugo Lagercrantz Nicola J. Robertson Fredrik Setterwall 《Materials》2021,14(23)
(1) Background: The field of medicine requires simple cooling materials. However, there is little knowledge documented about phase change materials (PCM) covering the range of 28 to 40 degrees Celsius, as needed for medical use. Induced mild hypothermia, started within 6 h after birth, is an emerging therapy for reducing death and severe disabilities in asphyxiated infants. Currently, this hypothermia is accomplished with equipment that needs a power source and a liquid supply. Neonatal cooling is more frequent in low-resource settings, where ~1 million deaths are caused by birth-asphyxia. (2) Methods: A simple and safe cooling method suitable for medical application is needed for the 28 to 37.5 °C window. (3) Results: Using empirical experiments in which the ingredients in Glauber salt were changed, we studied the effects of temperature on material in the indicated temperature range. The examination, in a controlled manner, of different mixtures of NaCl, Na2SO4 and water resulted in a better understanding of how the different mixtures act and how to compose salt solutions that can satisfy clinical cooling specifications. (4) Conclusions: Our Glauber salt solution is a clinically suited PCM in the temperature interval needed for the cooling of infants suffering from asphyxia. 相似文献
102.
Kocevar VS Bisgaard H Jönsson L Valovirta E Kristensen F Yin DD Thomas J 《Chest》2004,125(5):1680-1684
BACKGROUND: We assessed variations in hospitalization parameters and costs among asthmatic children in four Nordic countries by geographic location and age groups. METHODS: Cross-sectional, county-level aggregate data on asthma-related hospitalizations in 1999, obtained from public national databases for children < 15 years old from Denmark, Sweden, Norway, and Finland, together with country-specific asthma management cost were used to estimate the incidence of first hospital admission (per 1,000), length of hospital stay (LOS), and hospitalization cost. Longitudinal patient-specific data from 1998/1999 were used to calculate the relative hazard of readmission (RHR) using a multivariate Cox proportional hazards model. RESULTS: Nordic incidence of first hospital admission in 1999 was 2.17 per 1,000 children, readmission was noted in 16% of the patients, mean LOS was 2.64 days, and total hospitalization cost was almost 14 million dollars. Hospitalization incidence, RHR, and costs were significantly higher in children < 5 years old compared with school children 6 to 14 years old. Hospital LOS, incidence of first hospital admission, and cost per child were the highest in Denmark, though RHR did not differ significantly from Sweden. CONCLUSIONS: Large variations in all parameters were observed between and within countries. Given the similarities among the four countries studied, these results may, among other reasons, indicate different efficiencies of the various asthma management plans between and within them. The presented measures of hospitalization patterns could prove to be valuable quality-of-care measures to guide further improvements in asthma management. 相似文献
103.
We report a family of a man and two of his three male children who all had torsion of the left testis, all at the age of 15 years
and all occurring during sleep. Their management and the possible modes of inheritance are discussed. 相似文献
104.
Zichen Lin Li‐Qiao R. Ling Mabel Ng Laith Matlub Kunal Mehta Roshine A. Linus Mitchell J. Looker Yovita Melia Junhan Loong Rita Paolini Camile S. Farah Antonio Celentano 《Journal of oral pathology & medicine》2021,50(1):118-121
Tumour progression allows for aberrant angiogenesis. Consequently, cancer‐associated thrombosis is a prevalent complication that is coupled with poor prognosis. Anticoagulants have therefore been prescribed with chemotherapeutic agents to target potential thrombo‐embolic risk. A systematic review was carried out to summarise existing evidence on the interactions between anticoagulants and oral cancer. This treatment paradigm has demonstrated beneficial results in some oncology patients, thus associating anticoagulants with anticancer effects. Increasing prevalence of oral cancer presents a need to source alternative therapeutic means to prevent disease progression, and thus the use of anticoagulants in these patients may provide an avenue for this to occur. The paucity of evidence regarding the interactions between oral squamous cell carcinoma and anticoagulants emphasises the urgency with which further research should be conducted. 相似文献
105.
106.
Vicki A. Thomson Ophélie Lebrasseur Jeremy J. Austin Terry L. Hunt David A. Burney Tim Denham Nicolas J. Rawlence Jamie R. Wood Jaime Gongora Linus Girdland Flink Anna Linderholm Keith Dobney Greger Larson Alan Cooper 《Proceedings of the National Academy of Sciences of the United States of America》2014,111(35):E3585-E3586
107.
Linus I Okeke Augustine O Takure Sikiru A Adebayo Olukayode Y Oluyemi Abimbola AA Oyelekan 《BMC urology》2012,12(1):1-3
Background
Secondary urethral stone although rare, commonly arises from the kidneys, bladder or are seen in patients with urethral stricture. These stones are either found in the posterior or anterior urethra and do result in acute urinary retention. We report urethral obstruction from dislodged bladder diverticulum stones. This to our knowledge is the first report from Nigeria and in English literature.Case presentation
A 69 year old, male, Nigerian with clinical and radiological features of acute urinary retention, benign prostate enlargement and bladder diverticulum. He had a transurethral resection of the prostate (TURP) and was lost to follow up. He re-presented with retained urethral catheter of 4months duration. The catheter was removed but attempt at re-passing the catheter failed and a suprapubic cystostomy was performed. Clinical examination and plain radiograph of the penis confirmed anterior and posterior urethral stones. He had meatotomy and antegrade manual stone extraction with no urethra injury.Conclusions
Urethral obstruction can result from inadequate treatment of patient with benign prostate enlargement and bladder diverticulum stones. Surgeons in resource limited environment should be conversant with transurethral resection of the prostate and cystolithotripsy or open prostatectomy and diverticulectomy. 相似文献108.
Zhang Yuehui Hu Min Yang Fan Zhang Yizhuo Ma Shuting Zhang Dongqi Wang Xu Sferruzzi-Perri Amanda Nancy Wu Xiaoke Brännström Mats Shao Linus R. Billig Håkan 《Journal of molecular medicine (Berlin, Germany)》2021,99(10):1427-1446
Journal of Molecular Medicine - In this study, we show that during normal rat pregnancy, there is a gestational stage-dependent decrease in androgen receptor (AR) abundance in the gravid uterus and... 相似文献
109.
110.
Linus B. Grabenhenrich MD MPH Hannah Gough Oliver Nitsche Johannes Forster Antje Schuster Dirk Schramm Carl-Peter Bauer Ute Hoffmann John Beschorner Petra WagnerRenate Bergmann MD Karl Bergmann Paolo Maria Matricardi Ulrich Wahn Susanne Lau Thomas Keil 《The Journal of allergy and clinical immunology》2014