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21.
BackgroundArtificial insemination with the husband’s semen (AIH) is an economical and noninvasive method of infertility treatment. However, AIH’s pregnancy rate is much lower than in vitro fertilization (IVF) as its multiple and complex uncertainty factors. Semen quality has been one of the main factors which affect the pregnancy outcome of AIH.MethodsThe relevant parameters of 1,142 AIH cycles were retrospectively studied, including the general parameters and the semen quality parameters among clinical pregnancy, biochemical pregnancy, non-pregnancy group, age, infertility duration, infertility type, body mass index (BMI), cycle count, morphology in previously semen examination, and semen quality parameters on the day of AIH.ResultsThe statistically significant difference was only found on processed total non-forward and non-motile sperm count (N-TFMSC). The mean processed N-TFMSC in the biochemical pregnancy group was 6.37±4.27 million, significantly higher than the other two groups (vs. 4.40±3.15 million or vs. 4.48±3.60 million, P<0.05). The study was then divided into two groups according to processed N-TFMSC, Group 1 ≤5.0 million, and Group 2 >5.0 million. A statistical increase in biochemical pregnancy rate was observed when the processed N-TFMSC was >5.0 million (2.72% vs. 0.90%).ConclusionsProcessed N-TFMSC may be one of the independent factors on AIH’s outcome; it should be given equal attention the same as processed total forward motile sperm count (TFMSC). 相似文献
22.
目的通过对大鼠股骨骨折早期局部应用重组人骨保护素Fc融合蛋白(OPG-Fc),研究调节骨保护素(OPG)和核因子-κB受体活化因子配体(RANKL)的表达变化对骨折早期的影响,探讨其表达调节方式及作用机制。方法 48只雌性SD大鼠随机分成实验组和对照组,每组24只。建立大鼠股骨骨折模型,于术后第7天、第14天、第21天、第28天4个时间节段分批处死模型,标本切片后通过HE染色观察骨折愈合情况,免疫组织化学染色研究破骨细胞数量变化。结果 HE染色示单纯骨折组呈典型骨折愈合过程,而骨折局部注射OPG组骨痂形成及改造提前,骨折愈合加速。免疫组织化学染色显示在第7天、第14天、第21天、第28天各个时间节段单纯骨折组破骨细胞计数值均高于骨折应用OPG组,差异有统计学意义(P0.05)。结论骨折早期调节RANKL表达,当RANKL/OPG比值减小时,骨折局部破骨细胞减少,骨痂形成增多,骨折愈合加速。 相似文献
23.
Ming-Yeh Yang Ching-Yuan Huang Tina H.T. Chiu Kai-Chih Chang Ming-Nan Lin Liang-Yü Chen Anren Hu 《Yao wu shi pin fen xi = Journal of food and drug analysis.》2019,27(2):494-501
Vitamin D is responsible for multiple metabolic functions in humans. Rickets are the most common disease caused by vitamin D deficiency. It is caused by poor calcium intake resulting in poor serum-ionized calcium. The purpose of this study is to develop a rapid, sensitive, and feasible method to determine the 25-hydroxy-vitamin D3 (25(OH)D3) levels in blood samples for clinical assessment. In this study, gas chromatography coupled mass spectrometry with trimethylsilyl derivatization (TMS-GC-MS) is the most suitable protocol for quantitative analyses of 25(OH)D3. Performance of method was evaluated and compared with liquid chromatography and immunoassay. Method validation has been carried out with plasma specimens. The limit of quantitation of TMS-GC-MS method is 1.5 ppb with good linear correlation. Furthermore, the dietary intake and nutritional status of vegetarian and non-vegetarians in Taiwan were assessed by our validated method. As a result, this vitamin D nutrition survey demonstrates that most Taiwanese people have insufficient vitamin D. Due to dietary habits; the male vegans may have the highest risk of vitamin D deficiency. 相似文献
24.
25.
OBJECTIVES: To assess the effectiveness and safety of additional bedtime H2‐receptor antagonists (H2RAs) in suppressing nocturnal gastric acid breakthrough (NAB) via a systematic review. METHODS: Eligible trials were identified by searching the Cochrane Central Register of Controlled Trials (CENTRAL) (Cochrane Library Issue 2, 2004), MEDLINE (January 1966–June 2004), EMBASE (January 1980–June 2004) and CINAHL (January 1982–June 2004). Additional hand‐searching was conducted on the proceedings of correlated conferences, eight important Chinese journals and references of all included trials. All randomized controlled trials evaluating H2RAs for the control of NAB were eligible for inclusion. The systematic review was conducted using methods recommended by The Cochrane Collaboration. RESULTS: Only two randomized crossover studies, comprising 32 participants, met the inclusion criteria. Because the design, dosage and duration of the treatments were different between the studies, it was not possible to conduct meta‐analysis. There were no consistent conclusions found between the two included studies in evaluating H2RAs for the control of NAB. CONCLUSIONS: No implications for practice at this stage can be concluded. Appropriately designed large‐scale randomized controlled trials with long‐term follow up are needed to determine the effects of additional bedtime H2RAs in suppressing NAB. 相似文献
26.
网络环境下医学专题检索服务的深化 总被引:3,自引:2,他引:1
分析网络环境下图书馆定题服务的现状和价值,提出跟踪服务的方式,进行分阶段的、具体的定题服务,并实例分析分阶段定题服务的优势。 相似文献
27.
The spine, pelvic bones and long bones of the lower extremities are common sites for insufficiency fractures. Cases of sternum insufficiency fractures have been rarely reported in an elderly patient. Insufficiency fracture tends to occur in bones with decreased mechanical strength. It tends to occur in elderly patients, especially in postmenopausal women, with underlying diseases. We describe a case of sternum insufficiency fracture in a patient with rheumatoid arthritis and systemic lupus erythematosus on long-term corticosteroid therapy diagnosed in an emergency setting. Sternum insufficiency fracture is a rare cause of chest pain. This case serves to remind the emergency physician to remain vigilant for other noncardiac and nontraumatic causes of chest pain. If diagnosed accurately, these patients can be discharged and treated as outpatients. 相似文献
28.
目的:通过比较不同中医证型的ICU危重症患者的APACHEⅡ评分,同时对比两组死亡率,评价中医辨证在预后判断中的临床意义。方法:对纳入研究的85例ICU危重症患者于入ICU及出ICU时分别进行中医辨证,分为阳类证和阴类证两型,对所有病人进行APACHEⅡ评分,比较两型病人在进入ICU及出ICU时的APACHEⅡ分值,并与死亡率比较。结果:初始为阴类证的患者在入ICU及出ICU时的APACHEⅡ评分显著高于初始为阳类证的患者(P=0.0001及F〈0.05),死亡率亦显著高于阳类证患者(P=0.0369):治疗后由阳类证转为阴类证患者APACHEⅡ评分较维持阳类证者增高(P=0.0161),而阴类证转为阳类证的患者APACHEⅡ分值较维持阴类证者减低(P=0.0424)。结论:中医证型对危重症的病情程度及预后判断有较好的预测价值,阴类证患者的预后较阳类证患者差,证型转换可能引起预后改变。 相似文献
29.
体重指数分级标准应用方法的探讨 总被引:1,自引:0,他引:1
目的探讨按照体重指数分级标准计算出的体重值应用表的实用价值。方法将身高作为选定变量,其变量值间距为1 cm,按照体重指数分级标准上、下限值,分别乘以身高2(m2),即求出相对应的体重(kg),依此制成应用表。判定时依据身高和实测的体重,对照应用表得出其体重指数分级范围。结果制成并列出以体重值查对其相对应危险值应用表。结论本查对表适用于大规模的预防性健康体检。在人体生长发育阶段能做到自身动态监测,对早期预防肥胖症具有积极作用。 相似文献
30.