全文获取类型
收费全文 | 993723篇 |
免费 | 72244篇 |
国内免费 | 2657篇 |
专业分类
耳鼻咽喉 | 13810篇 |
儿科学 | 26490篇 |
妇产科学 | 24649篇 |
基础医学 | 140050篇 |
口腔科学 | 30671篇 |
临床医学 | 87098篇 |
内科学 | 194836篇 |
皮肤病学 | 20649篇 |
神经病学 | 76543篇 |
特种医学 | 38686篇 |
外国民族医学 | 87篇 |
外科学 | 159816篇 |
综合类 | 22617篇 |
现状与发展 | 11篇 |
一般理论 | 255篇 |
预防医学 | 66470篇 |
眼科学 | 22835篇 |
药学 | 77915篇 |
19篇 | |
中国医学 | 4067篇 |
肿瘤学 | 61050篇 |
出版年
2021年 | 7407篇 |
2019年 | 7374篇 |
2018年 | 11005篇 |
2017年 | 8744篇 |
2016年 | 9399篇 |
2015年 | 10782篇 |
2014年 | 14307篇 |
2013年 | 20597篇 |
2012年 | 28924篇 |
2011年 | 30606篇 |
2010年 | 17885篇 |
2009年 | 16506篇 |
2008年 | 29048篇 |
2007年 | 30244篇 |
2006年 | 30876篇 |
2005年 | 29603篇 |
2004年 | 28251篇 |
2003年 | 27066篇 |
2002年 | 26353篇 |
2001年 | 56044篇 |
2000年 | 57900篇 |
1999年 | 47825篇 |
1998年 | 11125篇 |
1997年 | 9840篇 |
1996年 | 9899篇 |
1995年 | 9207篇 |
1994年 | 8518篇 |
1993年 | 7785篇 |
1992年 | 35705篇 |
1991年 | 34090篇 |
1990年 | 32891篇 |
1989年 | 32007篇 |
1988年 | 29103篇 |
1987年 | 28335篇 |
1986年 | 26370篇 |
1985年 | 25204篇 |
1984年 | 17899篇 |
1983年 | 15191篇 |
1982年 | 7851篇 |
1979年 | 15820篇 |
1978年 | 10635篇 |
1977年 | 9100篇 |
1976年 | 7895篇 |
1975年 | 8646篇 |
1974年 | 10486篇 |
1973年 | 9881篇 |
1972年 | 9373篇 |
1971年 | 8864篇 |
1970年 | 8430篇 |
1969年 | 7932篇 |
排序方式: 共有10000条查询结果,搜索用时 500 毫秒
41.
Annals of Nuclear Medicine - The Response Evaluation Criteria In Solid Tumors (RECIST) is the most used radiological method for evaluating response after peptide receptor radionuclide therapy... 相似文献
42.
Claire Letournel François Babinet Bénédicte Allard Vincent Montecot 《Néphrologie & thérapeutique》2019,15(1):51-58
Objective
The “Centre Hospitalier Francois Dunan” is located on an isolated island and ensures patients care in hemodialysis thanks to telemedicine support. Many research studies have demonstrated the importance of hemodialysis fluids composition to reduce morbidity in patients on chronic hemodialysis. The aim of this study was to identify the risks inherent in the production of dialysis fluids in a particular context, in order to set up an improvement action plan to improve risk control on the production of dialysis fluids.Methods
The risk analysis was conducted with the FMECA methodology (Failure Mode, Effects and Criticality Analysis) by a multi professional work group. Three types of risk have been reviewed: technical risks that may impact the production of hemodialysis fluids, health risks linked with chemical composition and health risks due to microbiological contamination of hemodialysis fluids.Results
The work group, in close cooperation with the expert staff of the dialysis center providing telemedicine assistance, has developed an action plan in order to improve the control of the main risks brought to light by the risk analysis.Conclusion
The exhaustive analysis of the risks and their prioritisation have permitted to establish a relevant action plan in this improving quality of dialysis fluids approach. The risk control of dialysis fluids is necessary for the security of dialysis sessions for patients, even more when these sessions are realized by telemedicine in Saint-Pierre-et-Miquelon. 相似文献43.
44.
Dalton Luiz Schiessel Ricardo K. Yamazaki Marcelo Kryczyk Isabela Coelho de Castro Adriana A. Yamaguchi Danielle C. T. Pequito 《Nutrition and cancer》2016,68(8):1369-1380
Objective: Polyunsaturated fatty acids n-3 (PUFA n-3) have shown effects in reducing tumor growth, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) abundantly present in fish oil (FO). When these fatty acids are provided in the diet, they alter the functions of the cells, particularly in tumor and immune cells. However, the effects of α-linolenic fatty acid (ALA), which is the precursor of EPA and DHA, are controversial. Thus, our objective was to test the effect of this parental fatty acid. Methods: Non-tumor-bearing and tumor-bearing Wistar rats (70 days) were supplemented with 1 g/kg body weight of FO or Oro Inca® (OI) oil (rich in ALA). Immune cells function, proliferation, cytokine production, and subpopulation profile were evaluated. Results: We have shown that innate immune cells enhanced phagocytosis capacity, and increased processing and elimination of antigens. Moreover, there was a decrease in production of pro-inflammatory cytokines (tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6)) by macrophages. Lymphocytes showed decreased proliferation capacity, increased cluster of differentiation 8 (CD8+) subpopulation, and increased TNF-α production. Conclusions: Oil rich in ALA caused similar immune modulation in cancer when compared with FO. 相似文献
45.
46.
47.
48.
A case of bullous pemphigoid associated with psoriasis vulgaris showing Hailey–Hailey disease‐like histopathological changes in regenerated epidermis without genomic mutation in ATP2C1 or ATP2A2 gene 下载免费PDF全文
49.
F. Fruzzetti G. Palla A. Sbrana T. Simoncini M. R. Sessa 《Gynecological endocrinology》2020,36(10):938-940
AbstractObjective: To understand the origin of extremely high gonadotropin levels in a perimenopausal woman.Methods: A 52-year-old woman with a 2?months of amenorrhea followed spontaneous menstrual cycles recovery was referred to our outpatient clinic with elevated follicle-stimulating hormone (FSH, 483 mUI/ml), luteinizing hormone (LH, 475 mUI/ml) and prolactin (PRL, 173?ng/ml). She was known to take levosulpiride. The gonadotropin levels did not fit with the clinical features.Results: A gonadotroph tumor was ruled out. Further analysis confirmed constantly high FSH, LH and PRL levels. The measurements were repeated using different analytical platforms with different results. After serial dilutions, nonlinearity was present suggesting an immunoassay interference. After post-polyethylene glycol recovery, hormone levels appeared in the normal range. Anti-goat antibodies were recognized in the serum of the patient.Conclusions: This case report shows a case of falsely abnormal high gonadotropin and PRL levels in a woman during menopause transition. In the clinical practice the evaluation of gonadotropin profile is not recommended at this age, but the abnormal levels stimulated further evaluation. An interference in the assay due to anti-goat antibodies resulted in abnormally high level of FSH and LH. A strict collaboration between clinicians and the laboratory is needed, when laboratory findings do not correspond to clinical findings. 相似文献
50.
T. Wu L. G. Trahair M. J. Bound C. F. Deacon M. Horowitz C. K. Rayner K. L. Jones 《Diabetic medicine》2015,32(5):595-600