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排序方式: 共有48条查询结果,搜索用时 15 毫秒
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Postmenopausal osteoporosis: simple screening method for diagnosis before structural failure 总被引:2,自引:0,他引:2
Concurrent measurements of combined cortical thickness (CCT) at the midshaft of the second metacarpal and at the proximal juxtametaphyseal radial cortex were made in 234 healthy women aged 46-80 years (group 1) and in 52 women with symptomatic osteoporosis (at least two spontaneous vertebral compressions) (group 2). When -2 standard deviations (SDs) of the mean values in young healthy women (aged 21-45 years) were used as the lower limit of normal measurements, 47% of the subjects in group 1 showed abnormalities: in 25% both bones were abnormal, in 12% the radius alone was abnormal, and in 10% the second metacarpal alone was abnormal. Because 98% of the subjects in group 2 had abnormal CCT measurements, the -2-SD limit of the younger healthy subjects appears to constitute a satisfactory "fracture threshold." Although further research and correlation are required, these simple and inexpensive measurements may be appropriate for mass screening to separate those at greater risk for development of spontaneous vertebral compressions from those at lesser risk. 相似文献
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A Chalmers W J Reynolds D G Oreopoulos H E Meema H Meindok G A deVeber 《Canadian Medical Association journal》1980,123(7):635-638
Among 61 patients undergoing maintenance peritoneal dialysis for an average of 20 months, 13 (21%) had a history of attacks of acute arthritis and 19 (31%) were found to have tender and often swollen joints. Deposits of calcium pyrophosphate dihydrate crystals in articular cartilage were identified in four patients and inflammation probably induced by hydroxyapatite crystals was noted in one. Periarticular calcification was observed in 12 patients and subperiosteal resorption of the phalanges in 20. The average calcium X phosphorus product was significantly higher (P < 0.025) in patients with a history of attacks of acute arthritis or with inflamed joints (58 +/- 12) than in those without (50 +/- 12). In the 19 patients whose treatment was changed to continuous ambulatory peritoneal dialysis there was a significant decrease (P < 0.025) in the calcium X phosphorus product but not in the proportion of patients with attacks of acute arthritis or with inflamed joints. The results indicate that articular complications are frequent among patients undergoing maintenance peritoneal dialysis and may be more common than with long-term hemodialysis. 相似文献
24.
Toivo Jürimäe Krislin Meema Kalle Karelson Priit Purge Jaak Jürimäe 《Clinical physiology and functional imaging》2009,29(5):330-334
The purpose of this cross‐sectional study was to determine the physiological reaction to the different intensity Nordic Walking exercise in young females with different aerobic capacity values. Twenty‐eight 19–24‐year‐old female university students participated in the study. Their peak O2 consumption (VO2 peak kg?1) and individual ventilatory threshold (IVT) were measured using a continuous incremental protocol until volitional exhaustion on treadmill. The subjects were analysed as a whole group (n = 28) and were also divided into three groups based on the measured VO2 peak kg?1 (Difference between groups is 1 SD) as follows: 1. >46 ml min?1 kg?1 (n = 8), 2. 41–46 ml min?1 kg?1 (n = 12) and 3. <41 ml min?1 kg?1 (n = 8). The second test consisted of four times 1 km Nordic Walking with increasing speed on the 200 m indoor track, performed as a continuous study (Step 1 – slow walking, Step 2 – usual speed walking, Step 3 – faster speed walking and Step 4 – maximal speed walking). During the walking test expired gas was sampled breath‐by‐breath and heart rate (HR) was recorded continuously. Ratings of perceived exertion (RPE) were asked using the Borg RPE scale separately for every 1 km of the walking test. No significant differences emerged between groups in HR of IVT (172·4 ± 10·3–176·4 ± 4·9 beats min?1) or maximal HR (190·1 ± 7·3–191·6 ± 7·8 beats min?1) during the treadmill test. During maximal speed walking the speed (7·4 ± 0·4–7·5 ± 0·6 km h?1) and O2 consumption (30·4 ± 3·9–34·0 ± 4·5 ml min?1 kg?1) were relatively similar between groups (P > 0·05). However, during maximal speed walking, the O2 consumption in the second and third groups was similar with the IVT (94·9 ± 17·5% and 99·4 ± 15·5%, respectively) but in the first group it was only 75·5 ± 8·0% from IVT. Mean HR during the maximal speed walking was in the first group 151·6 ± 12·5 beats min?1, in the second (169·7 ± 10·3 beats min?1) and the third (173·1 ± 15·8 beats min?1) groups it was comparable with the calculated IVT level. The Borg RPE was very low in every group (11·9 ± 2·0–14·4 ± 2·3) and the relationship with VO2and HR was not significant during maximal speed Nordic Walking. In summary, the present study indicated that walking is an acceptable exercise for young females independent of their initial VO2 peak level. However, females with low initial VO2 peak can be recommended to exercise with the subjective ‘faster speed walking’. In contrast, females with high initial VO2 peak should exercise with maximal speed. 相似文献
25.
H Meindok A Rapoport D G Oreopoulos S Rabinovich H E Meema S Meema 《Nuclear medicine communications》1985,6(3):141-148
A simple method of quantifying skeletal uptake of 99Tcm-methylene diphosphonate, using a rectilinear scanner and a simultaneously image standard, is described. The pattern of quantified uptake in ten regions of the skeleton, the sacro-iliac joints and kidneys in 57 controls and 54 patients with various metabolic bone disease is presented. This method distinguishes patients with primary hyperparathyroidism and osteomalacia from controls with a sensitivity adequate for clinical purposes. In primary hyperparathyroidism the increased skull uptake of tracer correlated well with levels of serum alkaline phosphatase, plasma parathyroid hormone, urinary hydroxyproline excretion and the degree of intracortical resorption in the metacarpal bones. The skull uptake in oestoporosis was normal or moderately elevated and correlated well with bone mass density measurements of the radius. Patients with osteomalacia also showed the greatest increase in tracer uptake in the skull. Patients with thyrotoxicosis differed from most other patients by showing moderately increased uptake in shafts of long bones. We propose our method of quantitative bone uptake as a useful noninvasive test to detect metabolic bone disease and to monitor responses to therapy of bone disease. 相似文献
26.
H. E. Meema M.D. 《Skeletal radiology》1977,2(1):11-19
This is an outline of radiologic assessment of cortical bone resorption for improved diagnosis of metabolic bone diseases by simple radiographic means: microradioscopy and morphometry. The methodology permits separate assessment of endosteal, intracortical, and periosteal resorption and an evaluation of both the quantity and the quality of cortical bone. 相似文献
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29.
J.E. Harrison K.G. McNeill H.E. Meema D. Oreopoulos S. Rabinovich S. Fenton D.R. Wilson 《Metabolism: clinical and experimental》1977,26(3):255-265
The bone calcium status of 39 patients with chronic renal failure on hemodialysis has been measured by in vivo neutron activation analysis (IVNAA) and reported in terms of a calcium bone index (CaBI) which relates the calcium in a patient to that in a normal person of the same height. In 20 of the 39 cases sequential measurements were made over periods of up to 40 mo. The results are compared with data obtained by radiology and by histological examination of bone biopsies. CaBI values varied from below normal to, in one case, above the range of normal. Many of the higher values were associated with demonstrable osteosclerosis. As found in previous work here with IVNAA, significantly low values of CaBI were associated with vertebral deformities; however, some patients with deformity had normal CaBI values, indicating that these had both local mineral loss (resulting in fracture) and osteosclerosis. Taken all together, the data suggest that more than half the patients have osteosclerosis. Sequential data showed no uniform response to treatment. 相似文献
30.