The ethics of psychopharmacological research in legal minors

Research in psychopharmacology for children and adolescents is fraught with ethical problems and tensions. This has practical consequences as it leads to a paucity of the research that is essential to support the treatment of this vulnerable group. In this article, we will discuss some of the ethical issues which are relevant to such research, and explore their implications for both research and standard care. We suggest that finding a way forward requires a willingness to acknowledge and discuss the inherent conflicts between the ethical principles involved. Furthermore, in order to facilitate more, ethically sound psychopharmacology research in children and adolescents, we suggest more ethical analysis, empirical ethics research and ethics input built into psychopharmacological research design.     

Allgemeine Aspekte der chirurgischen Therapie des nichtkleinzelligen Bronchialkarzinoms

Lung cancer is one of the most common cancers in industrialized nations, dominating in men but also increasing continuously in women. Complete surgical resection of the tumor remains the only curative therapy. A surgical approach requires precise preoperative diagnostic evaluation and staging of the carcinoma as well as the interdisciplinary discussion to determine the individual therapeutic treatment. Surgical therapy of lung cancer is stage dependent and often part of a multimodal approach including adjuvant or neoadjuvant radio- and/or chemotherapy. Close communication with associated specialties is mandatory. Surgical considerations for therapeutic strategies in different lung cancer stages are presented and indications for tumor resections are described. Furthermore, invasive staging techniques are discussed and preoperative evaluation of pulmonary function and its implications on extent of surgical resection are explained.     

Der Folien-Vakuumverband zur Behandlung infizierter Hautdefekte

Zusammenfassung Mit Hilfe einer aufgeklebten Plastikfolie und einer Redon-Saugdrainage kann das sich im Bereich osteomyelitischer Hautdefekte ansammelnde Sekret dauernd abgesaugt werden. Dadurch wird die Ausbildung von Granulationen begünstigt, welche schlie?lich eine plastische Deckung des Defekts mit Spalthaut erlauben.

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Summary Putrid secretion accumulating in osteomyelitic skin defects may be continously evacuated by suction drainage at which the defect is covered by a plastic foil. With time granulation takes place. At last skin grafting with Thiersch or Reverdin flaps will be successful.