全文获取类型
收费全文 | 38472篇 |
免费 | 2635篇 |
国内免费 | 136篇 |
专业分类
耳鼻咽喉 | 529篇 |
儿科学 | 933篇 |
妇产科学 | 600篇 |
基础医学 | 4675篇 |
口腔科学 | 517篇 |
临床医学 | 4094篇 |
内科学 | 7906篇 |
皮肤病学 | 503篇 |
神经病学 | 3396篇 |
特种医学 | 1466篇 |
外科学 | 6537篇 |
综合类 | 501篇 |
一般理论 | 43篇 |
预防医学 | 3310篇 |
眼科学 | 622篇 |
药学 | 2897篇 |
中国医学 | 94篇 |
肿瘤学 | 2620篇 |
出版年
2023年 | 260篇 |
2022年 | 438篇 |
2021年 | 1166篇 |
2020年 | 714篇 |
2019年 | 1070篇 |
2018年 | 1291篇 |
2017年 | 900篇 |
2016年 | 915篇 |
2015年 | 1092篇 |
2014年 | 1648篇 |
2013年 | 2122篇 |
2012年 | 3079篇 |
2011年 | 3120篇 |
2010年 | 1642篇 |
2009年 | 1524篇 |
2008年 | 2616篇 |
2007年 | 2568篇 |
2006年 | 2409篇 |
2005年 | 2409篇 |
2004年 | 2274篇 |
2003年 | 2037篇 |
2002年 | 1889篇 |
2001年 | 365篇 |
2000年 | 301篇 |
1999年 | 368篇 |
1998年 | 352篇 |
1997年 | 281篇 |
1996年 | 255篇 |
1995年 | 197篇 |
1994年 | 196篇 |
1993年 | 154篇 |
1992年 | 165篇 |
1991年 | 192篇 |
1990年 | 137篇 |
1989年 | 106篇 |
1988年 | 100篇 |
1987年 | 82篇 |
1986年 | 67篇 |
1985年 | 78篇 |
1984年 | 77篇 |
1983年 | 73篇 |
1982年 | 87篇 |
1981年 | 59篇 |
1980年 | 49篇 |
1979年 | 38篇 |
1978年 | 38篇 |
1977年 | 27篇 |
1976年 | 23篇 |
1975年 | 28篇 |
1973年 | 24篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
52.
53.
A serotonin (5-HT)-mediated phosphoinositide hydrolysis response was characterized in fibroblasts cultured from rabbit choroid plexus. 5-HT elicited a maximum 8-fold increase in [3H]inositol-phosphate ([3H]IP) formation, while the partial agonists, (+)-lysergic acid diethylamide and (−)-1-(4-bromo-2,5-dimethyoxyphenyl)-2-aminopropane caused 2- and 5-fold increases, respectively. Mianserin, ketanserin, and spiperone were equipotent at blocking the 5-HT-mediated response. Thus, agonist and antagonist profiles indicate interactions with 5-HT2 receptors. 相似文献
54.
Following an encephalopathic illness, a 13-year-old Chinese boy had a partial form of Klüver-Bucy syndrome with emotional disturbance, recent memory loss, hypersexuality, and polyphagia. Other unusual features included narcolepsy, polydipsia, and polyuria. Virologic studies failed to incriminate the etiologic agent, including herpes simplex virus. Brain biopsy of the frontal lobe demonstrated Alzheimer type II astrocytosis. 相似文献
55.
Kevin Gruffydd-Jones Sandra Hollinghurst Sabbi Ward Gordon Taylor 《The British journal of general practice》2005,55(521):918-923
BACKGROUND: There is a high non-attendance rate for traditional clinic-based routine asthma care in general practice. Alternative methods of providing routine asthma care need to be examined. AIM: To examine the cost and effectiveness of targeted routine asthma care in general practice using telephone triage, compared to usual clinic care. DESIGN OF STUDY: An open randomised controlled trial. SETTING: A single semi-rural practice in the southwest of England. METHOD: Adult patients with asthma were randomised to receive either their routine asthma care in the surgery or care by telephone triage. Asthma control parameters, health status and NHS resource utilisation were measured over the 12-month study period. RESULTS: One hundred and ninety-four patients were randomised and 35% per cent more patients (n = 84 versus n = 62) received more than one consultation in the telephone group. Asthma control as measured by the asthma control questionnaire (ACQ) was similar in the clinic and telephone groups: mean change in ACQ = -0.11 (95% CI = -0.32 to 0.11) versus -0.18 (95% CI = -0.38 to 0.02). Mean NHS costs were 210 pounds sterling per patient per year in the telephone group compared to 334 pounds sterling in the clinic group (P-value of bootstrapped difference = 0.071). CONCLUSION: Targeted routine asthma care by telephone triage of adult asthmatics can lead to more asthma patients being reviewed, at less cost per patient and without loss of asthma control compared to usual routine care in the surgery. 相似文献
56.
57.
The craft of surgery has always relied on the use of instruments. Innovations in surgery have paralleled innovations in instrumentation.
Advances in surgical instrumentation continue today and have enabled huge strides in surgical procedures and outcomes during
this generation. Computers and related technology are now changing the interface between the surgeon and the patient, and
are poised to improve patient outcomes by enhancing the surgeon’s skills and training. The application of computer enhanced
telemanipulators, or “robots”, may specifically enhance operations, for example Heller myotomy, that require good visualization
and precise careful dissection of delicate structures. This review covers the pathophysiology of achalasia and its history
of medical and surgical treatment, leading to modern robotic telesurgical approaches. Improvements in outcome from medical
to standard surgical to robotic telesurgical approaches are discussed. Current operative technique for robotic telesurgical
treatment of achalasia is described and the authors conclude with a glimpse of where, in the future, current research endeavors
will lead us in the treatment of achalasia. 相似文献
58.
59.
E D Endean S K Mukhopadhyay L K Fung J L Cronenwett J C Stanley S M Lindenauer 《The Journal of surgical research》1986,40(1):49-54
Basal isolated canine paw blood flow was equally distributed between arteriovenous anastomosis (AVA) and capillary circulations. Norepinephrine decreased AVA flow by 92% and capillary flow by 41%. Dopamine significantly reduced AVA flow by 94% compared to baseline with a 37% reduction in capillary flow. However, with alpha-adrenergic blockade dopamine decreased AVA flow 66% while capillary flow increased 42%. Isoproterenol increased capillary flow almost twofold and appeared to decrease AVA flow, although the latter was statistically insignificant. Differential effects of adrenergic and dopaminergic agonists on canine paw AVA and capillary blood flow suggest the existence of independent regulation of these components of the microcirculation. 相似文献
60.