全文获取类型
收费全文 | 2815篇 |
免费 | 148篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 70篇 |
妇产科学 | 50篇 |
基础医学 | 424篇 |
口腔科学 | 58篇 |
临床医学 | 197篇 |
内科学 | 770篇 |
皮肤病学 | 17篇 |
神经病学 | 141篇 |
特种医学 | 271篇 |
外科学 | 429篇 |
综合类 | 5篇 |
预防医学 | 69篇 |
眼科学 | 45篇 |
药学 | 133篇 |
中国医学 | 6篇 |
肿瘤学 | 269篇 |
出版年
2024年 | 5篇 |
2023年 | 36篇 |
2022年 | 62篇 |
2021年 | 87篇 |
2020年 | 44篇 |
2019年 | 78篇 |
2018年 | 120篇 |
2017年 | 69篇 |
2016年 | 65篇 |
2015年 | 73篇 |
2014年 | 102篇 |
2013年 | 128篇 |
2012年 | 190篇 |
2011年 | 188篇 |
2010年 | 98篇 |
2009年 | 91篇 |
2008年 | 164篇 |
2007年 | 183篇 |
2006年 | 197篇 |
2005年 | 175篇 |
2004年 | 174篇 |
2003年 | 154篇 |
2002年 | 133篇 |
2001年 | 36篇 |
2000年 | 38篇 |
1999年 | 35篇 |
1998年 | 37篇 |
1997年 | 33篇 |
1996年 | 30篇 |
1995年 | 26篇 |
1994年 | 15篇 |
1993年 | 17篇 |
1992年 | 15篇 |
1991年 | 11篇 |
1990年 | 5篇 |
1989年 | 9篇 |
1988年 | 6篇 |
1987年 | 7篇 |
1986年 | 3篇 |
1985年 | 2篇 |
1984年 | 6篇 |
1983年 | 4篇 |
1982年 | 5篇 |
1981年 | 4篇 |
1979年 | 3篇 |
1978年 | 6篇 |
1977年 | 2篇 |
1972年 | 2篇 |
1956年 | 2篇 |
1923年 | 1篇 |
排序方式: 共有2979条查询结果,搜索用时 15 毫秒
51.
Suzuki K Osada N Akasi YJ Suzuki N Sakakibara M Miyake F Maki F Takahashi Y 《Internal medicine (Tokyo, Japan)》2004,43(4):300-305
A 64-year-old man was admitted due to hypokalemia-related myopathy. He was heavy drinker. He felt the stress of alcohol withdrawal during his hospitalization. The patient suffered a cardiopulmonary arrest lasting approximately 5 minutes on the fifth hospital day. One day later, ST-segment elevation was observed in leads I, aV(L), and V(2-6). Emergent cardiac catheterization was performed for suspicion of acute myocardial infarction. Normal coronary arteries with anterior akinesis of the left ventricle were revealed during the procedure. The present case may be an atypical form of "Takotsubo cardiomyopathy" in which the left ventricular contraction is due to focal anterior wall motion abnormalities. 相似文献
52.
Incidence of thrombotic stent occlusion during the first three months after sirolimus-eluting stent implantation in 500 consecutive patients 总被引:6,自引:0,他引:6
Regar E Lemos PA Saia F Degertekin M Tanabe K Lee CH Arampatzis CA Hoye A Sianos G de Feyter P van der Giessen WJ Smits PC van Domburg RT Serruys PW 《The American journal of cardiology》2004,93(10):1271-1275
Sirolimus-eluting stents have been used in our institution for all percutaneous interventions, without clinical or anatomic exclusion criteria, as part of the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital registry. We analyzed the incidence of (sub)acute stent thrombosis after sirolimus-eluting stent implantation in an unselected population of 510 consecutive patients. At 3-month follow-up, (sub)acute stent thrombosis was diagnosed in 2 patients (0.4%) 6 hours and 11 days after the procedure, respectively. These cases occurred in diabetic women with complex coronary lesions. Intravascular ultrasound examination showed inadequate stent expansion and uncovered distal dissection as possible mechanical explanations for the thrombosis. 相似文献
53.
Masashi Yoshida Ichiro Inoue Takuji Kawagoe Masaharu Ishihara Yuji Shimatani Satoshi Kurisu Kengo Fukushima Kusano Tohru Ohe 《Catheterization and cardiovascular interventions》2006,68(1):112-117
BACKGROUND: Although thrombolysis is a standard therapy in cases of pulmonary embolism (PE), fatal outcome is often observed. We designed and investigated the efficacy of a novel percutaneous catheter therapy, rotational bidirectional thrombectomy (ROBOT), for PE. METHODS AND RESULTS: Eighteen patients with acute massive PE (Miller score > or = 20) were included in this study. We separated them into two groups [group A (n = 10), thrombolysis; group B (n = 8): thrombolysis and ROBOT or ROBOT alone]. There was no difference in the hemodynamic indices between the groups at diagnosis. ROBOT was designed to fragment emboli by rotating a regular pigtail catheter. Three deaths occurred in group A because of hemodynamic impairment, but there was no death in group B. One day after treatment, systolic pulmonary artery pressure had decreased from 53 +/- 8 to 30 +/- 8 mm Hg (P < 0.05) in group B and from 54 +/- 5 to 42 +/- 19 mm Hg (NS) in group A. The hospitalization period in group B was shorter than that in group A (17 +/- 6 vs. 27 +/- 10 days, P < 0.05). CONCLUSION: ROBOT therapy results in a significant, rapid improvement in the hemodynamic situation and in a better outcome than conventional therapy in patients with acute massive pulmonary embolism. 相似文献
54.
55.
56.
Dai Keino Yoshimitsu Tsuzuki Takashi Mori Shiori Kakuage Marie Nakano Kentaro Asoh Tetsuya Mori Akitoshi Kinoshita Hitoshi Yamamoto 《Pediatrics international》2015,57(5):1017-1020
There have been few reports regarding infective endocarditis (IE) in patients with leukemia. In the first case, a 15‐year‐old girl with Down syndrome was diagnosed with acute lymphoblastic leukemia. On admission, methicillin‐sensitive Staphylococcus aureus (MSSA) was detected on blood culture. Echocardiography was performed because MSSA was detected repeatedly even after treatment. Vegetation in all of the atria and ventricles met the Duke criteria defining IE. She died of multiple organ failure 21 days after diagnosis. In the second case, an 11‐year‐old boy with acute myeloid leukemia underwent peripheral blood stem cell transplantation (PBSCT). He had fever 68 days after PBSCT, and methicillin‐resistant S. aureus (MRSA) was detected on blood culture. Echocardiography showed vegetation in the right atrium and ventricle. Daptomycin was administered for 7 weeks, and recurrence was not observed. IE should be considered when S. aureus bacteremia is documented even in patients with leukemia. 相似文献
57.
Hajime Uchida Akinari Fukuda Matsunami Masatoshi Kengo Sasaki Takanobu Shigeta Hiroyuki Kanazawa Atsuko Nakazawa Osamu Miyazaki Shunsuke Nosaka Seisuke Sakamoto Mureo Kasahara 《Pediatric transplantation》2015,19(6):E142-E145
The management of LSRS is a crucial problem to ensure a sufficient PV flow during pediatric LT. Although several techniques have been indicated to solve this problem, a more appropriate approach to LSRS is still needed in pediatric LT. We herein present a modified surgical approach to the ligation of LSRS via the left side of the IVC for a nine‐month‐old boy with severe portal hypertension and a history of Kasai portoenterostomy. LSRS was identified and exposed through the left side of the IVC and the dorsal surface of the pancreas from the superior side of the body of the pancreas. The post‐operative course was uneventful with an excellent PV flow. The central approach for the ligation of LSRS is worth considering as an alternative procedure for a patient with collateral vessels and a history of multiple laparotomies. 相似文献
58.
Masatoshi Matsunami Akira Ishiguro Akinari Fukuda Kengo Sasaki Hajime Uchida Takanobu Shigeta Hiroyuki Kanazawa Seisuke Sakamoto Motoki Ohta Hisaya Nakadate Reiko Horikawa Atsuko Nakazawa Mika Ishige Koichi Mizuta Mureo Kasahara 《Pediatric transplantation》2015,19(3):E70-E74
PC is produced in the liver and inhibits blood coagulation by catalyzing active factors V and VIII. PC deficiency causes abnormal blood clotting that is difficult to regulate by anticoagulative treatments. Four reports of PC deficiency treated with LTx have been published; however, no report of DLT as a therapy for PC deficiency is available. We describe a case of a 23‐month‐old girl who received DLT for compound heterozygous PC deficiency. Her PC activity was below 5%. She developed intracranial lesion and frequent refractory purpura fulminans. Both her parents had heterozygous mutations of PC genes and were excluded as living donors. Furthermore, she was a low priority on the waiting list of deceased‐donor transplantation. We performed living DLT using the liver from a patient with MSUD. Activated PC concentrate safely supported the perioperative period. After DLT, she maintained normal PC activities and BCAA levels. This is the first case of PC deficiency successfully treated by living DLT with MSUD. We propose that DLT using liver from patients with MSUD is a treatment option for PC deficiency. 相似文献
59.
Masami Kosuge Kazuo Kimura Toshiyuki Ishikawa Tomoaki Shimizu Takeshi Takamura Kengo Tsukahara Yoshio Tahara Naoki Nozawa Eri Furukawa Osamu Tochikubo Mitsugi Sugiyama Satoshi Umemura 《Circulation journal》2004,68(6):526-531
BACKGROUND: The clinical significance of the white blood cell (WBC) count on admission in relation to the duration of ischemia in acute myocardial infarction (AMI) remains unclear. METHODS AND RESULTS: The relationship of the WBC count on admission to myocardial reperfusion was examined in 135 patients with recanalization of an anterior AMI within 6 h of symptom onset. Patients were classified according to the WBC count on admission: Group L (n=75), WBC count <12,000 cells/mm(3) and group H (n=60), WBC count >or=12,000 cells/mm(3). Peak creatine kinase (CK) was higher and impaired myocardial reperfusion, defined as a myocardial blush grade of 0/1, was more frequent in group H than in group L. Among the patients in group H, those with early (3 h) recanalization; however, peak CK and the incidence of impaired myocardial reperfusion were similar in these subgroups of patients. Multivariate analysis showed that WBC count >or=12,000 cells/mm(3) on admission was an independent predictor of impaired myocardial reperfusion in patients with early recanalization (odds ratio 7.9, p=0.04), but not in those with late recanalization. CONCLUSIONS: A higher WBC count may be associated with progression of myocardial damage after recanalization in patients with early recanalization of an anterior AMI. 相似文献
60.
Laparoscopic total gastrectomy for advanced gastric cancer in a patient with situs inversus totalis 下载免费PDF全文
Kengo Shibata Hideki Kawamura Nobuki Ichikawa Kazuaki Shibuya Tadashi Yoshida Yosuke Ohno Shigenori Homma Akinobu Taketomi 《Asian journal of endoscopic surgery》2018,11(1):39-42
Situs inversus totalis (SIT) is a rare congenital anomaly. Generally, laparoscopic surgery is difficult to perform in patients with SIT because of both the potential challenges associated with unexpected vascular anomalies and the lack of standardized strategy for handling such cases. This is the first report of laparoscopic total gastrectomy with lymph node dissection for advanced gastric cancer in a patient with SIT. A 79‐year‐old man with SIT was diagnosed with advanced gastric cancer. We performed laparoscopic total gastrectomy with modified D2 lymph node dissection (D2 without splenectomy) and esophagojejunal anastomosis using an overlap method involving retrocolic Roux‐en‐Y reconstruction. The total operating time was 232 min, and blood loss was 110 mL. There were no postoperative complications. In summary, laparoscopic total gastrectomy for gastric cancer can be performed safely, even in a patient with SIT. 相似文献