全文获取类型
收费全文 | 20224篇 |
免费 | 1586篇 |
国内免费 | 73篇 |
专业分类
耳鼻咽喉 | 143篇 |
儿科学 | 360篇 |
妇产科学 | 415篇 |
基础医学 | 3105篇 |
口腔科学 | 695篇 |
临床医学 | 2021篇 |
内科学 | 4505篇 |
皮肤病学 | 276篇 |
神经病学 | 1603篇 |
特种医学 | 897篇 |
外国民族医学 | 1篇 |
外科学 | 2983篇 |
综合类 | 197篇 |
一般理论 | 7篇 |
预防医学 | 1333篇 |
眼科学 | 355篇 |
药学 | 1118篇 |
中国医学 | 17篇 |
肿瘤学 | 1852篇 |
出版年
2022年 | 167篇 |
2021年 | 354篇 |
2020年 | 194篇 |
2019年 | 265篇 |
2018年 | 363篇 |
2017年 | 288篇 |
2016年 | 356篇 |
2015年 | 352篇 |
2014年 | 456篇 |
2013年 | 628篇 |
2012年 | 991篇 |
2011年 | 1050篇 |
2010年 | 588篇 |
2009年 | 535篇 |
2008年 | 944篇 |
2007年 | 942篇 |
2006年 | 996篇 |
2005年 | 906篇 |
2004年 | 899篇 |
2003年 | 933篇 |
2002年 | 913篇 |
2001年 | 598篇 |
2000年 | 637篇 |
1999年 | 617篇 |
1998年 | 276篇 |
1997年 | 222篇 |
1996年 | 213篇 |
1995年 | 148篇 |
1994年 | 169篇 |
1993年 | 168篇 |
1992年 | 460篇 |
1991年 | 456篇 |
1990年 | 425篇 |
1989年 | 394篇 |
1988年 | 427篇 |
1987年 | 356篇 |
1986年 | 374篇 |
1985年 | 333篇 |
1984年 | 245篇 |
1983年 | 195篇 |
1982年 | 110篇 |
1981年 | 111篇 |
1979年 | 200篇 |
1978年 | 125篇 |
1977年 | 119篇 |
1976年 | 116篇 |
1975年 | 112篇 |
1974年 | 117篇 |
1973年 | 123篇 |
1971年 | 104篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
32.
Psychiatric morbidity in Hobart's dependent aged 总被引:1,自引:0,他引:1
D W Kay T A Holding B Jones S Littler 《The Australian and New Zealand journal of psychiatry》1987,21(4):463-475
Psychiatric morbidity in the dependent aged was studied in the elderly population of Hobart's nursing homes and long-stay hospitals. Only patients with home addresses in Hobart and who were admitted for the first time aged 70 years or over were included. Three hundred and twelve persons were interviewed with a standard interview, and an informant was interviewed when appropriate. The medical records were searched for diagnoses and drug treatments. Physical disability was rated on an ad hoc scale. Comparisons were made of the prevalence of dementia, depression and anxiety in different types of unit, and between these and two domiciliary samples, one of which received domiciliary nursing services (n = 100) and the other not (n = 100). The differential use of institutions by men and women, and a possible sex difference in the prevalence of dementia is discussed. 相似文献
33.
Localized primary (AL) amyloid tumor of the breast. Cytologic, histologic, immunocytochemical and ultrastructural observations 总被引:2,自引:0,他引:2
J F Silverman D J Dabbs H T Norris W J Pories J Legier S Kay 《The American journal of surgical pathology》1986,10(8):539-545
Two examples of localized primary amyloid tumor of the breast are presented, including one patient with metachronous bilateral lesions. Our findings and review of the literature indicate that this rare lesion occurs predominantly in elderly females and can be mammographically and clinically confused with carcinoma. Fine-needle aspiration biopsy can be a useful procedure to make a preliminary diagnosis. Congo red staining with prior potassium permanganate incubation confirmed the AL type of amyloid in our two cases; this might be the predominant type in the localized form involving the breast. Immunofluorescence studies demonstrated IgA, with kappa and lambda light-chain deposition within the amyloid foci in one case, and intracytoplasmic IgG with both light chains within plasma cells and amyloid deposits of the second case. Ultrastructural examination of one of the cases showed characteristic findings of straight, nonbranching fibrils of 4-9 nm, diagnostic of amyloid. From our findings and a review of the literature, we conclude that amyloid tumors of the breast can occur in three separate settings: secondary amyloidosis, systemic or multiple myeloma associated amyloidosis, and as a localized primary type having a benign course. 相似文献
34.
35.
Hiroki Hamanaka Nobuaki Maeda Masaharu Noda 《The European journal of neuroscience》1997,9(11):2297-2308
Protein tyrosine phosphatase ζ (PTPζRPTPβ) is a proteoglycan-type receptor-like protein tyrosine phosphatase specifically expressed in the brain. In addition to the transmembrane form (PTPζ-A), the extracellular splice variant (PTPζ-S) occurs as a major soluble chondroitin sulphate proteoglycan in the brain. We prepared antibodies which specifically recognize PTPζ-A and -S, and analysed the carbohydrate structures on the two PTPζ isoforms in the developing chick brain. lmmunoprecipitation experiments using these antibodies revealed that almost all of the keratan sulphate recognized by a monoclonal antibody (5D4) was exclusively bound to PTPζ-A and PTPζ-S. Addition of keratan sulphate to these proteoglycans markedly increased from embryonic day (E) 11, in contrast to the addition of LeX and HNK-1 carbohydrates, which gradually increased during development in accordance with expression of the core proteins, suggesting that keratan sulphate modification plays some specific roles. Moreover, at the early embryonic stage keratan sulphate was observed only in several restricted regions, especially at boundary regions such as the roof plate of the tectum, the zona limitans intrathalamica in the diencephalon, and the mesencephalon-metencephalon boundary. At the mesencephalon-metencephalon boundary, keratan sulphate modification of PTPζ isoforms was specifically observed from E3 to E6 on a ring of cells encircling the neural tube and their radially oriented processes, which were identified as radial glial fibres. This expression pattern of keratan sulphate spatiotemporally corresponded well to the formation of the fovea isthmi, a groove separating the mesencephalon from the metencephalon. These results suggest that carbohydrates including keratan sulphate on PTPζ isoforms play important roles in brain development by modulating the cell-cell and/or cell-substrate interactions mediated by these molecules. 相似文献
36.
Leah L. Albers Deborah Anderson Leslie Cragin Susan Moore Daniels Christine Hunter Kay D. Sedler Dusty Teaf 《Journal of Midwifery & Women's Health》1996,41(4):269-276
We conducted an observational cohort study in three nurse-midwifery services to identify patient characteristics and clinical care measures related to perineal trauma at birth. Data were collected on all women who began care with a nurse-midwife in labor, using an adaptation of the Nurse-Midwifery Clinical Data Set (n = 3,049). Study variables included demographics, perineal management techniques and position for birth, and other intrapartum care and events. Univariate and multivariate analyses showed that episiotomy was strongly related to fetal bradycardia, prolonged second stage, ethnic status, and maternal education level. Warm compresses and flexion/counterpressure to slow delivery were protective. Spontaneous lacerations were influenced by these factors as well. The lateral position for birth was protective, and use of oils or lubricants and the lithotomy position increased lacerations. Multisite studies in nurse-midwifery practices may provide an ideal means of determining effective care measures in healthy populations. 相似文献
37.
38.
Ductal adenoma of the breast 总被引:1,自引:0,他引:1
Ductal adenoma is a recently described benign tumour of the breast that can be mistaken for carcinoma in both frozen and paraffin sections. Such a case is presented. Fortunately a mastectomy was not performed, but the patient did undergo axillary node dissection. Surgeons and pathologists should familiarize themselves with this lesion so that patients do not have to undergo unnecessary mastectomies and axillary node dissections. 相似文献
39.
C. R. Goucke MB ChB FFARACS J. P. Keaveny MB BCh BAO FFARCS B Kay DMSc MB ChB FFARCS T. E. J. Healy MSc MD FFARCS M. Ryan MB ChB FFARCS 《Anaesthesia》1990,45(4):329-331
Eighty-two outpatients who received general anaesthesia for surgical removal of maxillary or mandibular third molars were given either diclofenac 75 mg or nefopam 20 mg intramuscularly for postoperative pain control. They and the control group were also allowed oral paracetamol as required. The results showed that there was no significant pain relief from these single intramuscular injections. 相似文献
40.
K Kuboki M Sakai I Kuwajima S Maeda S Ohkawa K Ueda K Kuramoto 《Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics》1992,29(5):390-395
In order to investigate whether intravenous bolus injection of isosorbide dinitrate (ISDN) is a safe and efficient therapy in aged patients with congestive heart failure, we studied acute hemodynamic effects in 11 patients. Peak effects on preload were observed after 5 to 10 minutes of bolus injection and unloading effects continued effectively for 60 minutes. At peak effect, pulmonary systolic pressure decreased from 50.2 +/- 2.6 to 36.2 +/- 2.6 mmHg (-28.5%, p less than 0.01) and pulmonary end diastolic pressure decreased from 25.0 +/- 2.2 to 18.5 +/- 2.1 mmHg (-26.0%, p less than 0.01). Mean pulmonary artery wedge pressure decreased from 23.4 +/- 2.2 to 16.0 +/- 2.1 mmHg (-31.6%, p less than 0.01). Mean right atrial pressure decreased from 10.5 +/- 1.8 to 7.4 +/- 2.0 mmHg (-29.5%, p less than 0.01). Blood pressure, heart rate, cardiac index, systemic and pulmonary vascular resistance showed no significant changes. Thus, intravenous bolus injection of ISDN showed a potent vasodilator effects on preload, and may be a safe and useful treatment for aged patients with acute congestive heart failure. 相似文献