全文获取类型
收费全文 | 6746篇 |
免费 | 632篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 81篇 |
儿科学 | 252篇 |
妇产科学 | 214篇 |
基础医学 | 808篇 |
口腔科学 | 77篇 |
临床医学 | 1037篇 |
内科学 | 1272篇 |
皮肤病学 | 87篇 |
神经病学 | 742篇 |
特种医学 | 98篇 |
外科学 | 573篇 |
综合类 | 91篇 |
一般理论 | 8篇 |
预防医学 | 1094篇 |
眼科学 | 131篇 |
药学 | 451篇 |
中国医学 | 6篇 |
肿瘤学 | 368篇 |
出版年
2023年 | 96篇 |
2022年 | 135篇 |
2021年 | 259篇 |
2020年 | 194篇 |
2019年 | 280篇 |
2018年 | 281篇 |
2017年 | 239篇 |
2016年 | 208篇 |
2015年 | 221篇 |
2014年 | 312篇 |
2013年 | 351篇 |
2012年 | 541篇 |
2011年 | 549篇 |
2010年 | 259篇 |
2009年 | 187篇 |
2008年 | 375篇 |
2007年 | 350篇 |
2006年 | 319篇 |
2005年 | 265篇 |
2004年 | 248篇 |
2003年 | 207篇 |
2002年 | 178篇 |
2001年 | 101篇 |
2000年 | 73篇 |
1999年 | 68篇 |
1998年 | 32篇 |
1997年 | 30篇 |
1996年 | 25篇 |
1995年 | 26篇 |
1994年 | 19篇 |
1993年 | 27篇 |
1992年 | 63篇 |
1991年 | 71篇 |
1990年 | 67篇 |
1989年 | 55篇 |
1988年 | 30篇 |
1987年 | 44篇 |
1986年 | 55篇 |
1985年 | 47篇 |
1984年 | 23篇 |
1983年 | 30篇 |
1981年 | 34篇 |
1979年 | 52篇 |
1977年 | 25篇 |
1976年 | 20篇 |
1975年 | 25篇 |
1974年 | 33篇 |
1973年 | 34篇 |
1972年 | 40篇 |
1971年 | 24篇 |
排序方式: 共有7390条查询结果,搜索用时 0 毫秒
71.
Saman K. Hashmi Katie Bergstrom Alison A. Bertuch Jenny M. Despotovic Eyal Muscal Fan Xia Weimin Bi Andrea Marcogliese Rosa Diaz 《Pediatric blood & cancer》2019,66(1)
Neutropenia in pediatric patients can be due to a variety of disorders. We describe two patients who underwent extensive evaluation over many years for arthralgias and moderate neutropenia of unclear etiology. Genetic testing identified a pathogenic variant in PSTPIP1 (proline‐serine‐threonine phosphatase‐interacting protein 1) in both patients. Markedly elevated inflammatory markers and zinc levels confirmed the rare diagnosis of PSTPIP1‐associated myeloid‐related proteinemia inflammatory (PAMI) syndrome, tailoring treatment. Neutropenia is common in patients with PAMI syndrome. Unique mutations seen in PAMI syndrome may account for the specific phenotypic features of this disorder. 相似文献
72.
Amber J. Hromi‐Fiedler Gabriela dos Santos Buccini Muriel Bauermann Gubert Katie Doucet Rafael Prez‐Escamilla 《Maternal & child nutrition》2019,15(1)
Scaling up breastfeeding programmes has not been highly prioritized despite overwhelming evidence that breastfeeding benefits the health of mothers and children. Lack of evidence‐based tools for scaling up may deter countries from prioritizing breastfeeding. To fill this gap, Becoming Breastfeeding Friendly (BBF) was developed to guide countries in effectively scaling up programmes to protect, promote, and support breastfeeding. BBF includes an evidence‐based toolbox that consists of a BBF Index, case studies, and a 5‐meeting process. These three interrelated components enable countries to assess their breastfeeding scaling up environment, identify gaps, propose policy recommendations, develop a scaling up plan, and track progress. The toolbox was developed based on current evidence and expert guidance from a Technical Advisory Group, which was composed of global breastfeeding and metric experts with experience in the scaling up of health and nutrition programmes in low‐, middle‐, and high‐income countries. The BBF toolbox required a step‐by‐step iterative approach to describe and systematize each component, thus an operational manual was developed. The BBF toolbox and BBF operational manual underwent intensive pretesting in two countries, Ghana and Mexico, resulting in the modification of each component plus the operational manual. Pretesting continues in six additional countries demonstrating that BBF is a robust and dynamic multi‐sectoral process that, with relatively minor adaptations, can be successfully implemented in countries across world regions. 相似文献
73.
Joe E.Acker Ⅲ Todd J.Crocco Marc K.Eckstein Edward C.Jauch Neil M.Meltzer John W.Munn Charles Sand Jeffrey L.Saver Brian Eigel Brian R.Gilpin Mark Schoeberl Penelope Solis Katie B.Hortort 曹勇军 李瑞霞 刘芳 刘春风 《国际脑血管病杂志》2008,16(7):481-498
尽管卒中的预防、诊断、治疗和康复已取得一些进展,但卒中在美国仍然是第三大死亡原因和长期残疾的主要原因.每年约有70万人新发或复发卒中[1].在过去10年里,急性卒中诊治的一些进展,包括纤溶和其他短期疗法的引入,突出显示了急诊医疗服务(emergency medical services,EMS)机构和急诊医疗服务体系(emergency medical services systems,EMSS)在优化卒中医疗中的关键作用[2-7]. 相似文献
74.
Effects of in utero exposure to finasteride on androgen-dependent reproductive development in the male rat. 总被引:3,自引:0,他引:3
Christopher J Bowman Norman J Barlow Katie J Turner Duncan G Wallace Paul M D Foster 《Toxicological sciences》2003,74(2):393-406
Finasteride is a specific inhibitor of type II 5alpha-reductase, the enzyme that converts testosterone (T) to the more potent androgen receptor agonist dihydrotestosterone (DHT). In utero exposure to androgen receptor antagonists and T biosynthesis inhibitors have induced permanent effects on androgen-sensitive end points such as anogenital distance (AGD), nipple retention, and malformations of the male rat reproductive tract. The objectives of this study were to (1) characterize the dose response of finasteride-mediated alterations in androgen-dependent developmental end points, (2) determine whether prenatal exposure to finasteride permanently decreases AGD or results in nipple retention, and (3) evaluate whether AGD or nipple retention is predictive of adverse alterations in the male reproductive tract. Pregnant Crl:CD(SD)BR rats (n=5-6/group) were gavaged with either vehicle or finasteride at 0.01, 0.1, 1.0, 10, or 100 mg/kg/day on gestation days 12 to 21. All male offspring were monitored individually until necropsy on postnatal day (PND) 90. The present study design has been used previously for other antiandrogens and is sensitive to perturbations of the male rat reproductive tract. Decreases in AGD on PND 1 and increases in areolae-nipple retention on PND 13 were significantly different from controls in all finasteride-exposed male rats. Finasteride-induced changes in AGD and nipple retention were permanent in male rats exposed to finasteride at and above 0.1 mg/kg/day. On PND 90, dorsolateral and ventral prostate lobes were absent in 21 to 24% of rats exposed to 100 mg/kg/day finasteride and weighed significantly less at and above 10 mg/kg/day. In the highest dose group, 73% of animals had ectopic testes, much higher than previously reported. The most sensitive malformation other than decreased AGD and nipple retention was the dose-dependent increase in hypospadias. The lowest observed adverse effect level (LOAEL) for finasteride-induced permanent effects in this study was 0.1 mg/kg/day based on permanent changes in AGD and nipple retention. Finasteride-induced changes in AGD and retention of nipples were highly predictive of hypospadias, ectopic testes, and prostate malformations even though some animals with retained nipples or decreased AGD may not have had other reproductive tract malformations. In summary, prenatal exposure to finasteride specifically inhibited DHT-mediated development with little to no change in T-mediated development. 相似文献
75.
76.
77.
78.
79.
ABSTRACTHybrid organizations in modern health movements adopt multiple organizational logistics, allowing them to more effectively achieve social change. We conducted an analysis of 152 probreastfeeding organization websites categorized as institutionalized organizations, grassroots organizations, or hybrid organizations. Through a series of ANOVA analyses, we found that hybrid’s websites provide significantly more useful health care information, better maintained dialogue with members, more efficiently mobilized members, commoditized health care issues less, and created member identity while maintaining institutional ties. Ultimately, hybrids tended to incorporate the positive elements from both grassroots and institutional organizations, while rejecting many of the negative elements. 相似文献
80.
Burgio Francesca Benavides-Varela Silvia Toffano Roberta Palmer Katie Meneghello Francesca Arcara Giorgio Semenza Carlo 《Neurological sciences》2022,43(1):299-303
Neurological Sciences - Patients with mild cognitive impairment (MCI) might experience difficulties in numerical and financial abilities of daily living that compromise their autonomy. The aim of... 相似文献